2025 December - 22 articles
Quality control of herbal medicinal products (HMPs) is challenging due to their multicomponent composition. For most HMPs, chemical reference standards (CRSs) required for traditional chromatographic and spectral analyses are unavailable. According t...
This paper presents the design and evaluation of a fluorescent probe based on fluorescein hydrazide for the selective detection of hypochlorite (ClO−), bromide (Br−), and iodide (I−) ions in solution. The starting chemosensor, fluor...
Alterations in the expression of the Klotho gene have been associated with chronic kidney disease (CKD), and its potential as an early diagnostic biomarker is currently under active investigation. In this work, we report the development of a highly s...
Waste orange peels (WOP) are a major orange processing residue, and they may be a rich source of precious bioactive polyphenols. Amongst the various WOP constituents, hesperidin holds a prominent position as the most abundant polyphenolic metabolite,...
A probabilistic–deterministic design of experiments (PDDoE) approach was employed to optimize laser-induced breakdown spectroscopy (LIBS) parameters for the quantitative determination of minor components in lead-based alloys. The PDDoE optimiza...
Volatile organic compounds (VOCs) emitted from human skin are promising biomarkers for non-invasive health assessment and disease diagnosis. However, efficient collection and sensitive analytical methods for skin VOCs remain challenging. We developed...
We have developed mold matrices that can be employed to distinguish between enantiomers (D- and L-glucose) and structural isomers (n- and iso-stearic acid) in matrix-assisted laser desorption/ionization mass spectrometry. Utilizing a temperature-resp...
Estrogens are cholesterol-derived hormones, with four endogenous estrogens being presented in the scientific literature, namely, estradiol, estrone, estriol, and estetrol. In this study, we aim to obtain a complete thermoanalytical profile for the th...
Nuts such as pecans, almonds, peanuts, pistachios, and walnuts are nutrient-dense foods rich in unsaturated fatty acids and antioxidant compounds. Their regular consumption has been linked to significant health benefits, including reduced risks of ca...
A high-performance liquid chromatography method coupled with diode array detection (HPLC-DAD) was developed for simultaneous quantification of andrographolide (AG) and 14-deoxy-11,12-didehydroandrographolide (DDAG) in rat plasma. A salt-assisted liqu...
Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants that tend to accumulate in solid matrices such as sewage sludge, raising concerns regarding their fate and potential ecological risks. This study aimed to develop an...
The study evaluated the effect of moderate heating temperatures on physical, mechanical, and spectral properties of bulk flaxseeds and pressed oils. The samples of bulk flaxseeds were measured at 60 mm pressing height and subjected to pretreatment te...
Major vibrational spectroscopy studies have focused on the preparation of chromium coatings via chemical processes (conversion coatings), and few studies have focused on electrochemical processes (electrodeposition). Initially, the chemical precursor...
In modern circular-economy value chains, wood is frequently processed into fines, chips, or powders—forms in which anatomical features are no longer visible, rendering traditional visual identification methods ineffective. This study introduces...
In this study, an integrated analytical method coupling ultra-high-performance liquid chromatography–photodiode array detection–quadrupole time-of-flight mass spectrometry with total antioxidant capacity determination (UHPLC-PDA-Q-TOF/MS-...
In recent years, research and development in the field of green extraction of bioactive compounds from plants has intensified. This increased focus is driven by market trends, environmental concerns, and consumers’ growing interest in natural a...
Wine phenolics serve as robust chemical signatures correlated to grape variety, processing, and regional identity. This study explores the potential of machine learning algorithms, combined with the phenolic profiles of Albanian wines, to classify th...
This study was designed for the analytical method development and validation for Calcium butyrate (CAB) using High-Performance Liquid Chromatography (HPLC). 1H and 13C Nuclear Magnetic Resonance (NMR) and Fourier Transform Infrared (FTIR) spectroscop...
As one of the world’s most widely used packaging materials, paper obtains its properties from its major component: wood. Variations in the species of wood result in variations in the paper’s mechanical properties. The pulp and paper produ...
(1) Background: Caffeine is one of the most widely consumed psychoactive substances. Its safety profile and short half-life make it an ideal drug model for studying the pharmacokinetics of caffeine. This study aimed to develop a method for determinat...
Nucleosides are of significant interest to biomedical and pharmaceutical research and have been successfully separated in hydrophilic interaction liquid chromatography (HILIC). However, there have been few studies focusing on the retention mechanisms...
Significant depletion of natural resources, coupled with increased environmental pollution resulting from the constant evolution of global industrialization, poses a considerable problem. Therefore, it is unsurprising that sustainable “green&rd...
