Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women
AbstractAn adequate mineral supply to preterm infants is essential for normal growth and development. This study aimed to compare the mineral contents of human milk (HM) from healthy mothers of preterm (28–32 weeks) and full term (>37 weeks) infants. Samples were collected weekly for eight weeks for the term group (n = 34) and, biweekly up to 16 weeks for the preterm group (n = 27). Iron, zinc, selenium, copper, iodine, calcium, magnesium, phosphorus, potassium, and sodium were quantitatively analyzed by Inductively Coupled Plasma-Mass Spectrometry. The mineral contents of both HM showed parallel compositional changes over the period of lactation, with occasional significant differences when compared at the same postpartum age. However, when the comparisons were performed at an equivalent postmenstrual age, preterm HM contained less zinc and copper from week 39 to 48 (p < 0.002) and less selenium from week 39 to 44 (p < 0.002) than term HM. This translates into ranges of differences (min–max) of 53% to 78%, 30% to 72%, and 11% to 33% lower for zinc, copper, and selenium, respectively. These data provide comprehensive information on the temporal changes of ten minerals in preterm HM and may help to increase the accuracy of the mineral fortification of milk for preterm consumption. View Full-Text
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Sabatier, M.; Garcia-Rodenas, C.L.; De Castro, C.A.; Kastenmayer, P.; Vigo, M.; Dubascoux, S.; Andrey, D.; Nicolas, M.; Richoz Payot, J.; Bordier, V.; Thakkar, S.K.; Beauport, L.; Tolsa, J.-F.; Fischer Fumeaux, C.J.; Affolter, M. Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women. Nutrients 2019, 11, 1855.
Sabatier M, Garcia-Rodenas CL, De Castro CA, Kastenmayer P, Vigo M, Dubascoux S, Andrey D, Nicolas M, Richoz Payot J, Bordier V, Thakkar SK, Beauport L, Tolsa J-F, Fischer Fumeaux CJ, Affolter M. Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women. Nutrients. 2019; 11(8):1855.Chicago/Turabian Style
Sabatier, Magalie; Garcia-Rodenas, Clara L.; De Castro, Carlos A.; Kastenmayer, Peter; Vigo, Mario; Dubascoux, Stéphane; Andrey, Daniel; Nicolas, Marine; Richoz Payot, Janique; Bordier, Valentine; Thakkar, Sagar K.; Beauport, Lydie; Tolsa, Jean-François; Fischer Fumeaux, Céline J.; Affolter, Michael. 2019. "Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women." Nutrients 11, no. 8: 1855.
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