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Clinics and Practice
Volume 7
Issue 4
10.4081/cp.2017.982
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Clinics and Practice is published by MDPI from Volume 11 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Paraneoplastic Edematous Dermatomyositis: A Rare Syndrome Observed in a Case of Small Cell Lung Cancer

by
Kevin Zarrabi
1,*,
Terence Choy
1,
Keith Sweeney
2,
Ved Desai
1 and
Roger Keresztes
1
1
Department of Medicine, Stony Brook University Hospital, Stony Brook, NY, USA
2
Department of Pathology, Stony Brook University Hospital, Stony Brook, NY, USA
*
Author to whom correspondence should be addressed.
Clin. Pract. 2017, 7(4), 982; https://doi.org/10.4081/cp.2017.982
Submission received: 25 May 2017 / Revised: 25 May 2017 / Accepted: 12 October 2017 / Published: 23 October 2017

Abstract

Dermatomyositis with subcutaneous edema is a rare process with few reported cases. We report a 63-year-old with lung cancer who presented with an erythematous skin rash and was found to have biopsyproven dermatomyositis. Her course was complicated by generalized edema, myalgias, muscle weakness, dysphagia, and laryngeal edema. The edema was severe and caused respiratory distress requiring intubation. The patient underwent therapy with high-dose glucocorticoids and intravenous immunoglobulin but failed treatment. Altogether, she presented as an extreme case and rare variant of dermatomyositis, known as edematous dermatomyositis. Diagnostic and treatment guidelines do not account for this variant and literature pertaining to edematous dermatomyositis is sparse. Moreover, this disease was a paraneoplastic manifestation of her small cell lung cancer, which is rarely observed. There are no cases reporting edematous dermatomyositis as a paraneoplastic manifestation of small cell lung cancer, and we highlight the high rate of morbidity and mortality in such patients.
Keywords: edematous dermatomyositis; paraneoplastic; small cell lung cancer edematous dermatomyositis; paraneoplastic; small cell lung cancer

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MDPI and ACS Style

Zarrabi, K.; Choy, T.; Sweeney, K.; Desai, V.; Keresztes, R. Paraneoplastic Edematous Dermatomyositis: A Rare Syndrome Observed in a Case of Small Cell Lung Cancer. Clin. Pract. 2017, 7, 982. https://doi.org/10.4081/cp.2017.982

AMA Style

Zarrabi K, Choy T, Sweeney K, Desai V, Keresztes R. Paraneoplastic Edematous Dermatomyositis: A Rare Syndrome Observed in a Case of Small Cell Lung Cancer. Clinics and Practice. 2017; 7(4):982. https://doi.org/10.4081/cp.2017.982

Chicago/Turabian Style

Zarrabi, Kevin, Terence Choy, Keith Sweeney, Ved Desai, and Roger Keresztes. 2017. "Paraneoplastic Edematous Dermatomyositis: A Rare Syndrome Observed in a Case of Small Cell Lung Cancer" Clinics and Practice 7, no. 4: 982. https://doi.org/10.4081/cp.2017.982

APA Style

Zarrabi, K., Choy, T., Sweeney, K., Desai, V., & Keresztes, R. (2017). Paraneoplastic Edematous Dermatomyositis: A Rare Syndrome Observed in a Case of Small Cell Lung Cancer. Clinics and Practice, 7(4), 982. https://doi.org/10.4081/cp.2017.982

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