Follow-up of Interleukin 6 and Other Blood Markers during the Hospitalization of COVID-19 Patients: A Single-Center Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients and Samples
2.2. Negative and Positive Events
2.3. Blood Measurements
2.4. Detection of Viremia
2.5. Ethics Issues
2.6. Statistical Analysis
3. Results and Discussion
3.1. Levels of Blood Markers in COVID-19 Patients Requiring and Not Requiring Hospitalization
3.2. Time Patterns of IL-6 and Other Blood Markers during COVID-19 Course in Severe–Critical Patients
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Blood Markers Kits | Measuring Range of Test | Reference Values (Healthy Population) | Units |
---|---|---|---|
Maglumi IL-6 | 0.5–5000 | <7.0 | pg/mL |
Maglumi PCT | 0.01–100 | <0.05 | ng/mL |
Maglumi D-dimer | 100–10,000 | <500 | ng FEU/mL |
Elecsys Anti-SARS-CoV-2 S | 0.40–250 | <0.80 | U/mL |
Elecsys Cortisol II | 0.05–63.4 | 5.0–25 * | ug/dL |
Elecsys DHEA-S | 0.1–1000 | 20–44 y: 60.9–340 (F)/88.9–492 (M) ** 45–74 y: 35.4–256 (F)/33.6–331 (M) ** >75 y: 12.0–154 (F)/16.2–123 (M) ** | ug/dL |
Elecsys 25-OH Vitamin D III | 3.0–120 | >20 (sufficient) >30 (optimum) | ng/mL |
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Garrido, M.P.; Vaswani, V.; Contreras, K.; Barberán, M.; Valenzuela-Valderrama, M.; Klajn, D.; Romero, C.; Vial Covarrubias, M.J.; Cornejo, R.A. Follow-up of Interleukin 6 and Other Blood Markers during the Hospitalization of COVID-19 Patients: A Single-Center Study. COVID 2022, 2, 1584-1593. https://doi.org/10.3390/covid2110114
Garrido MP, Vaswani V, Contreras K, Barberán M, Valenzuela-Valderrama M, Klajn D, Romero C, Vial Covarrubias MJ, Cornejo RA. Follow-up of Interleukin 6 and Other Blood Markers during the Hospitalization of COVID-19 Patients: A Single-Center Study. COVID. 2022; 2(11):1584-1593. https://doi.org/10.3390/covid2110114
Chicago/Turabian StyleGarrido, Maritza P., Varsha Vaswani, Katherinne Contreras, Marcela Barberán, Manuel Valenzuela-Valderrama, Diana Klajn, Carmen Romero, María Jesús Vial Covarrubias, and Rodrigo Alfredo Cornejo. 2022. "Follow-up of Interleukin 6 and Other Blood Markers during the Hospitalization of COVID-19 Patients: A Single-Center Study" COVID 2, no. 11: 1584-1593. https://doi.org/10.3390/covid2110114