Skip Content
You are currently on the new version of our website. Access the old version .

Medical Sciences, Volume 7, Issue 8

2019 August - 6 articles

Cover Story: This review will highlight the insights gained into the neuroendocrine mechanisms underlying PCOS, focusing primarily on data gleaned from preclinical animal models of PCOS. First, we will briefly introduce the various PCOS animal models and summarize their neuroendocrine reproductive traits, focusing on gonadotropin and sex steroid levels. Following that, we will review recent findings on brain and neuroendocrine alterations at the cellular, molecular, and physiological levels, in various PCOS research models, and discuss how this may relate to the human PCOS condition. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (6)

  • Review
  • Open Access
4 Citations
4,644 Views
6 Pages

9 August 2019

Traditionally, it was thought that the pathogenesis of erectile dysfunction (ED) can be divided into psychological and organic factors. However, recent literature supports the development and progression of ED due to multidimensional alterations of a...

  • Review
  • Open Access
15 Citations
5,354 Views
13 Pages

5 August 2019

Multi-parametric magnetic resonance imaging (mpMRI) and positron emission tomography (PET) using prostate-specific membrane antigen (PSMA) targeting ligands have been adopted as a new standard of imaging modality in the management of prostate cancer...

  • Review
  • Open Access
23 Citations
8,306 Views
8 Pages

Origins and Impact of Psychological Traits in Polycystic Ovary Syndrome

  • Elisabet Stener-Victorin,
  • Maria Manti,
  • Romina Fornes,
  • Sanjiv Risal,
  • Haojiang Lu and
  • Anna Benrick

5 August 2019

Women with polycystic ovary syndrome (PCOS) exhibit compromised psychiatric health. Independent of obesity, women with PCOS are more susceptible to have anxiety and depression diagnoses and other neuropsychiatric disorders. During pregnancy women wit...

  • Review
  • Open Access
89 Citations
22,009 Views
16 Pages

2 August 2019

Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder, affecting at least 10% of women of reproductive age. PCOS is typically characterized by the presence of at least two of the three cardinal features of hyperandrogenemia (hi...

  • Review
  • Open Access
32 Citations
6,747 Views
14 Pages

Immunotherapies and Targeted Therapies in the Treatment of Metastatic Colorectal Cancer

  • Prashanth Rawla,
  • Adam Barsouk,
  • Andreas V. Hadjinicolaou and
  • Alexander Barsouk

Colorectal cancer (CRC) is the third leading cause of cancer deaths, and while mortality has largely improved in the developed world, five-year survival for metastatic disease remains dismally low at only 15%. Fortunately, nearly a dozen targeted the...

  • Article
  • Open Access
17 Citations
5,822 Views
14 Pages

TRPV1 Antagonists as Novel Anti-Diabetic Agents: Regulation of Oral Glucose Tolerance and Insulin Secretion Through Reduction of Low-Grade Inflammation?

  • Dorte X. Gram,
  • Josefine Fribo,
  • Istvan Nagy,
  • Carsten Gotfredsen,
  • Ana Charrua,
  • John B. Hansen,
  • Anker J. Hansen and
  • Arpad Szallasi

With a global prevalence among adults over 18 years of age approaching 9%, Type 2 diabetes mellitus (T2DM) has reached pandemic proportions and represents a major unmet medical need. To date, no disease modifying treatment is available for T2DM patie...

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Med. Sci. - ISSN 2076-3271