Next Article in Journal
Composition, Structural Evolution and the Related Property Variations in Preparation of Mixed Cesium/Ammonium Acidic Salts of Heteropolyacids
Next Article in Special Issue
Unconventional Approaches Involving Cyclodextrin-Based, Self-Assembly-Driven Processes for the Conversion of Organic Substrates in Aqueous Biphasic Catalysis
Previous Article in Journal
Untangling the Role of the Capping Agent in Nanocatalysis: Recent Advances and Perspectives
Open AccessArticle

Chitosan Aerogel Catalyzed Asymmetric Aldol Reaction in Water: Highly Enantioselective Construction of 3-Substituted-3-hydroxy-2-oxindoles

by 1,2, 2, 1,* and 2,*
1
School of Chemical Engineering, Sichuan University, Chengdu 610065, China
2
State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu 610041, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Luca Gonsalvi
Catalysts 2016, 6(12), 186; https://doi.org/10.3390/catal6120186
Received: 3 October 2016 / Revised: 10 November 2016 / Accepted: 21 November 2016 / Published: 28 November 2016
(This article belongs to the Special Issue Homogeneous Catalysis and Mechanisms in Water and Biphasic Media)
A chitosan aerogel catalyzed asymmetric aldol reaction of ketones with isatins in the presence of water is described. This protocol was found to be environmentally benign, because it proceeds smoothly in water and the corresponding aldol products were obtained in excellent yields with good enantioselectivities. View Full-Text
Keywords: chitosan aerogel; aldol reaction; water; isatin chitosan aerogel; aldol reaction; water; isatin
Show Figures

Graphical abstract

MDPI and ACS Style

Dong, H.; Liu, J.; Ma, L.; Ouyang, L. Chitosan Aerogel Catalyzed Asymmetric Aldol Reaction in Water: Highly Enantioselective Construction of 3-Substituted-3-hydroxy-2-oxindoles. Catalysts 2016, 6, 186.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map

1
Back to TopTop