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J. Clin. Med. 2019, 8(4), 480;

A New Surgical Site Infection Risk Score: Infection Risk Index in Cardiac Surgery

Cardiac Surgery, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, Spain
Anatomy and Radiology, Pharmacology and Therapeutics, Faculty of Medicine, University of Valladolid, 47003 Valladolid, Spain
Nephrology, Hospital Virgen de la Concha, 49022 Zamora, Spain
Prevention and Control of Infection, Hospital Universitario de La Princesa, 28006 Madrid, Spain
Author to whom correspondence should be addressed.
Received: 17 March 2019 / Revised: 3 April 2019 / Accepted: 4 April 2019 / Published: 9 April 2019
(This article belongs to the Section Cardiology)
PDF [662 KB, uploaded 19 April 2019]
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Various scoring systems attempt to predict the risk of surgical site infection (SSI) after cardiac surgery, but their discrimination is limited. Our aim was to analyze all SSI risk factors in both coronary artery bypass graft (CABG) and valve replacement patients in order to create a new SSI risk score for such individuals. A priori prospective collected data on patients that underwent cardiac surgery (n = 2020) were analyzed following recommendations from the Reporting of studies Conducted using Observational Routinely collected health Data (RECORD) group. Study participants were divided into two periods: the training sample for defining the new tool (2010–2014, n = 1298), and the test sample for its validation (2015–2017, n = 722). In logistic regression, two preoperative variables were significantly associated with SSI (odds ratio (OR) and 95% confidence interval (CI)): diabetes, 3.3/2–5.7; and obesity, 4.5/2.2–9.3. The new score was constructed using a summation system for punctuation using integer numbers, that is, by assigning one point to the presence of either diabetes or obesity. The tool performed better in terms of assessing SSI risk in the test sample (area under the Receiver-Operating Characteristic curve (aROC) and 95% CI, 0.67/055–0.76) compared to the National Nosocomial Infections Surveillance (NNIS) risk index (0.61/0.50–0.71) and the Australian Clinical Risk Index (ACRI) (0.61/0.50–0.72). A new two-variable score to preoperative SSI risk stratification of cardiac surgery patients, named Infection Risk Index in Cardiac surgery (IRIC), which outperforms other classical scores, is now available to surgeons. Personalization of treatment for cardiac surgery patients is needed. View Full-Text
Keywords: surgical site infection; patient outcome; cardiac surgical procedures; scoring systems surgical site infection; patient outcome; cardiac surgical procedures; scoring systems

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Bustamante-Munguira, J.; Herrera-Gómez, F.; Ruiz-Álvarez, M.; Hernández-Aceituno, A.; Figuerola-Tejerina, A. A New Surgical Site Infection Risk Score: Infection Risk Index in Cardiac Surgery. J. Clin. Med. 2019, 8, 480.

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