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21,501 Results Found

  • Proceeding Paper
  • Open Access
1,471 Views
5 Pages

Calcium Biofortification in Solanum tuberosum L.: Assessing the Influence of Calcium Nitrate and Calcium Chloride on Yield

  • Ana Rita F. Coelho,
  • Inês Carmo Luís,
  • Ana Coelho Marques,
  • Cláudia Campos Pessoa,
  • Diana Daccak,
  • Carlos Galhano,
  • Manuela Simões,
  • Maria Manuela Silva,
  • Maria F. Pessoa and
  • Fernando C. Lidon
  • + 6 authors

Potato (Solanum tuberosum L.) is a widely consumed and essential food crop globally, making it an ideal food matrix for biofortification. Agronomic biofortification is one of the strategies used to enhance Ca content in edible parts of crops, conside...

  • Review
  • Open Access
193 Citations
23,931 Views
12 Pages

Calcium Intake in Bone Health: A Focus on Calcium-Rich Mineral Waters

  • Letizia Vannucci,
  • Caterina Fossi,
  • Sara Quattrini,
  • Leonardo Guasti,
  • Barbara Pampaloni,
  • Giorgio Gronchi,
  • Francesca Giusti,
  • Cecilia Romagnoli,
  • Luisella Cianferotti and
  • Maria Luisa Brandi
  • + 1 author

5 December 2018

Calcium is an essential element that plays numerous biological functions in the human body, of which one of the most important is skeleton mineralization. Bone is a mineralized connective tissue in which calcium represents the major component, confer...

  • Article
  • Open Access
10 Citations
2,842 Views
15 Pages

Lactobacillus helveticus-Derived Whey-Calcium Chelate Promotes Calcium Absorption and Bone Health of Rats Fed a Low-Calcium Diet

  • Wei Hu,
  • Zhiwen Pei,
  • Aonan Xia,
  • Yang Jiang,
  • Bo Yang,
  • Xiaoming Liu,
  • Jianxin Zhao,
  • Hao Zhang and
  • Wei Chen

11 April 2024

This study investigated the characteristics of Lactobacillus helveticus-derived whey-calcium chelate (LHWCC) and its effect on the calcium absorption and bone health of rats. Fourier-transform infrared spectroscopy showed that carboxyl oxygen atoms,...

  • Review
  • Open Access
21 Citations
11,135 Views
8 Pages

16 September 2010

Osteoporosis is the index disease for calcium deficiency, just as rickets/osteomalacia is the index disease for vitamin D deficiency, but there is considerable overlap between them. The common explanation for this overlap is that hypovitaminosis D ca...

  • Article
  • Open Access
11 Citations
5,875 Views
18 Pages

21 March 2022

Promoting calcium intake is a cornerstone for osteoporosis management. Some individuals limit dairy product consumption, a major calcium source, due to their high content in saturated fats and their perceived negative impact on lipid profiles. This s...

  • Article
  • Open Access
7 Citations
3,097 Views
10 Pages

Associations of Calcium from Food Sources versus Phosphate Binders with Serum Calcium and FGF23 in Hemodialysis Patients

  • Sara Mahdavi,
  • Antonio Bellasi,
  • Karan Nagra,
  • Luke Johnston,
  • Paul Tam,
  • Biagio Di Iorio and
  • Tabo Sikaneta

14 October 2019

Background: Dysregulated serum calcium and FGF23 are associated with increased mortality and morbidity rates in patients receiving hemodialysis. Preliminary data suggest serum calcium regulates FGF23 secretion independently of serum phosphate, parath...

  • Review
  • Open Access
84 Citations
23,659 Views
25 Pages

The Processing of Calcium Rich Agricultural and Industrial Waste for Recovery of Calcium Carbonate and Calcium Oxide and Their Application for Environmental Cleanup: A Review

  • Virendra Kumar Yadav,
  • Krishna Kumar Yadav,
  • Marina M. S. Cabral-Pinto,
  • Nisha Choudhary,
  • Govindhan Gnanamoorthy,
  • Vineet Tirth,
  • Shiv Prasad,
  • Afzal Husain Khan,
  • Saiful Islam and
  • Nadeem A. Khan

6 May 2021

Every year a million tonnes of calcium rich agro and industrial waste are generated around the whole globe. These calcium rich waste like finger citron, shells of cockle, mussel, oysters etc., and egg shell are biological sources which have various o...

  • Article
  • Open Access
2 Citations
2,857 Views
12 Pages

Calcium (Ca) is an essential nutrient element crucial for plant growth and development, especially in tomatoes. This study investigated the effects of foliar spraying with different concentrations (3 g·L−1, 6 g·L−1, 9 g&midd...

