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Case Report

Oncocytic Pleomorphic Adenoma of Palatal Salivary Gland with Macrophages and Giant Cells Associated with Cholesterol Crystals

1
Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Maharashtra, India
2
Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Saudi Arabia
3
Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin Abdulaziz University, Saudi Arabia
*
Author to whom correspondence should be addressed.
Clin. Pract. 2016, 6(4), 884; https://doi.org/10.4081/cp.2016.884
Submission received: 23 August 2016 / Revised: 28 September 2016 / Accepted: 11 October 2016 / Published: 24 October 2016

Abstract

Pleomorphic adenoma (PA) is the most common salivary gland tumor characterized by histo-morphological diversity in the form of myxoid, hyalinized, chondroid, osseous, and squamous areas. In this paper, we report a rare case of predominantly oncocytic variant of PA in a 45-year-old male patient on the posterior palatal region. Microscopic examination showed homogenous eosinophilic cellular mass composed of epithelial components arranged in the form of tubular and solid patterns. The polygonal and oval cells showed abundant dark eosinophilic granular cytoplasm. The cell borders were distinct with a central nucleus showing prominent nucleoli. Interestingly at few places, cholesterol clefts were seen surrounded by macrophages and giant cells. The tumor was surgically excised with no evidence of recurrence after 2 years.
Keywords: salivary gland tumor; pleomorphic adenoma; oncocytes; cholesterol crystals salivary gland tumor; pleomorphic adenoma; oncocytes; cholesterol crystals

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MDPI and ACS Style

Sarode, G.S.; Sarode, S.C.; Patil, S.; Anil, S. Oncocytic Pleomorphic Adenoma of Palatal Salivary Gland with Macrophages and Giant Cells Associated with Cholesterol Crystals. Clin. Pract. 2016, 6, 884. https://doi.org/10.4081/cp.2016.884

AMA Style

Sarode GS, Sarode SC, Patil S, Anil S. Oncocytic Pleomorphic Adenoma of Palatal Salivary Gland with Macrophages and Giant Cells Associated with Cholesterol Crystals. Clinics and Practice. 2016; 6(4):884. https://doi.org/10.4081/cp.2016.884

Chicago/Turabian Style

Sarode, Gargi S., Sachin C. Sarode, Shankargouda Patil, and Sukumaran Anil. 2016. "Oncocytic Pleomorphic Adenoma of Palatal Salivary Gland with Macrophages and Giant Cells Associated with Cholesterol Crystals" Clinics and Practice 6, no. 4: 884. https://doi.org/10.4081/cp.2016.884

APA Style

Sarode, G. S., Sarode, S. C., Patil, S., & Anil, S. (2016). Oncocytic Pleomorphic Adenoma of Palatal Salivary Gland with Macrophages and Giant Cells Associated with Cholesterol Crystals. Clinics and Practice, 6(4), 884. https://doi.org/10.4081/cp.2016.884

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