Anti-Inflammatory and Antioxidative Phytogenic Substances against Secret Killers in Poultry: Current Status and Prospects
Abstract
:Simple Summary
Abstract
1. Introduction
2. Oxidative Stress
2.1. Reactive Species
2.2. Endogenous Antioxidants
2.3. Imbalance between Free Radicals and Antioxidants
2.4. Biomarkers of Oxidative Stress
3. Factors for Oxidative Stress and Inflammation in Poultry: Secret Killers
3.1. Heat Stress
3.2. Dysbiosis
3.3. Mycotoxins
3.4. Diet-Mediated Oxidative Stress
4. Anti-Inflammatory Plants and Their Active Components
4.1. Polyphenols
Antioxidant | Dose | Main Findings | Reference |
---|---|---|---|
Cinnamon bark essential oil | Commercial broilers supplemented with 300 mg/kg |
| [147] |
Condensed tannins from grape seed extract | Commercial broilers supplemented with 125, 250, 500, 1000 and 2000 mg/kg for 42 days |
| [148] |
Eucalytus leaves extract | Layers supplemented with 0.8 g/kg. Birds suffered from acute ethanol-induced oxidative damage conditions |
| [149] |
Resveratrol from Polygonum cuspidatum | Heat-stressed broilers supplemented 350 and 500 mg/kg for seven days (from 28 to 42 days old) |
| [150] |
Resveratrol | Heat-stressed commercial broiler supplemented with 0.2, 0.4 and 0.6 g/kg |
| [151] |
Salix spp. | Heat-stressed commercial broilers supplemented with 0.025% and 0.05% in their diet |
| [152] |
Turmeric rhizome extract | Commercial broilers supplemented with 0.1–0.3 g/kg |
| [153] |
Grape Proanthocyanidins | Commercial broilers supplemented with 7.5, 15 and 30 mg/kg for 42 days |
| [154] |
4.2. Triterpenes
4.3. Anti-Inflammatory and Antioxidant Phytogenic Feed Additives Used in Poultry
4.3.1. Boswellia Extracts
4.3.2. Cannabis
4.3.3. Capsaicin
4.3.4. Cinnamaldehyde
4.3.5. Curcumin
4.3.6. Ginger Extracts
4.3.7. Piperamides
4.3.8. Salix Extracts
4.3.9. Thyme
5. Challenges and Future Prospects
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Mycotoxin | Downregulation of Intracellular Antioxidants | Upregulation of Pro-Inflammatory Cytokines |
---|---|---|
AFB1 | Nrf2, CAT, GPx; SOD | Cytokines, NO; NO2 |
DON | CAT, GPx; SOD | AP-1; ERK-MAPK |
OTA | Nrf2, CAT, GPx; SOD | Fenton reaction |
ZEN | CAT, GPx; SOD | CoX-2, cytokines; iNOS |
T-2 | Nrf2, CAT, GPx, GPx; SOD | Cytokines, iNOS; NO |
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Basiouni, S.; Tellez-Isaias, G.; Latorre, J.D.; Graham, B.D.; Petrone-Garcia, V.M.; El-Seedi, H.R.; Yalçın, S.; El-Wahab, A.A.; Visscher, C.; May-Simera, H.L.; et al. Anti-Inflammatory and Antioxidative Phytogenic Substances against Secret Killers in Poultry: Current Status and Prospects. Vet. Sci. 2023, 10, 55. https://doi.org/10.3390/vetsci10010055
Basiouni S, Tellez-Isaias G, Latorre JD, Graham BD, Petrone-Garcia VM, El-Seedi HR, Yalçın S, El-Wahab AA, Visscher C, May-Simera HL, et al. Anti-Inflammatory and Antioxidative Phytogenic Substances against Secret Killers in Poultry: Current Status and Prospects. Veterinary Sciences. 2023; 10(1):55. https://doi.org/10.3390/vetsci10010055
Chicago/Turabian StyleBasiouni, Shereen, Guillermo Tellez-Isaias, Juan D. Latorre, Brittany D. Graham, Victor M. Petrone-Garcia, Hesham R. El-Seedi, Sakine Yalçın, Amr Abd El-Wahab, Christian Visscher, Helen L. May-Simera, and et al. 2023. "Anti-Inflammatory and Antioxidative Phytogenic Substances against Secret Killers in Poultry: Current Status and Prospects" Veterinary Sciences 10, no. 1: 55. https://doi.org/10.3390/vetsci10010055