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Volume 42, IECBS 2024
 
 
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Biol. Life Sci. Forum, 2025, IECGE 2024

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Number of Papers: 2
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19 pages, 234 KiB  
Conference Report
Abstracts of the 2nd International Electronic Conference on Genes
by Selvarangan Ponnazhagan
Biol. Life Sci. Forum 2025, 43(1), 1; https://doi.org/10.3390/blsf2025043001 - 28 Mar 2025
Viewed by 244
Abstract
The 2nd International Electronic Conference on Genes (IECGE2024) was organized by the MDPI open access journal Genes and held online from the 11th to 13th December 2024. This conference provided leading scientists with an online platform to share their latest research and engage [...] Read more.
The 2nd International Electronic Conference on Genes (IECGE2024) was organized by the MDPI open access journal Genes and held online from the 11th to 13th December 2024. This conference provided leading scientists with an online platform to share their latest research and engage in exciting discussions. The main topics and sessions of the conference were as follows: Non-coding RNAs in Health and Diseases; Genetic Diagnosis and Targeted Therapy in Cancer; Microbial Genetics and Genomics; Technologies and Resources for Genetics Research; Human Genomics and Genetic Diseases. This was an excellent opportunity for researchers and scientists to interact with each other, communicate with their colleagues, learn from each other, share ideas and results, help solve problems, and suggest alternative options for a better future. Full article
5 pages, 641 KiB  
Proceeding Paper
mRNA-Based Biomarker Identification for Targeted Therapy Development in Pancreatic Cancer
by Saima Firdaus and Rafat Parveen
Biol. Life Sci. Forum 2025, 43(1), 2; https://doi.org/10.3390/blsf2025043002 - 31 Mar 2025
Viewed by 284
Abstract
Pancreatic cancer is one of the highly malignant cancers that have poor prognosis and limited treatment options. The development of targeted therapies is important for improving patient outcomes. In this study, we analyzed the datasets from the GEO database to identify potential mRNA [...] Read more.
Pancreatic cancer is one of the highly malignant cancers that have poor prognosis and limited treatment options. The development of targeted therapies is important for improving patient outcomes. In this study, we analyzed the datasets from the GEO database to identify potential mRNA biomarkers for pancreatic cancer. Differentially expressed gene (DEG) analysis was performed in R to identify genes that expressed differentially between tumor and normal samples. TFF1 and LAMC2 emerged as key candidate genes for pancreatic cancer among the identified DEGs. Additionally drugs approved by the FDA were repurposed as an inhibitor against key genes. These findings suggest that these genes play a significant role in pancreatic cancer progression and have the potential to serve as molecular elements for targeted therapies. Full article
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