Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016).
Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence.
Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
Sci. Pharm. 2010, 78(4), 897-908; https://doi.org/10.3797/scipharm.1003-19 (registering DOI)
Polyphenols from Ginkgo biloba
Faculty of Pharmacy, Petra University, Airport Street, P O Box 961343 Amman, Jordan
Institut fuer pharmazeutische Biologie und Phytochemie, Hittorfstrasse 56, D-48149 Muenster, Germany
HerbResearch, Wartbergweg 15, D-86874 Mattsies, Germany
School of Pharmacy, Al-Ahliyya Amman University: Amman-19328, Jordan
Author to whom correspondence should be addressed.
Received: 23 March 2010 / Accepted: 28 October 2010 / Published: 28 October 2010
PDF [241 KB, uploaded 12 October 2016]
Abstract By Sephadex LH-20 gel chromatography of an extract from Gingko biloba leaves, polymeric proanthocyanidins were eluted after the fractions of flavonol glycosides and biflavone glycosides. A purified proanthocyanidin polymer accounted for 86.6% of the total proanthocyanidins, and for 37.7% of the total antioxidant activity of this leaf extract. For structure elucidation, the polymer was submitted to acidic depolymerization in the presence of phloroglucinol. The structures of the resulting flavan-3-ols and phloroglucinol adducts were determined on the basis of 1D-and reverse 2D-NMR (HSQC, HMBC) spectra of their peracetylated derivatives, MALDI-TOF-MS and CD-spectroscopy. The observations resulting from the degradation with phloroglucinol were confirmed by 13C-NMR spectroscopy of the polymer. The mean molecular weight of the polymeric fraction was estimated to be 9–10 flavan-3-ol-units.
This is an open access article distributed under the Creative Commons Attribution License
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
Share & Cite This Article
MDPI and ACS Style
QA’DAN, F.; NAHRSTEDT, A.; SCHMIDT, M.; MANSOOR, K. Polyphenols from Ginkgo biloba. Sci. Pharm. 2010, 78, 897-908.
QA’DAN F, NAHRSTEDT A, SCHMIDT M, MANSOOR K. Polyphenols from Ginkgo biloba. Scientia Pharmaceutica. 2010; 78(4):897-908.
QA’DAN, Fadi; NAHRSTEDT, Adolf; SCHMIDT, Mathias; MANSOOR, Kenza. 2010. "Polyphenols from Ginkgo biloba." Sci. Pharm. 78, no. 4: 897-908.
Show more citation formats
Show less citations formats
[Return to top]
For more information on the journal statistics, click here
Multiple requests from the same IP address are counted as one view.