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Multifunctional Nanofibers towards Active Biomedical Therapeutics

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Department of Chemistry and Biochemistry, Lamar University, P.O. Box 10009, Beaumont, TX 77710, USA
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Materials Engineering And Nanosensor (MEAN) Laboratory, Dan F. Smith Department of Chemical Engineering, Lamar University, P.O. Box 10053, Beaumont, TX 77710, USA
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Integrated Composites Laboratory (ICL), Dan F. Smith Department of Chemical Engineering, Lamar University, P.O. Box 10053, Beaumont, TX 77710, USA
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Authors to whom correspondence should be addressed.
Academic Editor: Russell Gorga
Polymers 2015, 7(2), 186-219; https://doi.org/10.3390/polym7020186
Received: 8 November 2014 / Revised: 11 December 2014 / Accepted: 23 January 2015 / Published: 3 February 2015
One-dimensional (1-D) nanostructures have attracted enormous research interest due to their unique physicochemical properties and wide application potential. These 1-D nanofibers are being increasingly applied to biomedical fields owing to their high surface area-to-volume ratio, high porosity, and the ease of tuning their structures, functionalities, and properties. Many biomedical nanofiber reviews have focused on tissue engineering and drug delivery applications but have very rarely discussed their use as wound dressings. However, nanofibers have enormous potential as wound dressings and other clinical applications that could have wide impacts on the treatment of wounds. Herein, the authors review the main fabrication methods of nanofibers as well as requirements, strategies, and recent applications of nanofibers, and provide perspectives of the challenges and opportunities that face multifunctional nanofibers for active therapeutic applications. View Full-Text
Keywords: multifunctional; nanofibers; biomedical; therapeutics; electrospun; clinical multifunctional; nanofibers; biomedical; therapeutics; electrospun; clinical
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Sharma, J.; Lizu, M.; Stewart, M.; Zygula, K.; Lu, Y.; Chauhan, R.; Yan, X.; Guo, Z.; Wujcik, E.K.; Wei, S. Multifunctional Nanofibers towards Active Biomedical Therapeutics. Polymers 2015, 7, 186-219.

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