Next Article in Journal
Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance
Previous Article in Journal
Percutaneous Coronary Intervention Mortality, Cost, Complications, and Disparities after Radiation Therapy: Artificial Intelligence-Augmented, Cost Effectiveness, and Computational Ethical Analysis
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
JCDD
Volume 10
Issue 11
10.3390/jcdd10110446
jcdd-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Role of ECLS in Managing Post-Myocardial Infarction Ventricular Septal Rupture

by
Rodrigo Sandoval Boburg
1,*,†,
Stoyan Kondov
2,3,†,
Mladen Karamitev
3,
Christian Schlensak
1,
Rafal Berger
1,
Helene Haeberle
4,
Walter Jost
1,
Albi Fagu
2,3,
Friedhelm Beyersdorf
2,3,
Maximilian Kreibich
2,3,
Martin Czerny
2,3 and
Matthias Siepe
2,3,5
1
Department of Thoracic and Cardiovascular Surgery, University Hospital Tübingen, 72076 Tübingen, Germany
2
Department of Cardiovascular Surgery, University Heart Center Freiburg-Bad Krozingen, 79106 Freiburg, Germany
3
Medical Faculty, Albert-Ludwigs-University Freiburg, 79106 Freiburg, Germany
4
Department of Anesthesiology and Critical Care Medicine, University Hospital Tübingen, 72076 Tübingen, Germany
5
Department of Heart Surgery, Cardiovascular Center, Inselspital, 3010 Bern, Switzerland
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
J. Cardiovasc. Dev. Dis. 2023, 10(11), 446; https://doi.org/10.3390/jcdd10110446
Submission received: 2 October 2023 / Revised: 25 October 2023 / Accepted: 28 October 2023 / Published: 30 October 2023
(This article belongs to the Topic Mechanical Circulatory Support in Heart Failure)
Browse Figures
Versions Notes

Abstract

Objectives: The aim of this study was to analyze outcomes in patients undergoing surgery for ventricular septal rupture (VSR) after myocardial infarction (MI) and the preoperative use of extracorporeal life support (ECLS) as a bridge to surgery. Methods: We included patients undergoing surgery for VSR from January 2009 until June 2021 from two centers in Germany. Patients were separated into two groups, those with and without ECLS, before surgery. Pre- and intraoperative data, outcome, and survival during follow-up were evaluated. Results: A total of 47 consecutive patients were included. Twenty-five patients were in the ECLS group, and 22 were in the group without ECLS. All the ECLS-group patients were in cardiogenic shock preoperatively. Most patients in the ECLS group were transferred from another hospital [n = 21 (84%) vs. no-ECLS (n = 12 (57.1%), p = 0.05]. We observed a higher number of postoperative bleeding complications favoring the group without ECLS [n = 6 (28.6%) vs. n = 16 (64%), p < 0.05]. There was no significant difference in the persistence of residual ventricular septal defect (VSD) between groups [ECLS n = 4 (16.7%) and no-ECLS n = 3 (13.6%)], p = 1.0. Total in-hospital mortality was 38.3%. There was no significant difference in in-hospital mortality [n = 6 (27.3%) vs. n = 12 (48%), p = 0.11] and survival at last follow-up between the groups (p = 0.50). Conclusion: We detected no statistical difference in the in-hospital and long-term mortality in patients who received ECLS as supportive therapy after MI-induced VSR compared to those without ECLS. ECLS could be an effective procedure applied as a bridge to surgery in patients with VSR and cardiogenic shock.
Keywords: ECLS; myocardial infarction; ventricular septal rupture ECLS; myocardial infarction; ventricular septal rupture

Share and Cite

MDPI and ACS Style

Sandoval Boburg, R.; Kondov, S.; Karamitev, M.; Schlensak, C.; Berger, R.; Haeberle, H.; Jost, W.; Fagu, A.; Beyersdorf, F.; Kreibich, M.; et al. Role of ECLS in Managing Post-Myocardial Infarction Ventricular Septal Rupture. J. Cardiovasc. Dev. Dis. 2023, 10, 446. https://doi.org/10.3390/jcdd10110446

AMA Style

Sandoval Boburg R, Kondov S, Karamitev M, Schlensak C, Berger R, Haeberle H, Jost W, Fagu A, Beyersdorf F, Kreibich M, et al. Role of ECLS in Managing Post-Myocardial Infarction Ventricular Septal Rupture. Journal of Cardiovascular Development and Disease. 2023; 10(11):446. https://doi.org/10.3390/jcdd10110446

Chicago/Turabian Style

Sandoval Boburg, Rodrigo, Stoyan Kondov, Mladen Karamitev, Christian Schlensak, Rafal Berger, Helene Haeberle, Walter Jost, Albi Fagu, Friedhelm Beyersdorf, Maximilian Kreibich, and et al. 2023. "Role of ECLS in Managing Post-Myocardial Infarction Ventricular Septal Rupture" Journal of Cardiovascular Development and Disease 10, no. 11: 446. https://doi.org/10.3390/jcdd10110446

APA Style

Sandoval Boburg, R., Kondov, S., Karamitev, M., Schlensak, C., Berger, R., Haeberle, H., Jost, W., Fagu, A., Beyersdorf, F., Kreibich, M., Czerny, M., & Siepe, M. (2023). Role of ECLS in Managing Post-Myocardial Infarction Ventricular Septal Rupture. Journal of Cardiovascular Development and Disease, 10(11), 446. https://doi.org/10.3390/jcdd10110446

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop