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The Search for Biomarkers in Fibromyalgia

Department of Internal Medicine, Division of Rheumatology, Dell Medical School at the University of Texas at Austin, 1601 Trinity St, Austin, TX 78712, USA
Academic Editor: Jeng-Hsien Yen
Diagnostics 2021, 11(2), 156; https://doi.org/10.3390/diagnostics11020156
Received: 10 January 2021 / Accepted: 18 January 2021 / Published: 21 January 2021
(This article belongs to the Special Issue Rheumatic Diseases: Diagnosis, Treatment and Management)
Fibromyalgia is the most common of the central sensitivity syndromes affecting 2–5% of the adult population in the United States. This pain amplification syndrome has enormous societal impact as measured by work absenteeism, decreased work productivity, disability and injury compensation and over-utilization of healthcare resources. Multiple studies have shown that early diagnosis of this condition can improve patient outlook and redirect valuable healthcare resources towards more appropriate targeted therapy. Efforts have been made towards improving diagnostic accuracy through updated criteria. The search for biomarkers for diagnosis and verification of Fibromyalgia is an ongoing process. Inadequacies with current diagnostic criteria for this condition have fueled these efforts for identification of a reproducible marker that can verify this disease in a highly sensitive, specific and reproducible manner. This review focuses on areas of research for biomarkers in fibromyalgia and suggests that future efforts might benefit from approaches that utilize arrays of biomarkers to identify this disorder that presents with a diverse clinical phenotype. View Full-Text
Keywords: fibromyalgia; vibrational spectroscopy; biomarker; cytokines; central sensitization fibromyalgia; vibrational spectroscopy; biomarker; cytokines; central sensitization
MDPI and ACS Style

Hackshaw, K.V. The Search for Biomarkers in Fibromyalgia. Diagnostics 2021, 11, 156. https://doi.org/10.3390/diagnostics11020156

AMA Style

Hackshaw KV. The Search for Biomarkers in Fibromyalgia. Diagnostics. 2021; 11(2):156. https://doi.org/10.3390/diagnostics11020156

Chicago/Turabian Style

Hackshaw, Kevin V. 2021. "The Search for Biomarkers in Fibromyalgia" Diagnostics 11, no. 2: 156. https://doi.org/10.3390/diagnostics11020156

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Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

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