  • Article
  • Open Access
16 Citations
8,403 Views
16 Pages

Co-Deposition Mechanisms of Calcium Sulfate and Calcium Carbonate Scale in Produced Water

  • Yan Yan,
  • Tao Yu,
  • Huan Zhang,
  • Jiayu Song,
  • Chengtun Qu,
  • Jinling Li and
  • Bo Yang

1 December 2021

Co-precipitation of mineral-based salts during scaling remains poorly understood and thermodynamically undefined within the water industry. This study focuses on investigating calcium carbonate and calcium sulfate mixed precipitation in scaling. Scal...

  • Feature Paper
  • Article
  • Open Access
23 Citations
4,962 Views
10 Pages

15 July 2022

In this study, calcium carbonate nanoparticles (CCNPs) and calcium oxide nanoparticles (CONPs) are synthesized by the carbonization/calcination of calcium oleate. CONPs are an essential inorganic material, and they are used as catalysts and as effect...

  • Review
  • Open Access
305 Citations
44,684 Views
16 Pages

Calcium Intake and Health

  • Gabriela Cormick and
  • Jose M Belizán

15 July 2019

There are striking inequities in calcium intake between rich and poor populations. Appropriate calcium intake has shown many health benefits, such as reduction of hypertensive disorders of pregnancy, lower blood pressure particularly among young peop...

  • Review
  • Open Access
139 Citations
10,621 Views
13 Pages

Calcium Overload and Mitochondrial Metabolism

  • Lauren L. Walkon,
  • Jasiel O. Strubbe-Rivera and
  • Jason N. Bazil

17 December 2022

Mitochondria calcium is a double-edged sword. While low levels of calcium are essential to maintain optimal rates of ATP production, extreme levels of calcium overcoming the mitochondrial calcium retention capacity leads to loss of mitochondrial func...

  • Article
  • Open Access
2 Citations
1,917 Views
15 Pages

Sirtuin-1 Regulates Mitochondrial Calcium Uptake Through Mitochondrial Calcium Uptake 1 (MICU1)

  • Xinyi Zhang,
  • Shuhu Liu,
  • Yanshan Su,
  • Ling Zhang,
  • Ting Guo and
  • Xuemin Wang

25 January 2025

Mitochondria play a central role in cell biological processes, functioning not only as producers of ATP but also as regulators of Ca2+ signaling. Mitochondrial calcium uptake occurs primarily through the mitochondrial calcium uniporter channel (mtCU)...

  • Article
  • Open Access
5 Citations
4,575 Views
16 Pages

Calcium Ion Deposition with Precipitated Calcium Carbonate: Influencing Factors and Mechanism Exploration

  • Wenhui Feng,
  • Zhi Yee Ng,
  • Han Chen,
  • Jiasong Zhang,
  • Dan Xu,
  • Ying He,
  • Hongyuan Wei and
  • Leping Dang

22 March 2024

In order to apply precipitated calcium carbonate (PCC) in the detergent industry, its ability to deposit calcium ions in hard water is an important process. In this work, the calcium ion deposition in the presence of PCC from different sources is inv...

  • Article
  • Open Access
41 Citations
6,825 Views
20 Pages

11 June 2019

In our current investigation, we evaluated the effect of Chlorella pyrenoidosa protein hydrolysate (CPPH) and Chlorella pyrenoidosa protein hydrolysate-calcium chelate (CPPH-Ca) on calcium absorption and gut microbiota composition, as well as their i...

  • Article
  • Open Access
10 Citations
8,592 Views
16 Pages

Eggshell-Waste-Derived Calcium Acetate, Calcium Hydrogen Phosphate and Corresponding Eggshell Membranes

  • Ivica Strelec,
  • Klara Tomičić,
  • Marko Zajec,
  • Marta Ostojčić and
  • Sandra Budžaki

21 June 2023

The development of innovative transformation techniques for various wastes generated by the agri-food industry is one of the goals of sustainable waste management oriented toward “zero-waste” approach. This includes the production of bulk...

  • Review
  • Open Access
1 Citations
7,107 Views
32 Pages

11 July 2025

Calcium plays a major role in all cellular functions, and its regulation is important in all aspects of human health. This key role calcium plays in cell function can be traced to its unique molecular coordination geometry, which is often overlooked...

  • Article
  • Open Access
3 Citations
2,486 Views
16 Pages

7 April 2024

The homeostasis of cellular calcium is fundamental for many physiological processes, while the calcium levels remain inhomogeneous within cells. During the onset of asthma, epithelial and inflammatory cells secrete platelet-derived growth factor (PDG...

