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Review

Overview of Chelation Recommendations for Thalassaemia and Sickle Cell Disease

Barts Health NHS Trust, Royal London Hospital, London, UK
Thalass. Rep. 2014, 4(3), 4860; https://doi.org/10.4081/thal.2014.4860
Submission received: 25 September 2014 / Revised: 5 November 2014 / Accepted: 1 December 2014 / Published: 4 December 2014

Abstract

The long term consequences of iron toxicity are mostly reversible with effective iron chelation therapy. Recommendations for use of chelation therapy in transfusion dependent thalassaemia (TDT), sickle cell disease (SCD) and non transfusion dependent thalassaemia (NTDT) continue to evolve as our knowledge and clinical experience increases. Improved chelation options including drug combinations and a better understanding of condition specific factors may help to improve efficiency of chelation regimens and meet the needs of patients more effectively.
Keywords: iron toxicity; thalassaemia; sickle cell disease; chelation therapy; drug iron toxicity; thalassaemia; sickle cell disease; chelation therapy; drug

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MDPI and ACS Style

Kaya, B. Overview of Chelation Recommendations for Thalassaemia and Sickle Cell Disease. Thalass. Rep. 2014, 4, 4860. https://doi.org/10.4081/thal.2014.4860

AMA Style

Kaya B. Overview of Chelation Recommendations for Thalassaemia and Sickle Cell Disease. Thalassemia Reports. 2014; 4(3):4860. https://doi.org/10.4081/thal.2014.4860

Chicago/Turabian Style

Kaya, Banu. 2014. "Overview of Chelation Recommendations for Thalassaemia and Sickle Cell Disease" Thalassemia Reports 4, no. 3: 4860. https://doi.org/10.4081/thal.2014.4860

APA Style

Kaya, B. (2014). Overview of Chelation Recommendations for Thalassaemia and Sickle Cell Disease. Thalassemia Reports, 4(3), 4860. https://doi.org/10.4081/thal.2014.4860

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