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Diabetology, Volume 4, Issue 4

2023 December - 18 articles

Cover Story: The SGLT-2 inhibitors were initially developed to treat hyperglycemia in people with diabetes. However, it was found in the cardiovascular outcome trials that were FDA-mandated for diabetes that these agents were also helpful for reducing cardiovascular events in people with cardiovascular disease. Further, these agents have been shown to be beneficial in chronic kidney disease both in people with and without diabetes, as well as heart failure in people with and without diabetes. This has transformed this class of medication from being simply an antihyperglycemic agent to being something that would be actively used in cardiology, nephrology, diabetology, and general care. Knowledge of the benefits can improve the quality of life and outcomes for patients with these conditions. View this paper
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Articles (18)

  • Article
  • Open Access
2 Citations
3,803 Views
14 Pages

18 December 2023

Hospitalizations for diabetes and dementia can impose a significant health and economic toll on older adults in the United States. This study sought to examine differences in hospitalization characteristics and outcomes associated with diabetes and d...

  • Article
  • Open Access
4 Citations
3,334 Views
12 Pages

Enrollment, Engagement, and Effectiveness of a Large-Scale Diabetes Prevention Program Using Synchronous Distance Technology

  • Casey Collins,
  • Erin McCallum,
  • Kelly Nordby,
  • Surabhi Aggarwal,
  • Emily Griffith,
  • Cathy Thomas and
  • Carolyn Dunn

11 December 2023

The Centers for Disease Control and Prevention (CDC) indicates that individuals with prediabetes are significantly less likely to develop type 2 diabetes if they participate in a lifestyle change program that results in at least 5% weight loss and 15...

  • Article
  • Open Access
1 Citations
4,249 Views
14 Pages

Global Trends in Risk Factors and Therapeutic Interventions for People with Diabetes and Cardiovascular Disease: Results from the WHO International Clinical Trials Registry Platform

  • Musawenkosi Ndlovu,
  • Phiwayinkosi V. Dludla,
  • Ndivhuwo Muvhulawa,
  • Yonela Ntamo,
  • Asanda Mayeye,
  • Nomahlubi Luphondo,
  • Nokulunga Hlengwa,
  • Albertus K. Basson,
  • Sihle E. Mabhida and
  • Duduzile Ndwandwe
  • + 3 authors

8 December 2023

This study presents a comprehensive analysis of 898 clinical trials conducted between 1999 and 2023, focusing on the interplay of metabolic syndrome, cardiovascular diseases (CVDs), and type 2 diabetes mellitus (T2D). This study draws upon data sourc...

  • Commentary
  • Open Access
2,728 Views
7 Pages

7 December 2023

Similar microorganisms, via similar mechanisms, play a role in the development of both pancreatic cancer (PC) and type 2 diabetes (T2D). Since the new onset of T2D is potentially one of the earliest signs of PC, it is highly plausible that a common d...

  • Review
  • Open Access
5 Citations
7,188 Views
15 Pages

Importance of Dyslipidaemia Treatment in Individuals with Type 2 Diabetes Mellitus—A Narrative Review

  • Dominik Strikić,
  • Andro Vujević,
  • Dražen Perica,
  • Dunja Leskovar,
  • Kristina Paponja,
  • Ivan Pećin and
  • Iveta Merćep

4 December 2023

Type 2 diabetes mellitus (T2DM) is a common metabolic disease characterised by insulin resistance and elevated blood glucose levels, affecting millions of people worldwide. T2DM individuals with dyslipidaemia have an increased risk of cardiovascular...

  • Review
  • Open Access
10 Citations
9,072 Views
10 Pages

Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life Determinant

  • Marija Rogoznica,
  • Dražen Perica,
  • Barbara Borovac,
  • Andrej Belančić and
  • Martina Matovinović

13 November 2023

Type 2 diabetes mellitus (T2DM) is a multisystemic disease with a high global burden and chronic complications. Sexual dysfunction (SD) in patients with T2DM is an often-overlooked complication, despite its high impact on quality of life (QoL). Femal...

  • Communication
  • Open Access
8 Citations
5,182 Views
8 Pages

13 November 2023

An ever-growing body of evidence suggests that sex and gender influence the pathophysiology, incidence, prevalence, clinical manifestations, course, and response to therapy of diabetes. Sex and gender differences are particularly evident in type 1 di...

  • Review
  • Open Access
3 Citations
11,824 Views
12 Pages

13 November 2023

Despite the progress in treatment options and improved understanding of pathophysiology, type 2 diabetes remains one of the costliest and most harmful global chronic diseases. The current guidelines encourage physicians to fight an uphill battle and...

