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PIN2 Polarity Establishment in Arabidopsis in the Absence of an Intact Cytoskeleton

by 1,2,†, 1,2 and 1,*
1
Institute of Science and Technology Austria (IST Austria), 3400 Klosterneuburg, Austria
2
Department of Experimental Plant Biology, Faculty of Science, Charles University, 12844 Prague, Czech Republic
*
Author to whom correspondence should be addressed.
Current address: VIB-UGent Center for Plant Systems Biology, 9052 Ghent, Belgium.
Biomolecules 2019, 9(6), 222; https://doi.org/10.3390/biom9060222
Received: 3 May 2019 / Revised: 5 June 2019 / Accepted: 5 June 2019 / Published: 7 June 2019
(This article belongs to the Special Issue Advances in Molecular Biology of Action of Auxins)
Cell polarity is crucial for the coordinated development of all multicellular organisms. In plants, this is exemplified by the PIN-FORMED (PIN) efflux carriers of the phytohormone auxin: The polar subcellular localization of the PINs is instructive to the directional intercellular auxin transport, and thus to a plethora of auxin-regulated growth and developmental processes. Despite its importance, the regulation of PIN polar subcellular localization remains poorly understood. Here, we have employed advanced live-cell imaging techniques to study the roles of microtubules and actin microfilaments in the establishment of apical polar localization of PIN2 in the epidermis of the Arabidopsis root meristem. We report that apical PIN2 polarity requires neither intact actin microfilaments nor microtubules, suggesting that the primary spatial cue for polar PIN distribution is likely independent of cytoskeleton-guided endomembrane trafficking. View Full-Text
Keywords: cell polarity; polarity establishment; PIN auxin efflux carriers; cytoskeleton; actin; microtubules; live-cell imaging cell polarity; polarity establishment; PIN auxin efflux carriers; cytoskeleton; actin; microtubules; live-cell imaging
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MDPI and ACS Style

Glanc, M.; Fendrych, M.; Friml, J. PIN2 Polarity Establishment in Arabidopsis in the Absence of an Intact Cytoskeleton. Biomolecules 2019, 9, 222.

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