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Article

Bone Structure Analysis of the Radius Using Ultrahigh Field (7T) MRI: Relevance of Technical Parameters and Comparison with 3T MRI and Radiography

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Department of Radiology, Massachusetts General Hospital, Harvard University, Boston, MA 02114, USA
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Department of Radiology, Friedrich Alexander University Erlangen-Nürnberg (FAU) & Universitätsklinikum Erlangen, 91054 Erlangen, Germany
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Department of Radiology, Brigham and Women’s Hospital, Harvard University, Boston, MA 02114, USA
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Medical Physics in Radiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany
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Department of Epidemiology and Biostatistics, University of California San Francisco (UCSF), San Francisco, CA 94143, USA
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Department of Radiology, Boston University School of Medicine, Boston, MA 02118, USA
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Department of Radiology, Boston Veteran Affairs Healthcare System, West Roxbury, MA 02132, USA
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Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology, University Medical Center Rostock, D-18057 Rostock, Germany
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Department of Plastic and Hand Surgery, Friedrich Alexander University Erlangen-Nürnberg (FAU) & Universitätsklinikum Erlangen, 91054 Erlangen, Germany
*
Author to whom correspondence should be addressed.
Diagnostics 2021, 11(1), 110; https://doi.org/10.3390/diagnostics11010110
Received: 22 December 2020 / Revised: 6 January 2021 / Accepted: 6 January 2021 / Published: 12 January 2021
(This article belongs to the Special Issue Advanced MRI Techniques for Musculoskeletal Imaging)
Bone fractal signature analysis (FSA—also termed bone texture analysis) is a tool that assesses structural changes that may relate to clinical outcomes and functions. Our aim was to compare bone texture analysis of the distal radius in patients and volunteers using radiography and 3T and 7T magnetic resonance imaging (MRI)—a patient group (n = 25) and a volunteer group (n = 25) were included. Participants in the patient group had a history of chronic wrist pain with suspected or confirmed osteoarthritis and/or ligament instability. All participants had 3T and 7T MRI including T1-weighted turbo spin echo (TSE) sequences. The 7T MRI examination included an additional high-resolution (HR) T1 TSE sequence. Radiographs of the wrist were acquired for the patient group. When comparing patients and volunteers (unadjusted for gender and age), we found a statistically significant difference of horizontal and vertical fractal dimensions (FDs) using 7T T1 TSE-HR images in low-resolution mode (horizontal: p = 0.04, vertical: p = 0.01). When comparing radiography to the different MRI sequences, we found a statistically significant difference for low- and high-resolution horizontal FDs between radiography and 3T T1 TSE and 7T T1 TSE-HR. Vertical FDs were significantly different only between radiographs and 3T T1 TSE in the high-resolution mode; FSA measures obtained from 3T and 7T MRI are highly dependent on the sequence and reconstruction resolution used, and thus are not easily comparable between MRI systems and applied sequences. View Full-Text
Keywords: bone structure; wrist; MRI; X-ray; fractal signature analysis bone structure; wrist; MRI; X-ray; fractal signature analysis
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MDPI and ACS Style

Jarraya, M.; Heiss, R.; Duryea, J.; Nagel, A.M.; Lynch, J.A.; Guermazi, A.; Weber, M.-A.; Arkudas, A.; Horch, R.E.; Uder, M.; Roemer, F.W. Bone Structure Analysis of the Radius Using Ultrahigh Field (7T) MRI: Relevance of Technical Parameters and Comparison with 3T MRI and Radiography. Diagnostics 2021, 11, 110. https://doi.org/10.3390/diagnostics11010110

AMA Style

Jarraya M, Heiss R, Duryea J, Nagel AM, Lynch JA, Guermazi A, Weber M-A, Arkudas A, Horch RE, Uder M, Roemer FW. Bone Structure Analysis of the Radius Using Ultrahigh Field (7T) MRI: Relevance of Technical Parameters and Comparison with 3T MRI and Radiography. Diagnostics. 2021; 11(1):110. https://doi.org/10.3390/diagnostics11010110

Chicago/Turabian Style

Jarraya, Mohamed, Rafael Heiss, Jeffrey Duryea, Armin M. Nagel, John A. Lynch, Ali Guermazi, Marc-André Weber, Andreas Arkudas, Raymund E. Horch, Michael Uder, and Frank W. Roemer 2021. "Bone Structure Analysis of the Radius Using Ultrahigh Field (7T) MRI: Relevance of Technical Parameters and Comparison with 3T MRI and Radiography" Diagnostics 11, no. 1: 110. https://doi.org/10.3390/diagnostics11010110

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