You are currently viewing a new version of our website. To view the old version click .
  • Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.
  • Case Report
  • Open Access

15 August 2018

2-Year Follow-Up of Lung Transplantation as a Treatment of Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu Disease)

,
,
and
1
Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Medical University of Silesia in Katowice, Silesian Centre for Heart Diseases, Zabrze, Poland
2
Department of Pharmacology, School of Medicine with the Division of Dentistry in Zabrze, Zabrze, Poland
*
Author to whom correspondence should be addressed.

Abstract

Hemorrhagic telangiectasia (HHT) is a disease of initially mild course - manifesting with recurrent nosebleeds and increased fatigue. Nevertheless, its progression can deteriorate patient’s health. Solid organ transplantation becomes the only therapeutic option to save a life. The case report describes a 19-year-old female patient who was diagnosed with HHT and qualified for lung transplantation. She met the Curacao criteria for HHT (¾). Her health deteriorated significantly to the point of the referral to Department of Cardiac, Vascular and Endovascular Surgery and Transplantology in Silesian Center for Heart Diseases. Due to her condition, she was qualified for lung transplantation as one diagnosed with pulmonary arteriovenous malformations and then transplanted at the age of 17. A direct postoperative period was complicated by HSV2 infection of the wound. 18 months after the procedure, the patient underwent acute cholangitis. The presence of portal and systemic fistulas was noted and the final diagnosis of HHT was made. Despite the fact that proper diagnosis was made posttransplant, it was a good treatment. The patient is currently 2 years after the lung transplantation and feels good. Lung transplantation is a viable therapeutic option for patients with HHT as there are reports of other patients who have benefited from lung transplantation after other therapeutic options were exhausted.

Article Metrics

Citations

Article Access Statistics

Multiple requests from the same IP address are counted as one view.