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Case Report

Computed Tomography-Guided Cryoablation of Local Recurrence after Primary Resection of Pancreatic Adenocarcinoma

by
Claudio Pusceddu
1,
Luca Melis
1,
Barbara Sotgia
1,
Alessandro Fancellu
2,* and
Giovanni Battista Meloni
3
1
Division of Interventional Radiology, Department of Oncological Radiology, Oncological Hospital A. Businco, Cagliari, Italy
2
Unit of General Surgery 2, Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy
3
Institute of Radiological Sciences, University of Sassari, Sassari, Italy
*
Author to whom correspondence should be addressed.
Clin. Pract. 2015, 5(2), 741; https://doi.org/10.4081/cp.2015.741
Submission received: 8 December 2014 / Revised: 17 February 2015 / Accepted: 11 March 2015 / Published: 23 June 2015

Abstract

The optimal management of local recurrences after primary resection of pancreatic cancer still remains to be clarified. A 58-year old woman developed an isolated recurrence of pancreatic cancer six year after distal pancreatectomy. Re-resection was attempted but the lesion was deemed unresectable at surgery. Then chemotherapy was administrated without obtaining a reduction of the tumor size nor an improvement of the patient’s symptoms. Thus the patient underwent percutaneous cryoablation under computed tomography (CT)-guidance obtaining tumor necrosis and a significant improvement in the quality of life. A CT scan one month later showed a stable lesion with no contrast enhancement. While the use of percutaneous cryoblation has widened its applications in patients with unresectable pancreatic cancer, it has never been described for the treatment of local pancreatic cancer recurrence after primary resection. Percutaneous cryoablation deserves further studies in the multimodality treatment of local recurrence after primary pancreatic surgery.
Keywords: pancreatic cancer; recurrence; percutaneous cryoablation; computed tomography scan pancreatic cancer; recurrence; percutaneous cryoablation; computed tomography scan

Share and Cite

MDPI and ACS Style

Pusceddu, C.; Melis, L.; Sotgia, B.; Fancellu, A.; Meloni, G.B. Computed Tomography-Guided Cryoablation of Local Recurrence after Primary Resection of Pancreatic Adenocarcinoma. Clin. Pract. 2015, 5, 741. https://doi.org/10.4081/cp.2015.741

AMA Style

Pusceddu C, Melis L, Sotgia B, Fancellu A, Meloni GB. Computed Tomography-Guided Cryoablation of Local Recurrence after Primary Resection of Pancreatic Adenocarcinoma. Clinics and Practice. 2015; 5(2):741. https://doi.org/10.4081/cp.2015.741

Chicago/Turabian Style

Pusceddu, Claudio, Luca Melis, Barbara Sotgia, Alessandro Fancellu, and Giovanni Battista Meloni. 2015. "Computed Tomography-Guided Cryoablation of Local Recurrence after Primary Resection of Pancreatic Adenocarcinoma" Clinics and Practice 5, no. 2: 741. https://doi.org/10.4081/cp.2015.741

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