Dietary Supplementation of Honey Bee Larvae with Arginine and Abscisic Acid Enhances Nitric Oxide and Granulocyte Immune Responses after Trauma

INRA Centre de Recherche Provence-Alpes-Côted’Azur, Unitè Abeilles et Environnement, UMR PrADE, Domaine Saint Paul, Site Agroparc, Avignon F-84914, France

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Insects 2017, 8(3), 85; https://doi.org/10.3390/insects8030085

Received: 24 May 2017 / Revised: 18 July 2017 / Accepted: 5 August 2017 / Published: 15 August 2017

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Abstract

Many biotic and abiotic stressors impact bees’ health, acting as immunosupressors and contribute to colony losses. Thus, the importance of studying the immune response of honey bees is central to develop new strategies aiming to enhance bees’ fitness to confront the threats affecting them. If a pathogen breaches the physical and chemical barriers, honey bees can protect themselves from infection with cellular and humoral immune responses which represent a second line of defense. Through a series of correlative studies we have previously reported that abscisic acid (ABA) and nitric oxide (NO) share roles in the same immune defenses of Apis mellifera (A. mellifera). Here we show results supporting that the supplementation of bee larvae’s diet reared in vitro with l-Arginine (precursor of NO) or ABA enhanced the immune activation of the granulocytes in response to wounding and lipopolysaccharide (LPS) injection. View Full-Text

Keywords: Apis mellifera; abscisic acid; nitric oxide; immune response

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MDPI and ACS Style

Negri, P.; Ramirez, L.; Quintana, S.; Szawarski, N.; Maggi, M.; Le Conte, Y.; Lamattina, L.; Eguaras, M. Dietary Supplementation of Honey Bee Larvae with Arginine and Abscisic Acid Enhances Nitric Oxide and Granulocyte Immune Responses after Trauma. Insects 2017, 8, 85. https://doi.org/10.3390/insects8030085

AMA Style

Negri P, Ramirez L, Quintana S, Szawarski N, Maggi M, Le Conte Y, Lamattina L, Eguaras M. Dietary Supplementation of Honey Bee Larvae with Arginine and Abscisic Acid Enhances Nitric Oxide and Granulocyte Immune Responses after Trauma. Insects. 2017; 8(3):85. https://doi.org/10.3390/insects8030085

Chicago/Turabian Style

Negri, Pedro, Leonor Ramirez, Silvina Quintana, Nicolás Szawarski, Matías Maggi, Yves Le Conte, Lorenzo Lamattina, and Martin Eguaras. 2017. "Dietary Supplementation of Honey Bee Larvae with Arginine and Abscisic Acid Enhances Nitric Oxide and Granulocyte Immune Responses after Trauma" Insects 8, no. 3: 85. https://doi.org/10.3390/insects8030085

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Dietary Supplementation of Honey Bee Larvae with Arginine and Abscisic Acid Enhances Nitric Oxide and Granulocyte Immune Responses after Trauma

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