Next Article in Journal
A Comparison of the Social-Adaptive Perspective and Functionalist Perspective on Guilt and Shame
Next Article in Special Issue
Effectiveness of a Computer-Based Training Program of Attention and Memory in Patients with Acquired Brain Damage
Previous Article in Journal
Challenging Notions of Academic Entitlement and Its Rise among Liberal Arts College Students
Previous Article in Special Issue
Creating a World-Class Program through Training and Certification
Open AccessPerspective

Non-Clinical Models for Neurodegenerative Diseases: Therapeutic Approach and Drug Validation in Animal Models

Basic Division, International Center of Neurological Restoration (CIREN), Havana 11300, Cuba
Medical Surgical Research Center (CIMEQ), Faculty of Medical Sciences Victoria de Giron, Havana 11300, Cuba
Cuban Society of Laboratory Animal Science (SCCAL), Veterinary Council Presidency, Havana 10400, Cuba
Author to whom correspondence should be addressed.
Behav. Sci. 2017, 7(4), 82;
Received: 22 November 2017 / Revised: 28 November 2017 / Accepted: 29 November 2017 / Published: 7 December 2017
(This article belongs to the Special Issue State of Art in Non-Clinical Models for Neurodegenerative Diseases)
PDF [212 KB, uploaded 7 December 2017]


In 2016, 19.8% of the Cuban population was aged 60 or over. As a result, age-associated degenerative diseases and other diseases have become priority targets from a prophylactic, diagnostic and therapeutic perspective. As a result, the Cuban biomedical scientific community has addressed its basic, preclinical and epidemiological research in order to rise up to the challenge. A firm step in this direction has been the international congress “State of the art in non-clinical models for neurodegenerative diseases” which has brought together preclinical and clinical researchers, technicians and regulatory staff members from different countries to review the state of the art in neurodegenerations, find unifying ideas, objectives and collaborations or partnership. The objective is to expose the perspectives of new biotechnological products from Cuba and other countries from the diagnostic, therapeutic and neuroprotective point of view. It is crucial, therefore, that the irreplaceable role of laboratory animals in achieving these objectives is understood but they must be used in rational, adequate and ethical manner. We expose the current development trends in this field, being of common interest to the work directed to the search for potential drugs, diagnostic tools and the promotion of changes in lifestyle as a preventive projection. View Full-Text
Keywords: animal model; behavior; neurodegenerative disease; neuroprotection; Ciren animal model; behavior; neurodegenerative disease; neuroprotection; Ciren
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Fernandez, C.I.; López, J.; Martinez, L. Non-Clinical Models for Neurodegenerative Diseases: Therapeutic Approach and Drug Validation in Animal Models. Behav. Sci. 2017, 7, 82.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Behav. Sci. EISSN 2076-328X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top