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Review
Peer-Review Record

Transcriptional Condensates: Epigenetic Reprogramming and Therapeutic Targets in Hematologic Malignancies

Cancers 2025, 17(19), 3148; https://doi.org/10.3390/cancers17193148
by Kevin Qiu 1, Qing Yin 1, Chongzhi Zang 2 and Jianguo Tao 1,*
Reviewer 1:
Reviewer 2: Anonymous
Cancers 2025, 17(19), 3148; https://doi.org/10.3390/cancers17193148
Submission received: 19 August 2025 / Revised: 21 September 2025 / Accepted: 25 September 2025 / Published: 27 September 2025

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

refer to attachment

Comments for author File: Comments.pdf

Comments on the Quality of English Language

requires significant corrections. Professional help can be considered.

Author Response

Please see the attachment

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

The review of Qiu, Yin, and Tao is comprehensively written, round, and easy to understand. It gives a complete understanding of the role of transcriptional condensates.

Minor things to consider:

Although transcriptional condensates have a role in tumor initiation and progression, there are several other factors needed. Therefore, I would suggest to milden their CENTRAL role in carcinogenesis.

Page 3, line 133: Is there a verb missing from this sentence “… a repetitive, unstructured, low-complexity region that also an IDR”?

The function of TCs is repeated too many times.

Author Response

Please see the attachment

Author Response File: Author Response.pdf

Round 2

Reviewer 1 Report

Comments and Suggestions for Authors

no further comments

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