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Journal of Developmental Biology, Volume 13, Issue 2

June 2025 - 11 articles

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Articles (11)

  • Article
  • Open Access
1,862 Views
20 Pages

Cannabinoid Receptor 1 Regulates Zebrafish Renal Multiciliated Cell Development via cAMP Signaling

  • Thanh Khoa Nguyen,
  • Sophia Baker,
  • Julienne Angtuaco,
  • Liana Arceri,
  • Samuel Kaczor,
  • Bram Fitzsimonds,
  • Matthew R. Hawkins and
  • Rebecca A. Wingert

Endocannabinoid signaling plays a significant role in neurogenesis and nervous system physiology, but its roles in the development of other tissues are just beginning to be appreciated. Previous reports have shown the presence of the key endocannabin...

  • Article
  • Open Access
1 Citations
4,501 Views
13 Pages

Ribosome Incorporation Transdifferentiates Chick Primary Cells and Induces Their Proliferation by Secreting Growth Factors

  • Shota Inoue,
  • Arif Istiaq,
  • Anamika Datta,
  • Mengxue Lu,
  • Shintaro Nakayama,
  • Kousei Takashi,
  • Nobushige Nakajo,
  • Shigehiko Tamura,
  • Ikko Kawashima and
  • Kunimasa Ohta

Previously, we reported that mammalian cells, specifically human dermal fibroblasts (HDFs), could be transdifferentiated by lactic acid bacteria (LAB). Later, we observed that HDFs incorporated LAB-derived ribosomes, forming the ribosome-induced cell...

  • Article
  • Open Access
1,839 Views
12 Pages

Keratins and keratin-associated proteins (KRTAPs) are the main components of mammalian nails and hair. Comparative genomics and gene expression studies have revealed that keratins are conserved in all vertebrates, whereas KRTAPs exist only in mammals...

  • Article
  • Open Access
2,761 Views
20 Pages

In Vitro Embryo Culture Impacts Heart Mitochondria in Male Adolescent Sheep

  • Reza Amanollahi,
  • Stacey L. Holman,
  • Ashley S. Meakin,
  • Monalisa Padhee,
  • Kimberley J. Botting-Lawford,
  • Song Zhang,
  • Severence M. MacLaughlin,
  • David O. Kleemann,
  • Simon K. Walker and
  • Jennifer M. Kelly
  • + 5 authors

Assisted reproductive technology (ART)such as in vitro embryo culture (IVC), is widely used in human infertility treatments; however, its long-term effects on the cardiac health of offspring remain unclear. This study aimed to determine whether the e...

  • Article
  • Open Access
1 Citations
1,808 Views
14 Pages

Dynamic Changes of Immunoreactive CD34, CD117, and CD41 Hematopoietic Stem Cells in Human Placentas of Different Gestational Ages

  • Sanja Jovicic,
  • Ivan R. Nikolic,
  • Ljiljana Amidžić,
  • Vesna Ljubojevic,
  • Maja Barudzija and
  • Ranko Skrbic

Background: The process of prenatal hematopoiesis occurs in various anatomical locations, including the placenta. The placenta is not merely a temporary hematopoietic reservoir, but it is one of the key sites for the synthesis of hematopoietic stem c...

  • Article
  • Open Access
1 Citations
1,861 Views
18 Pages

Probe Sequencing Analysis of Regenerating Lizard Tails Indicates Crosstalk Among Osteoclasts, Epidermal Cells, and Fibroblasts

  • Darian J. Gamble,
  • Samantha Lopez,
  • Melody Yazdi,
  • Toni Castro-Torres and
  • Thomas P. Lozito

Lizards are distinguished as the only amniotes, and closest relatives of mammals, capable of multilineage epimorphic regeneration. Tail blastemas of green anole lizards (Anolis carolinensis) consist of col3a1+ fibroblastic connective tissue cells enc...

  • Article
  • Open Access
1,814 Views
12 Pages

Follicular Fluid from Cows That Express Estrus During a Fixed-Time Artificial Insemination Protocol Promotes Blastocyst Development

  • Audra W. Harl,
  • Verónica M. Negrón-Pérez,
  • Jacob W. Stewart,
  • George A. Perry,
  • Alan D. Ealy and
  • Michelle L. Rhoads

25 April 2025

It is not yet understood why cows that exhibit estrus and ovulate are more likely to become pregnant than those that ovulate but do not exhibit estrus during a fixed-time artificial insemination (FTAI) protocol. The objective of this work was to dete...

  • Perspective
  • Open Access
3,128 Views
16 Pages

Origins of Aortic Coarctation: A Vascular Smooth Muscle Compartment Boundary Model

  • Christina L. Greene,
  • Geoffrey Traeger,
  • Akshay Venkatesh,
  • David Han and
  • Mark W. Majesky

18 April 2025

Compartment boundaries divide the embryo into segments with distinct fates and functions. In the vascular system, compartment boundaries organize endothelial cells into arteries, capillaries, and veins that are the fundamental units of a circulatory...

  • Article
  • Open Access
2 Citations
1,038 Views
15 Pages

14 April 2025

Molecules involved in the activation of regeneration in reptiles are almost unknown. MARCK-like proteins are indicated to activate regeneration in some amphibians and fish, and it would be important to know whether this is a general process also pres...

  • Review
  • Open Access
3,458 Views
18 Pages

Super-Enhancers in Placental Development and Diseases

  • Gracy X. Rosario,
  • Samuel Brown,
  • Subhradip Karmakar,
  • Mohammad A. Karim Rumi and
  • Nihar R. Nayak

The proliferation of trophoblast stem (TS) cells and their differentiation into multiple lineages are pivotal for placental development and functions. Various transcription factors (TFs), such as CDX2, EOMES, GATA3, TFAP2C, and TEAD4, along with thei...

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J. Dev. Biol. - ISSN 2221-3759