  • Article
  • Open Access
12 Citations
3,566 Views
17 Pages

13 July 2023

This study examined the physicochemical effects of the fortification of noodles with 0.25–1.00% (w/w) calcium salts, viz. calcium acetate, calcium carbonate, calcium citrate, and calcium lactate. Fortification with calcium citrate, calcium acet...

  • Feature Paper
  • Article
  • Open Access
48 Citations
12,563 Views
10 Pages

Microbially induced mineral precipitation is recognized as a widespread phenomenon in nature. A diverse range of minerals including carbonate, sulphides, silicates, and phosphates can be produced through biomineralization. Calcium carbonate (CaCO3) i...

  • Review
  • Open Access
54 Citations
9,201 Views
21 Pages

12 September 2018

As an important second messenger, the calcium ion (Ca2+) plays a vital role in normal brain function and in the pathophysiological process of different neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD...

  • Article
  • Open Access
13 Citations
4,502 Views
13 Pages

16 April 2021

As a major gangue mineral in sulfide ores, talc is difficult to separate from chalcopyrite in the flotation process due to its natural floatability, which affects the subsequent smelting process. In this study, the effects of calcium ions and calcium...

  • Article
  • Open Access
37 Citations
5,523 Views
12 Pages

25 October 2021

With the current study, we aimed to determine the characteristics and calcium absorption capacity of egg white peptide–calcium complex (EWP-Ca) and determine the effect of sterilization on EWP-Ca to study the possibility of EWP-Ca as a new potential...

  • Article
  • Open Access
3 Citations
3,482 Views
11 Pages

18 November 2023

Tomato fruit is an excellent model for evaluating calcium regulation in plants since it expresses symptoms of either calcium deficiency or calcium excess. Aiming to evaluate the structure of the vascular system and its interactions with calcium and c...

  • Article
  • Open Access
4 Citations
2,239 Views
19 Pages

23 November 2023

Store-operated calcium entry (SOCE) in cardiomyocytes may be involved in cardiac remodeling, but the underlying mechanisms remain elusive. We hypothesized that SOCE may increase nuclear calcium, which alters gene expression via calcium/calmodulin-dep...

  • Systematic Review
  • Open Access
39 Citations
23,737 Views
14 Pages

Calcium from Finger Millet—A Systematic Review and Meta-Analysis on Calcium Retention, Bone Resorption, and In Vitro Bioavailability

  • Seetha Anitha,
  • David Ian Givens,
  • Rosemary Botha,
  • Joanna Kane-Potaka,
  • Nur Liana Binti Sulaiman,
  • Takuji W. Tsusaka,
  • Kowsalya Subramaniam,
  • Ananthan Rajendran,
  • Devraj J. Parasannanavar and
  • Raj Kumar Bhandari

4 August 2021

Calcium deficiency during child growth leads to osteoporosis in later stages of life. Finger millet is one of the calcium dense foods, with three times the level of calcium than milk, and the only cereal that contains high calcium content which is co...

  • Review
  • Open Access
1,972 Views
20 Pages

28 November 2024

Recombinant aequorin has been extensively used in mammalian and plant systems as a powerful tool for calcium monitoring. While aequorin has also been widely applied in yeast research, a notable gap exists in the literature regarding comprehensive rev...

  • Review
  • Open Access
2 Citations
1,974 Views
14 Pages

Dysregulated Calcium Handling in Cirrhotic Cardiomyopathy

  • Sang Youn Hwang,
  • Hongqun Liu and
  • Samuel S. Lee

Cirrhotic cardiomyopathy is a syndrome of blunted cardiac systolic and diastolic function in patients with cirrhosis. However, the mechanisms remain incompletely known. Since contractility and relaxation depend on cardiomyocyte calcium transients, an...

  • Article
  • Open Access
6 Citations
3,521 Views
12 Pages

Effects of Calcium Lactate-Enriched Pumpkin on Calcium Status in Ovariectomized Rats

  • Natalia Wawrzyniak,
  • Anna Gramza-Michałowska,
  • Ewa Pruszyńska-Oszmałek,
  • Maciej Sassek and
  • Joanna Suliburska

13 July 2022

This study aimed to evaluate the effects of enriched pumpkin on calcium status in ovariectomized rats. The study was conducted in sixty female Wistar rats, which were divided into six groups: a group fed a standard diet (C) and five ovariectomized gr...

