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Current Advances in Pediatric Onset Multiple Sclerosis

1
Baylor College of Medicine, Texas Children’s Hospital, Houston, TX 77030, USA
2
Baylor College of Medicine, Maxine Mesinger Multiple Sclerosis Center, Houston, TX 77030, USA
*
Author to whom correspondence should be addressed.
Biomedicines 2020, 8(4), 71; https://doi.org/10.3390/biomedicines8040071
Received: 10 March 2020 / Revised: 25 March 2020 / Accepted: 26 March 2020 / Published: 28 March 2020
(This article belongs to the Special Issue Multiple Sclerosis: Diagnosis and Treatment II)
Multiple sclerosis (MS) is an autoimmune inflammatory disease affecting the central nervous system leading to demyelination. MS in the pediatric population is rare, but has been shown to lead to significant disability over the duration of the disease. As we have learned more about pediatric MS, there has been a development of improved diagnostic criteria leading to earlier diagnosis, earlier initiation of disease-modifying therapies (DMT), and an increasing number of DMT used in the treatment of pediatric MS. Over time, treatment with DMT has trended towards the initiation of higher efficacy treatment at time of diagnosis to help prevent further disease progression and accrual of disability over time, and there is evidence in current literature that supports this change in treatment patterns. In this review, we discuss the current knowledge in diagnosis, treatment, and clinical outcomes in pediatric MS. View Full-Text
Keywords: multiple sclerosis; pediatric multiple sclerosis; neuroimmunology; demyelinating disease; pediatric neurology; child neurology multiple sclerosis; pediatric multiple sclerosis; neuroimmunology; demyelinating disease; pediatric neurology; child neurology
MDPI and ACS Style

Fisher, K.S.; Cuascut, F.X.; Rivera, V.M.; Hutton, G.J. Current Advances in Pediatric Onset Multiple Sclerosis. Biomedicines 2020, 8, 71.

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