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BioChem, Volume 2, Issue 1

March 2022 - 8 articles

Cover Story: Polyoxometalates (POMs) such as decavanadate (V10) represent a broad class of anionic inorganic clusters whose features make them attractive materials in a wide range of fields such as catalysis, electrochemistry, biological chemistry (including protein crystallography), environmental applications such as in the decomposition of emergent pollutants as well as biomedicine with a focus on cancer, and bacterial and viral infections. Despite the increasing number of studies in the last decade investigating biomedicine effects on POMs, the underlying mechanisms of action still remain elusive. In the image, it is suggested that decavanadate putative interactions with viral membrane proteins, such as hemagglutinin (green), will prevent the early stage of infection. Additional inhibition of neuraminidase (dark green) would prevent a later stage of infection. View this paper
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Articles (8)

  • Review
  • Open Access
3 Citations
7,354 Views
11 Pages

Translating Biochemistry Concepts into Cartoons and Graphic Narratives: Potential and Pitfalls

  • Mireia Alemany-Pagès,
  • Rui Tavares,
  • Anabela Marisa Azul and
  • João Ramalho-Santos

17 March 2022

Simple biochemical concepts can be hard to grasp by non-specialists, even when they are related to practical contexts in industry, day-to-day activities, or well-acknowledged pathological conditions. This is especially important in instances where ac...

  • Communication
  • Open Access
1 Citations
3,316 Views
11 Pages

UALGORITMO, a New Instrument of the University of Algarve for Scientific Outreach

  • José Bragança,
  • Sónia Figueiredo,
  • Carla Alexandra Rego,
  • Filomena dos Reis Conceição and
  • Saúl Neves de Jesus

3 March 2022

Researchers at Universities generate and convey the knowledge acquired through communications in specialized (inter)national journals and congresses. An effort to share the scientific achievements with the general public is extremely important. For t...

  • Communication
  • Open Access
3,896 Views
10 Pages

An Unconventional Ligand for Scribble PDZ-4 Domain Mediates Its Interaction with Dusp26

  • Raffaella Gallo,
  • Erika De Sensi,
  • Francesca Storino and
  • Simona Panni

15 February 2022

PDZ domains are involved in many cellular processes and are key regulators of the cell physiology. A huge number of studies have investigated the binding specificity of PDZ domains to the carboxyl-terminal sequence of target proteins, while the molec...

  • Article
  • Open Access
4 Citations
6,504 Views
19 Pages

Untargeted Mass Spectrometry Approach to Study SARS-CoV-2 Proteins in Human Plasma and Saliva Proteome

  • Lisa Pagani,
  • Clizia Chinello,
  • Allia Mahajneh,
  • Francesca Clerici,
  • Lucrezia Criscuolo,
  • Andrea Favalli,
  • Paola Gruarin,
  • Renata Grifantini,
  • Alessandra Bandera and
  • Andrea Lombardi
  • + 5 authors

8 February 2022

Since the start of the COVID-19 outbreak, more than four million people have died of this disease. Given its ability to provide a precise response, mass spectrometry-based proteomics could represent a useful tool to study this pathology. To this end,...

  • Review
  • Open Access
12 Citations
6,456 Views
21 Pages

Heme-Based Gas Sensors in Nature and Their Chemical and Biotechnological Applications

  • Ana Claudia Silva Gondim,
  • Wellinson Gadelha Guimarães and
  • Eduardo Henrique Silva Sousa

8 February 2022

Sensing is an essential feature of life, where many systems have been developed. Diatomic molecules such as O2, NO and CO exhibit an important role in life, which requires specialized sensors. Among the sensors discovered, heme-based gas sensors comp...

  • Review
  • Open Access
4 Citations
11,356 Views
16 Pages

Monocytes in Neonatal Bacterial Sepsis: Think Tank or Workhorse?

  • Caitlin Doughty,
  • Louise Oppermann,
  • Niels-Ulrik Hartmann,
  • Stephan Dreschers,
  • Christian Gille and
  • Thorsten Orlikowsky

7 January 2022

Infection and sepsis remain among the leading causes of neonatal mortality. The susceptibility of newborns to infection can be attributed to their immature immune system. Regarding immune response, monocytes represent a numerically minor population o...

  • Concept Paper
  • Open Access
4,654 Views
7 Pages

31 December 2021

Bipolar Disorder (BD), a chronic mental illness, does not have an ideal treatment, and patients with BD have a higher chance of being diagnosed with alcohol abuse, liver disease, and diabetes. The goal of treatment is to prevent a relapse in BD episo...

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BioChem - ISSN 2673-6411