  • Article
  • Open Access
12 Citations
2,086 Views
11 Pages

19 April 2024

To explore the effects of the introduction order of calcium sources and the bacteria-to-calcium ratio on the microbially induced calcium carbonate precipitation (MICP) product CaCO3 and to achieve the regulation of CaCO3 crystal morphology, the miner...

  • Article
  • Open Access
19 Citations
2,758 Views
10 Pages

10 October 2022

In order to study the effect of calcium sulfate whiskers and calcium carbonate whiskers on the road performance of asphalt mixtures, the high temperature stability, low temperature performance, and the change of water stability, the effect of two whi...

  • Article
  • Open Access
1 Citations
1,284 Views
20 Pages

Preparation, Structural Characterization, and Calcium Supplementation Activity of Lycium barbarum Peptide–Calcium Derived from Bovine Bones

  • Long Wang,
  • Jia Cai,
  • Lin Liu,
  • Shunpeng Zhu,
  • Yangxi Chen,
  • Min Xu,
  • Jie Zhong,
  • Jiaxin Li,
  • Liang Zhang and
  • Qiang Ye

7 November 2025

Calcium deficiency is a global public health issue because calcium supplements are consistently inefficient. Although there is a large amount of calcium in bovine bones, its bioactivity is rather low. This study aimed to optimize the extraction proce...

  • Article
  • Open Access
30 Citations
4,435 Views
17 Pages

Process Optimization, Structural Characterization, and Calcium Release Rate Evaluation of Mung Bean Peptides-Calcium Chelate

  • Wenliang Zhai,
  • Dong Lin,
  • Ruoshuang Mo,
  • Xiaozhuan Zou,
  • Yongqing Zhang,
  • Liyun Zhang and
  • Yonghui Ge

2 March 2023

To reduce grievous ecological environment pollution and protein resource waste during mung bean starch production, mung bean peptides-calcium chelate (MBP-Ca) was synthesized as a novel and efficient calcium supplement. Under the optimal conditions (...

  • Article
  • Open Access
3 Citations
2,616 Views
24 Pages

28 October 2022

Unidentified pathogenetic mechanisms and genetic and clinical heterogeneity represent critical factors hindering the development of treatments for inherited retinal dystrophies. Frameshift mutations in Cacna2d4, which codes for an accessory subunit o...

  • Review
  • Open Access
9 Citations
8,967 Views
19 Pages

19 October 2022

Parkinson’s disease (PD) is a neurodegenerative movement disorder characterized by the loss of dopaminergic neurons, which results in motor impairment. The rationale and objective of the review article is to determine whether CCBs use contribut...

  • Article
  • Open Access
9 Citations
6,394 Views
18 Pages

Calcium Phosphate Powder Synthesized from Calcium Acetate and Ammonium Hydrophosphate for Bioceramics Application

  • Tatiana Safronova,
  • Valery Putlayev,
  • Yaroslav Filippov,
  • Tatiana Shatalova,
  • Evgeny Karpushkin,
  • Dmitrii Larionov,
  • Gilyana Kazakova and
  • Yury Shakhtarin

15 December 2018

Calcium phosphate powder was synthesized at room temperature from aqueous solutions of ammonium hydrophosphate and calcium acetate without pH adjusting at constant Ca/P molar ratio 1.5. Phase composition of the as-synthesized powder depended on the p...

  • Article
  • Open Access
11 Citations
3,482 Views
15 Pages

26 February 2024

With the increasing accumulation of alkaline industrial solid waste, the mineralization of CO2 using alkaline industrial solid waste has broad application prospects. Carbide slag is highly alkaline and contains a large amount of calcium elements, mak...

  • Article
  • Open Access
7 Citations
4,881 Views
13 Pages

Evaluation of an Ionic Calcium Fiber Supplement and Its Impact on Bone Health Preservation in a Dietary Calcium Deficiency Mice Model

  • Sara Elisa Herrera-Rodríguez,
  • Eristeo García-Márquez,
  • Eduardo Padilla-Camberos and
  • Hugo Espinosa-Andrews

18 January 2022

Ionic calcium can help in the prevention of the process of osseous decalcification. This study aimed to evaluate the physicochemical properties and toxic effects of ionic calcium-fiber supplement (ICa+) and its impact on bone health preservation in m...

  • Article
  • Open Access
6 Citations
3,031 Views
12 Pages

Bone calcium turnover is aggravated in pregnant women recommended to bed rest. In the present cross-sectional study, we aimed to clarify whether preterm neonates would benefit from calcium supplementation during pregnancy. Forty-two mothers (37.5 &pl...

