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Volume 77
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10.5603/ARM.27831
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Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.
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Review

Flow Cytometric Basophils Activation Test as a Method of Allergy Diagnosis

by
Olga Potapińska
*,
Urszula Demkow
and
Maria Wąsik
Zakład Diagnostyki Laboratoryjnej i Immunologii Klinicznej Wieku Rozwojowego Warszawskiego Uniwersytetu Medycznego, ul. Marszałkowska 24, 00-576 Warszawa, Poland
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2009, 77(2), 152-158; https://doi.org/10.5603/ARM.27831
Submission received: 26 June 2008 / Revised: 16 March 2009 / Accepted: 16 March 2009 / Published: 16 March 2009

Abstract

For several years the incidences of allergic diseases and anaphylactic reactions have been increasing dramatically. Classical method of allergy diagnosis—skin prick test in some situations can provoke life-threatening reactions. Detection of allergen-induced basophil activation by flow cytometry has been shown to be a useful tool for allergy diagnosis in those patients. CD 63 and CD203c have recently been demonstrated as a specific activation markers of basophils that are rapidly up-regulated after allergen challenge in sensitized patients. Although flow-cytometry methods are quite sophisticated and expensive, it could be a good alternative in patients at risk of severe anaphylactic reactions or with contradictory test results.
Keywords: flow cytometry; basophils; CD63; CD203c; allergy flow cytometry; basophils; CD63; CD203c; allergy

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MDPI and ACS Style

Potapińska, O.; Demkow, U.; Wąsik, M. Flow Cytometric Basophils Activation Test as a Method of Allergy Diagnosis. Adv. Respir. Med. 2009, 77, 152-158. https://doi.org/10.5603/ARM.27831

AMA Style

Potapińska O, Demkow U, Wąsik M. Flow Cytometric Basophils Activation Test as a Method of Allergy Diagnosis. Advances in Respiratory Medicine. 2009; 77(2):152-158. https://doi.org/10.5603/ARM.27831

Chicago/Turabian Style

Potapińska, Olga, Urszula Demkow, and Maria Wąsik. 2009. "Flow Cytometric Basophils Activation Test as a Method of Allergy Diagnosis" Advances in Respiratory Medicine 77, no. 2: 152-158. https://doi.org/10.5603/ARM.27831

APA Style

Potapińska, O., Demkow, U., & Wąsik, M. (2009). Flow Cytometric Basophils Activation Test as a Method of Allergy Diagnosis. Advances in Respiratory Medicine, 77(2), 152-158. https://doi.org/10.5603/ARM.27831

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