Next Article in Journal
Unusual Foreign Object in a Tooth: A Case Report and Review of Literature
Previous Article in Journal
Multidisciplinary Approach to Bilaterally Missing Lateral Incisors: A Case Report
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Clinics and Practice
Volume 9
Issue 1
10.4081/cp.2019.1096
clinpract-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Isolated Hemopericardium after Initiation of Rivaroxaban: Implications and Potential Mechanisms

by
Adwait Mehta
1,
David Burkland
1,2 and
Nilesh Mathuria
1,*
1
Texas Heart Institute, Texas, USA
2
Baylor College of Medicine, Texas, USA
*
Author to whom correspondence should be addressed.
Clin. Pract. 2019, 9(1), 1096; https://doi.org/10.4081/cp.2019.1096
Submission received: 9 July 2018 / Revised: 11 January 2019 / Accepted: 17 January 2019 / Published: 30 January 2019

Abstract

Direct oral anticoagulants have become increasingly used for atrial fibrillation and venothromboembolic disease. Thus far, there have been a few published cases of pericardial effusion associated with rivaroxban. However, there has been little published regarding the effects of concurrent medications and their effect on the cytochrome enzyme systems involved in rivaroxaban metabolism. We present a case of a 76-year-old female who develops a spontaneous haemopericardium after initiating rivaroxaban. After thorough medical reconciliation, we offer pharmacokinetic mechanisms that may have contributed to the haemopericardium. This case demonstrates the importance of reviewing patients medication lists and utilizing basic pharmacokinetics to prevent adverse events.
Keywords: direct oral anticoagulants; rivaroxaban; pericardial effusion direct oral anticoagulants; rivaroxaban; pericardial effusion

Share and Cite

MDPI and ACS Style

Mehta, A.; Burkland, D.; Mathuria, N. Isolated Hemopericardium after Initiation of Rivaroxaban: Implications and Potential Mechanisms. Clin. Pract. 2019, 9, 1096. https://doi.org/10.4081/cp.2019.1096

AMA Style

Mehta A, Burkland D, Mathuria N. Isolated Hemopericardium after Initiation of Rivaroxaban: Implications and Potential Mechanisms. Clinics and Practice. 2019; 9(1):1096. https://doi.org/10.4081/cp.2019.1096

Chicago/Turabian Style

Mehta, Adwait, David Burkland, and Nilesh Mathuria. 2019. "Isolated Hemopericardium after Initiation of Rivaroxaban: Implications and Potential Mechanisms" Clinics and Practice 9, no. 1: 1096. https://doi.org/10.4081/cp.2019.1096

APA Style

Mehta, A., Burkland, D., & Mathuria, N. (2019). Isolated Hemopericardium after Initiation of Rivaroxaban: Implications and Potential Mechanisms. Clinics and Practice, 9(1), 1096. https://doi.org/10.4081/cp.2019.1096

Article Metrics

Back to TopTop