  • Review
  • Open Access
123 Citations
11,272 Views
14 Pages

The Significance of Calcium in Photosynthesis

  • Quan Wang,
  • Sha Yang,
  • Shubo Wan and
  • Xinguo Li

As a secondary messenger, calcium participates in various physiological and biochemical reactions in plants. Photosynthesis is the most extensive biosynthesis process on Earth. To date, researchers have found that some chloroplast proteins have Ca2+-...

  • Review
  • Open Access
67 Citations
14,657 Views
26 Pages

22 January 2013

Through a systematic search in Pubmed for literature, on links between calcium malnutrition and risk of chronic diseases, we found the highest degree of evidence for osteoporosis, colorectal and breast cancer, as well as for hypertension, as the only...

  • Review
  • Open Access
46 Citations
10,259 Views
25 Pages

Calcium is a highly positively charged ionic species. It regulates all cell types’ functions and is an important second messenger that controls and triggers several mechanisms, including membrane stabilization, permeability, contraction, secret...

  • Review
  • Open Access
75 Citations
19,108 Views
11 Pages

Calcium Channels in the Heart: Disease States and Drugs

  • Kajol Shah,
  • Sarah Seeley,
  • Castin Schulz,
  • Jacqueline Fisher and
  • Shubha Gururaja Rao

10 March 2022

Calcium ions are the major signaling ions in the cells. They regulate muscle contraction, neurotransmitter secretion, cell growth and migration, and the activity of several proteins including enzymes and ion channels and transporters. They participat...

  • Article
  • Open Access
735 Views
23 Pages

Physicochemical, Sensorial and Calcium Bioavailability of Jelly Prepared Using Fish Gelatin in Combination with Furcellaran and Calcium L-Threonate

  • Tanyamon Petcharat,
  • Manat Chaijan,
  • Sylvia Indriani,
  • Supatra Karnjanapratum,
  • Nilesh Nirmal,
  • Jaspreet Singh,
  • Ihlana Nairfana and
  • Sitthipong Nalinanon

28 December 2025

Confectionery products, specifically jelly and gummy, require optimized structural, thermal, and nutritional properties for functionality and consumer acceptance. This study investigated the impact of furcellaran (FUR) and calcium L-threonate (Ca) on...

  • Article
  • Open Access
21 Citations
3,656 Views
23 Pages

Bioceramics Based on β-Calcium Pyrophosphate

  • Tatiana Safronova,
  • Andrey Kiselev,
  • Irina Selezneva,
  • Tatiana Shatalova,
  • Yulia Lukina,
  • Yaroslav Filippov,
  • Otabek Toshev,
  • Snezhana Tikhonova,
  • Olga Antonova and
  • Alexander Knotko

25 April 2022

Ceramic samples based on β-calcium pyrophosphate β-Ca2P2O7 were prepared from powders of γ-calcium pyrophosphate γ-Ca2P2O7 with preset molar ratios Ca/P = 1, 0.975 and 0.95 using firing at 900, 1000, and 1100 °C. Calcium lac...

  • Article
  • Open Access
14 Citations
3,528 Views
14 Pages

Extracellular Calcium-Induced Calcium Transient Regulating the Proliferation of Osteoblasts through Glycolysis Metabolism Pathways

  • Xiaohang Gao,
  • Xiaohui Di,
  • Jingjing Li,
  • Yiting Kang,
  • Wenjun Xie,
  • Lijun Sun and
  • Jianbao Zhang

During bone remodeling, high extracellular calcium levels accumulated around the resorbing bone tissue as soon as the activation of osteoclasts. However, if and how calcium is involved in the regulation of bone remodeling remains unclear. In this stu...

  • Article
  • Open Access
1 Citations
974 Views
19 Pages

26 June 2025

This work shows how the presence of calcium carbonate and sodium carbonate (5% and 20%) affects the hydration of a commercial calcium sulfoaluminate clinker (KCSA). For this study, water-hydrated pastes were prepared and the mechanical compressive st...

  • Article
  • Open Access
1,703 Views
18 Pages

6 September 2025

Peptide–calcium complexes exhibit promise as calcium supplements due to their enhanced bioavailability. Phosvitin nonapeptide DEEENDQVK (DK) possesses a high calcium-binding capability. This study investigated the calcium transport-promoting pr...

  • Article
  • Open Access
33 Citations
5,660 Views
13 Pages

6 June 2018

Hybrid composites with low flammability based on renewable calcium alginate and nano-calcium borate were fabricated using an in situ method through a simple, eco-friendly vacuum drying process. The composites were characterized by X-ray diffractometr...

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