Difference Between Walking Parameters During 6 Min Walk Test Before and After Abdominal Surgery in Colorectal Cancer Patients
Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Participants
2.3. Study Protocol
2.4. Outcome Measurement
2.5. Statistical Analysis
3. Results
Differences Between Groups
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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N = 72 | |||
---|---|---|---|
n | % | ||
Gender | Male | 47 | 65.3 |
Female | 25 | 34.7 | |
Age | Younger than 60 | 26 | 36.11 |
Between 60 and 75 | 40 | 55.5 | |
Older than 75 | 6 | 8.33 | |
Localization of tumor | Right colon | 17 | 23.6 |
Left colon | 24 | 33.3 | |
Rectum | 31 | 43.1 | |
Metastatic disease | No | 55 | 76.4 |
Yes | 17 | 23.6 | |
BMI | Underweight | 0 | 0 |
Normal | 19 | 26.39 | |
Overweight | 27 | 37.5 | |
Obese | 26 | 36.11 | |
Other diagnoses | Arterial hypertension | 40 | 55.5 |
Diabetes mellitus type 2 | 13 | 18.1 | |
Ischemic heart disease | 7 | 9.7 | |
Other oncologic diagnosis | 16 | 22.2 | |
Cardiovascular drugs | Beta blocker | 16 | 22.2 |
Calcium channel blocker | 13 | 1821 | |
ACE inhibitors | 28 | 38.9 | |
Weight loss | Yes | 26 | 36.11 |
No | 46 | 63.89 | |
Digestive symptoms | Diarrhea | 12 | 16.67 |
Nausea | 2 | 2.78 | |
Constipation | 10 | 13.89 | |
Bleeding | 1 | 1.39 | |
No symptoms | 47 | 65.3 | |
Neoadjuvant therapy before surgery | No | 60 | 83.3 |
Chemotherapy/radiotherapy | 8 | 11.11 | |
Chemotherapy | 3 | 4.17 | |
Radiotherapy | 1 | 1.39 | |
Surgery procedure | Right colectomy | 14 | 19.45 |
Left colectomy | 7 | 9.72 | |
Low anterior resection of rectum | 14 | 19.45 | |
Segmental resection of colon | 18 | 25 | |
Sec. Hartman | 5 | 6.95 | |
Subtotal colectomy | 3 | 4.17 | |
Abdominoperitoneal extirpation of the rectum | 3 | 4.17 | |
Transanal | 3 | 4.17 | |
Other | 5 | 6.95 | |
Duration of surgical procedure | Less than 2 h | 26 | 36.11 |
Between 2 and 3 h | 35 | 48.61 | |
Longer than 3 h | 11 | 15.27 | |
Intensity of physical activity before surgery (workplace or free-time activity) | No physical activity (<1.5 METS) | 5 | 6.94 |
Light (<3 METs) | 35 | 48.61 | |
Medium (z6METs) | 22 | 30.55 | |
High (>1METs) | 10 | 13.89 |
Global Health Status | Functional Scales | QoR 15 | |||||||
---|---|---|---|---|---|---|---|---|---|
Physical | Role | Emotional | Cognitive | Social | |||||
Mean | 63.63 | 95.38 | 96.13 | 96.45 | 92.01 | 98.58 | 135.76 | ||
SD | 18.31 | 9.15 | 7.21 | 14.48 | 13.54 | 6.84 | 9.35 | ||
QLQ C-30 Before Surgery | |||||||||
Symptoms | |||||||||
Fatigue | Nausea and Vomiting | Pain | Dyspnea | Insomnia | Appetite Loss | Constipation | Diarrhea | Financial Difficulties | |
Mean | 5.94 | 1.64 | 5.4 | 5.32 | 10.65 | 5.33 | 11.54 | 9.68 | 1.05 |
SD | 12.48 | 7.54 | 11.59 | 15.54 | 22.8 | 18.33 | 27.61 | 23.48 | 8.96 |
Minimum | Maximum | Mean | Range | SD | p-Value | |
---|---|---|---|---|---|---|
Maximal heart rate before surgery | 57 | 121 | 96.85 | 64 | 13.01 | p < 0.05 |
Maximal heart rate after surgery | 77 | 151 | 107.3 | 74 | 13.44 | |
Average heart rate before surgery | 51 | 114 | 88.75 | 63 | 12.66 | p < 0.05 |
Average heart rate after surgery | 61 | 125 | 97.79 | 64 | 12.12 | |
Maximal speed before surgery (km/h) | 4.18 | 7.72 | 5.57 | 3.54 | 0.52 | p < 0.05 |
Maximal speed after surgery (km/h) | 2.42 | 7.89 | 5.15 | 5.47 | 0.71 | |
Average speed before surgery (km/h) | 1.93 | 7.24 | 4.36 | 5.3 | 0.51 | p < 0.05 |
Average speed after surgery (km/h) | 0.48 | 6.43 | 3.46 | 5.95 | 0.7 | |
Number of steps before surgery | 399 | 740 | 600.68 | 341 | 65.78 | p < 0.05 |
Number of steps after surgery | 100 | 651 | 485.37 | 551 | 130.61 | |
Walk distance before surgery (meters) | 113 | 580 | 375.45 | 467 | 0.05 | p < 0.05 |
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Santek, N.; Langer, S.; Kirac, I.; Velemir Vrdoljak, D.; Tometic, G.; Musteric, G.; Mayer, L.; Cigrovski Berkovic, M. Difference Between Walking Parameters During 6 Min Walk Test Before and After Abdominal Surgery in Colorectal Cancer Patients. Cancers 2025, 17, 1782. https://doi.org/10.3390/cancers17111782
Santek N, Langer S, Kirac I, Velemir Vrdoljak D, Tometic G, Musteric G, Mayer L, Cigrovski Berkovic M. Difference Between Walking Parameters During 6 Min Walk Test Before and After Abdominal Surgery in Colorectal Cancer Patients. Cancers. 2025; 17(11):1782. https://doi.org/10.3390/cancers17111782
Chicago/Turabian StyleSantek, Nikolina, Sanja Langer, Iva Kirac, Danko Velemir Vrdoljak, Gordan Tometic, Goran Musteric, Ljiljana Mayer, and Maja Cigrovski Berkovic. 2025. "Difference Between Walking Parameters During 6 Min Walk Test Before and After Abdominal Surgery in Colorectal Cancer Patients" Cancers 17, no. 11: 1782. https://doi.org/10.3390/cancers17111782
APA StyleSantek, N., Langer, S., Kirac, I., Velemir Vrdoljak, D., Tometic, G., Musteric, G., Mayer, L., & Cigrovski Berkovic, M. (2025). Difference Between Walking Parameters During 6 Min Walk Test Before and After Abdominal Surgery in Colorectal Cancer Patients. Cancers, 17(11), 1782. https://doi.org/10.3390/cancers17111782