  • Brief Report
  • Open Access
1 Citations
2,383 Views
8 Pages

Educating Medical Students on How to Prescribe Anti-Hyperglycaemic Drugs: A Practical Guide

  • Erik M. Donker,
  • Andrej Belančić,
  • Joost D. Piët,
  • Dinko Vitezić,
  • Jelle Tichelaar and
  • on behalf of the Clinical Pharmacology and Therapeutics Teach the Teacher (CP4T) Program and the Early Career Pharmacologists of the European Association for Clinical Pharmacology and Therapeutics (EACPT)

7 November 2023

In the light of the rapidly increasing global incidence of, and therapeutic arsenal for, diabetes type 2, this brief report underscores the need for advancements in clinical pharmacology and therapeutics (CPT) education with regard to diabetes type 2...

  • Article
  • Open Access
1 Citations
2,206 Views
9 Pages

7 November 2023

Aims: To determine the prevalence and predictors of diabetic retinopathy (DR) in Saudi males and females with diabetes. Methods: This cross-sectional study enrolled 507 patients with diabetes between May and August 2018. The data extracted from patie...

  • Review
  • Open Access
3 Citations
2,928 Views
9 Pages

Recent Advances in Psychotherapeutic Treatment and Understanding of Alexithymia in Patients with Obesity and Diabetes Mellitus Type 2

  • Filip Mustač,
  • Tin Galijašević,
  • Eva Podolski,
  • Andrej Belančić,
  • Martina Matovinović and
  • Darko Marčinko

31 October 2023

Alexithymia is the inability to describe one’s own feelings and is being increasingly researched. According to contemporary psychodynamic theories, negative emotions cannot be adequately named and externalized, but remain trapped in the body. R...

  • Review
  • Open Access
12 Citations
13,264 Views
16 Pages

Diabetes Mellitus—Digital Solutions to Improve Medication Adherence: Scoping Review

  • Nikol Georgieva,
  • Viktor Tenev,
  • Maria Kamusheva and
  • Guenka Petrova

19 October 2023

Medication adherence (MA) is a major problem. On average 50% of chronic disease management medications are not taken as prescribed While digital healthcare tools like mobile apps offer benefits such as informative messages and prescription management...

  • Feature Paper
  • Review
  • Open Access
2,479 Views
12 Pages

Best Practices in the Use of Sodium–Glucose Cotransporter 2 Inhibitors in Diabetes and Chronic Kidney Disease for Primary Care

  • Jay H. Shubrook,
  • Joshua J. Neumiller,
  • Radica Z. Alicic,
  • Tom Manley and
  • Katherine R. Tuttle

19 October 2023

Diabetes is the leading cause of chronic kidney disease (CKD), with nearly half of all cases of kidney failure requiring kidney replacement therapy. While attention is often focused on the profound effects kidney failure has on the quality of life, t...

  • Systematic Review
  • Open Access
3 Citations
4,987 Views
13 Pages

A Systematic Review of Economic Evaluations of Insulin for the Management of Type 2 Diabetes

  • Elvira Meni Maria Gkrinia,
  • Andrea Katrin Faour,
  • Andrej Belančić,
  • Jacques Bazile,
  • Emma Marland and
  • Dinko Vitezić

13 October 2023

Diabetes is a chronic, metabolic disease characterized by hyperglycemia, which occurs as a result of inadequate production or utilization of insulin. Type 2 diabetes (T2D) is the most common type of diabetes with estimates projecting a prevalence of...

  • Article
  • Open Access
10 Citations
6,203 Views
10 Pages

11 October 2023

Type 2 diabetes (T2D) poses a growing global health challenge, impacting patients’ and their caregivers’ well-being. This study investigates the influence of T2D complications on caregivers’ quality of life (QoL) using the WHOQOL-BREF questionnaire,...

  • Communication
  • Open Access
6,418 Views
9 Pages

A Pilot Study on the Glucose-Lowering Effects of a Nutritional Supplement in People with Prediabetes

  • Thrasyvoulos Bemplidakis,
  • Ioanna Eleftheriadou,
  • Ourania Kosta,
  • Konstantinos Tentolouris,
  • Ioanna Anastasiou,
  • Christina Agelaki,
  • Dimitrios Lamprinos,
  • Anastasia Papaioannou,
  • Ioanna Kolovou and
  • Nikolaos Tentolouris
  • + 3 authors

29 September 2023

Background and Objectives: Prediabetes is associated with a high risk of developing diabetes and cardiovascular disease. Early treatment with exercise and dietary interventions can reduce the progression of prediabetes to diabetes or even lead to a r...

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Diabetology - ISSN 2673-4540