Next Issue
Volume 75, December
Previous Issue
Volume 75, June
Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).

Table of Contents

Sci. Pharm., Volume 75, Issue 3 (September 2007) – 3 articles , Pages 97-146

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Readerexternal link to open them.
Order results
Result details
Select all
Export citation of selected articles as:
Open AccessArticle
Antiproliferative activity of selected medicinal plants of Jordan against a breast adenocarcinoma cell line (MCF7)
Sci. Pharm. 2007, 75(3), 121-146; https://doi.org/10.3797/scipharm.2007.75.121 - 28 Sep 2007
Cited by 67 | Viewed by 1514
Abstract
76 ethanolic extracts of medicinal herbs from the Jordanian flora, belonging to 67 species and 34 families, were evaluated for their antiproliferative activity on a breast cancer cell line (MCF7). The cells were cultured in RPMI 1640 medium and incubated with the extracts [...] Read more.
76 ethanolic extracts of medicinal herbs from the Jordanian flora, belonging to 67 species and 34 families, were evaluated for their antiproliferative activity on a breast cancer cell line (MCF7). The cells were cultured in RPMI 1640 medium and incubated with the extracts for 72 hours. Sulphorhodamine B (SRB) assay was used to test cytotoxicity.
From the tested crude extracts, Inula graveolens, Salvia dominica, Conyza canadiensis and Achillea santolina showed potent antiproliferative activity and the activity resided in the chloroform/ethanolic extracts. The most active plant was I. graveolens with an IC50 of 3.83 μg/ml. Phytochemical screening indicated the presence of flavonoids, terpenoids, and phenolics in all active extracts. These results indicate the possible potential use of medicinal plants from the Jordanian flora as antineoplastic agents. Full article
Open AccessArticle
Two New Saponins from Solidago gigantea
Sci. Pharm. 2007, 75(3), 111-120; https://doi.org/10.3797/scipharm.2007.75.111 - 28 Sep 2007
Cited by 3 | Viewed by 703
Abstract
Two new triterpenoid saponins, named giganteasaponin 5 and giganteasaponin 6, were isolated from the aboveground parts of Solidago gigantea and were defined to be 3-O-[β-D-Apio-D-furanosyl-(1→3)- β-D-glucopyranosyl-(1→3)- β-D-glucopyranosyl]- 28-O {α-L-rhamnopyranosyl-(1→3)- β-D-xylopyranosyl-(1→4)- [β-D-xylopyranosyl-( 1→3)]- α-L-rhamnopyranosyl-(1→2) [α-L-rhamnopyranosyl-(1→3)]- β-Dxylopyranosyl}- Bayogenin respectively 3-O- [β-D-Apio-D-furanosyl-(1→3)- β-Dgluco- pyranosyl-(1→3)- β-D-glucopyranosyl]-28-O {β-D-galactopyranosyl-(1→2)- [...] Read more.
Two new triterpenoid saponins, named giganteasaponin 5 and giganteasaponin 6, were isolated from the aboveground parts of Solidago gigantea and were defined to be 3-O-[β-D-Apio-D-furanosyl-(1→3)- β-D-glucopyranosyl-(1→3)- β-D-glucopyranosyl]- 28-O {α-L-rhamnopyranosyl-(1→3)- β-D-xylopyranosyl-(1→4)- [β-D-xylopyranosyl-( 1→3)]- α-L-rhamnopyranosyl-(1→2) [α-L-rhamnopyranosyl-(1→3)]- β-Dxylopyranosyl}- Bayogenin respectively 3-O- [β-D-Apio-D-furanosyl-(1→3)- β-Dgluco- pyranosyl-(1→3)- β-D-glucopyranosyl]-28-O {β-D-galactopyranosyl-(1→2)- α- L-rhamnopyranosyl-(1→3)- β-D-xylopyranosyl-(1→4)- [β-D-xylopyranosyl-(1→3)]- α-L-rhamnopyranosyl-(1→2) [α-L-rhamnopyranosyl-(1→3)]- β-D-xylopyranosyl}- Bayogenin. The structures were established on the basis of chemical degradation, extensive MS studies and NMR investigations as well. Full article
Open AccessArticle
In Vitro Release Studies on Multiple and Simple Emulsions of α-Tocopherol with Pistacia Leaves
Sci. Pharm. 2007, 75(3), 97-110; https://doi.org/10.3797/scipharm.2007.75.97 - 28 Sep 2007
Cited by 4 | Viewed by 521
Abstract
α-Tocopherol is the most effective lipid soluble natural antioxidant and free-radical scavenger. The present study aimed to evaluate the performance of the extracts of Pistacia lentiscus, P. lentiscus var. chia and P. terebinthus leaves as additives on in vitro release of α-tocopherol. [...] Read more.
α-Tocopherol is the most effective lipid soluble natural antioxidant and free-radical scavenger. The present study aimed to evaluate the performance of the extracts of Pistacia lentiscus, P. lentiscus var. chia and P. terebinthus leaves as additives on in vitro release of α-tocopherol. The α-tocopherol content of Pistacia extracts were determined and the release was investigated from w/o/w multiple emulsion, w/o and o/w simple emulsions through cellulose acetate and cellulose nitrate membranes by using HPLC-UV method. As significant increase in the extent of α-tocopherol release was observed with the addition of Pistacia extracts in all emulsions. They could be suggested as suitable additives in α-tocopherol containing formulations. Full article
Previous Issue
Next Issue
Back to TopTop