Microwave Accelerates the Synthesis of 1-Amidoalkyl-2-Naphthols Using Cu2(NH2-BDC)2(DABCO)-Sal-Co(II) as a Heterogeneous Catalyst †
Research Laboratory of Green Organic Synthesis & Polymers, Department of Chemistry, Iran University of Science and Technology, P.O. Box 16846-13114 Tehran, Iran
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Presented at the 22nd International Electronic Conference on Synthetic Organic Chemistry, 15 November– 15 December 2018; Available Online: https://sciforum.net/conference/ecsoc-22.
Proceedings 2019, 9(1), 68; https://doi.org/10.3390/ecsoc-22-05698
Published: 14 November 2018
(This article belongs to the Proceedings of 22nd International Electronic Conference on Synthetic Organic Chemistry)
Multicomponent reactions have attracted significant attention since they are performed without the need to isolate any intermediate during their process; this diminishes the time and saves both energy and raw materials [1,2]. Derivatives of 1-Amidoalkyl-2-naphthol are of importance, as they can be easily converted to biologically active compounds through amide hydrolysis reaction [3]. Recently, various catalysts have been used to prepare these compounds through a multicomponent reaction. In this research, metal–organic frameworks (MOFs) were utilized as heterogeneous catalysts. They are often crystalline solids consisting of metal ions or clusters coordinated to mostly rigid organic linkers such as aromatic polycarboxylates or polyamines to form one-, two-, or three-dimensional porous structures [4]. We report a green and convenient method for the synthesis of 1-amidoalkyl-2-naphthols from the reaction between β-naphthol, aromatic aldehydes, and amide derivatives under microwave irradiation in the presence of Cu2(NH2-BDC)2(DABCO)-Sal-Co(II) as a modified catalyst through a post-synthesis method. (Scheme 1).
Cu2(NH2-BDC)2(DABCO) was synthesized and then modified with salicylaldehyde and cobalt acetate (II) salt by the ball-milling technique.
References
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Scheme 1.
Synthesis of 1-Amidoalkyl-2-naphthol derivatives catalyzed by metal–organic frameworks (MOFs).
Scheme 1.
Synthesis of 1-Amidoalkyl-2-naphthol derivatives catalyzed by metal–organic frameworks (MOFs).
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MDPI and ACS Style
Panahi, L.; Naimi-Jamal, M.R. Microwave Accelerates the Synthesis of 1-Amidoalkyl-2-Naphthols Using Cu2(NH2-BDC)2(DABCO)-Sal-Co(II) as a Heterogeneous Catalyst. Proceedings 2019, 9, 68. https://doi.org/10.3390/ecsoc-22-05698
AMA Style
Panahi L, Naimi-Jamal MR. Microwave Accelerates the Synthesis of 1-Amidoalkyl-2-Naphthols Using Cu2(NH2-BDC)2(DABCO)-Sal-Co(II) as a Heterogeneous Catalyst. Proceedings. 2019; 9(1):68. https://doi.org/10.3390/ecsoc-22-05698
Chicago/Turabian StylePanahi, Leila, and M. Reza Naimi-Jamal. 2019. "Microwave Accelerates the Synthesis of 1-Amidoalkyl-2-Naphthols Using Cu2(NH2-BDC)2(DABCO)-Sal-Co(II) as a Heterogeneous Catalyst" Proceedings 9, no. 1: 68. https://doi.org/10.3390/ecsoc-22-05698
