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Journal of Xenobiotics, Volume 11, Issue 2

June 2021 - 4 articles

Cover Story: Marine dinoflagellates from the genus Amphidinium produce a broad array of bioactive polyketides, some with toxicity that could disturb interactions in benthic trophic webs and potentially cause seafood poisoning. Hence, this study demonstrates the high bioactivity of a cultured strain of A. operculatum (AA60) from a coral reef system in the Gulf of Mexico against brine shrimp nauplii to evaluate microenvironmental toxin risk. However, scientific interest in these compounds goes beyond their hazardous environmental effects, given their high cell potency for biotechnological purposes. Cytotoxicity screening of the ethanolic crude extract of AA60 cells against six human cancer cell lines showed moderate to high growth inhibition, which is effective in breast and lung cancer cell lines MCF-7 and SKLU-1. View this paper

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Review

12 Citations

7,692 Views

17 Pages

Pathogenesis and Management of COVID-19

Khalid O. Alfarouk,
Sari T. S. AlHoufie,
Samrein B. M. Ahmed,
Mona Shabana,
Ahmed Ahmed,
Saad S. Alqahtani,
Ali S. Alqahtani,
Ali M. Alqahtani,
AbdelRahman M. Ramadan and
Mohamed E. Ahmed
+ 7 authors

J. Xenobiot.2021, 11(2), 77-93;https://doi.org/10.3390/jox11020006

21 May 2021

COVID-19, occurring due to SARS-COV-2 infection, is the most recent pandemic disease that has led to three million deaths at the time of writing. A great deal of effort has been directed towards altering the virus trajectory and/or managing the inter...

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Review

66 Citations

12,522 Views

16 Pages

Pharmaceutical Pollution and Disposal of Expired, Unused, and Unwanted Medicines in the Brazilian Context

Letícia de Araújo Almeida Freitas and
Gandhi Radis-Baptista

J. Xenobiot.2021, 11(2), 61-76;https://doi.org/10.3390/jox11020005

18 May 2021

The occurrence of pharmaceuticals in the environment is an everyday recognized concern worldwide, and drugs as environmental contaminants have been detected in water and soil systems, posing risks to humans and wildlife. The presence of drugs in wast...

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Article

10 Citations

4,262 Views

15 Pages

Changes of Heart Rate and Lipid Composition in Mytilus Edulis and Modiolus Modiolus Caused by Crude Oil Pollution and Low Salinity Effects

Igor Bakhmet,
Natalia Fokina and
Tatiana Ruokolainen

J. Xenobiot.2021, 11(2), 46-60;https://doi.org/10.3390/jox11020004

14 May 2021

Blue mussels, Mytilus edulis, inhabiting tidal zones, are naturally exposed to fluctuating environmental conditions (e.g., fluctuations in temperature and salinities), while horse mussels, Modiolus modiolus, live under relatively invariable shelf wat...

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Article

10 Citations

6,813 Views

13 Pages

Toxicity Bioassay and Cytotoxic Effects of the Benthic Marine Dinoflagellate Amphidinium operculatum

Ana Luisa Mejía-Camacho,
Lorena María Durán-Riveroll and
Allan Douglas Cembella

J. Xenobiot.2021, 11(2), 33-45;https://doi.org/10.3390/jox11020003

27 April 2021

Benthic dinoflagellates produce a wide array of bioactive compounds, primarily polyketides, that cause toxic effects on human consumers of seafood and perhaps mediate species interactions in the benthic microenvironment. This study assesses toxic and...

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J. Xenobiot. - ISSN 2039-4713

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