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Diseases, Volume 12, Issue 11

2024 November - 35 articles

Cover Story: Hypertension (HTN) affects more than 60% of individuals aged older than 65 years representing a major risk factor for cardiovascular diseases and playing a crucial role for approximately 8.5 million deaths from ischemic heart disease, renal and vascular disorders. HTN affects cerebral functions leading to the so-called cerebral small vessel disease (CSVD), a disorder characterized by lesions on small arteries, capillaries, arterioles and venules. CSVD is to a great extent asymptomatic, however, microbleeds, microinfarcts or lacunes in the brain can accumulate over time and increase the risk of stroke, dementia, depression and mobility disorders. It is already known that HTN is strongly linked with CSVD, however, there is room for further research to better understand their close relationship. View this paper
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Articles (35)

  • Article
  • Open Access
4 Citations
3,520 Views
10 Pages

Efficiency of IL-6 in Early Prognosis and Follow-Up in Critically Ill Patients with Septic Shock

  • Yenifer Gamarra-Morales,
  • Jorge Molina-López,
  • Felipe-Carlos Santiago-Ruiz,
  • Lourdes Herrera-Quintana,
  • Héctor Vázquez-Lorente,
  • Félix Gascón-Luna and
  • Elena Planells

20 November 2024

Background/Objectives: The aim of this study was to investigate the response of interleukin-6 (IL-6) during the first few hours of a patient’s stay in the Intensive Care Unit (ICU) in a sample of critically ill patients with septic shock, compa...

  • Case Report
  • Open Access
2 Citations
2,046 Views
9 Pages

20 November 2024

Background: Optimal medical therapy (OMT) is increasingly recognized as a cornerstone in managing chronic coronary syndrome (CCS), offering a non-invasive alternative to percutaneous coronary intervention (PCI). Case Presentation: A 38-year-old male...

  • Article
  • Open Access
5 Citations
2,194 Views
15 Pages

19 November 2024

Background/Objectives: Tuberculosis (TB) remains a significant global health challenge, with drug-resistant tuberculosis (DR-TB) posing a greater threat due to difficulty in treatment. This study aimed to investigate the relationship between comorbid...

  • Systematic Review
  • Open Access
2 Citations
2,863 Views
13 Pages

Comparison of the Safety and Efficacy of Ustekinumab and Vedolizumab in Patients with Crohn’s Disease: A Systematic Review and Meta-Analysis of Propensity Score Matched Cohort Studies

  • Andrea Pasta,
  • Francesco Calabrese,
  • Elisa Marabotto,
  • Manuele Furnari,
  • Maria Giulia Demarzo,
  • Raffaele Pellegrino,
  • Antonietta Gerarda Gravina,
  • Alessandro Federico,
  • Edoardo Giovanni Giannini and
  • Giorgia Bodini

19 November 2024

Background: Ustekinumab and vedolizumab represent both valid therapeutic options in patients with Crohn’s Disease. Data comparing the safety and efficacy of these drugs are indirect, with conflicting results reported. We aim to conduct a system...

  • Article
  • Open Access
1 Citations
1,635 Views
12 Pages

The Promotion of Non-Communicable Disease Screening in Gurage Zone, Ethiopia: A Mixed-Method Study

  • Heldana Debebe,
  • Bezawit Ketema,
  • Sophie Sarah Rossner,
  • Sarah Negash,
  • Adamu Addissie,
  • Mirgissa Kaba,
  • Mulugeta Tamire and
  • Eva Johanna Kantelhardt

17 November 2024

Background: Despite the high non-communicable disease (NCD) mortality in Ethiopia, NCD screening in the country remains suboptimal. This study assessed the health communication process and materials designed to promote NCD screening among adult prima...

  • Systematic Review
  • Open Access
2,836 Views
24 Pages

15 November 2024

Background: Long-COVID, which might develop after a SARS-CoV-2 infection, is a rather new disease without standardized treatment strategies. A large number of approaches that integrate physical activity have been described in the literature, and this...

  • Article
  • Open Access
6 Citations
5,355 Views
21 Pages

14 November 2024

Family caregivers of people with neuropsychiatric conditions are at risk of caregiver burden and declining health. The aims of this study were to identify the impact of caring on long-term family caregivers and their unmet needs and to explore their...

  • Systematic Review
  • Open Access
1,593 Views
10 Pages

Association Between Retinol-Binding Protein 4 Levels and Hepatitis C Virus Infection: A Meta-Analysis

  • Yingying Lin,
  • Xinyu Cui,
  • Na Zhu,
  • Yanyan Li,
  • Peng Wang,
  • Xin Wang,
  • Yunyun Yi and
  • Xin Li

13 November 2024

Background and Objectives: The relationship between circulating retinol-binding protein 4 (RBP4) levels and hepatitis C virus (HCV) infection remains unclear. This study aims to systematically assess RBP4 expression in patients with HCV and its corre...

  • Case Report
  • Open Access
1 Citations
2,298 Views
9 Pages

12 November 2024

Background: This case report details the innovative use of selective internal radiation therapy (SIRT) with Yttrium-90 resin microspheres to treat a 73-year-old woman with a solitary fibrous tumor (SFT), a rare and challenging tumor type. SFTs often...

  • Article
  • Open Access
6 Citations
1,690 Views
22 Pages

Exploring Sex-Based Neuropsychological Outcomes in Pediatric Brain Cancer Survivors: A Pilot Study

  • Chiara Colliva,
  • Veronica Rivi,
  • Pierfrancesco Sarti,
  • Isabel Cobelli and
  • Johanna M. C. Blom

11 November 2024

Background: The increasing survival rates among pediatric cancer patients underscore the critical need to understand the long-term psychosocial impacts of cancer treatments, such as cisplatin and carboplatin. While these treatments are lifesaving, th...

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Diseases - ISSN 2079-9721