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Volume 7
Issue 4
10.4081/pr.2015.6338
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Case Report

Neonatal Hemophilia: A Rare Presentation

by
Nuno Ferreira
1,*,
Elisa Proença
1,
Cristina Godinho
1,
Dulce Oliveira
1,
Ana Guedes
1,
Sara Morais
2 and
Carmen Carvalho
1
1
Neonatal Intensive Care Unit, Portugal
2
Clinical Hematology Department, Centro Hospitalar do Porto, Portugal
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2015, 7(4), 6338; https://doi.org/10.4081/pr.2015.6338
Submission received: 30 November 2015 / Accepted: 17 December 2015 / Published: 21 December 2015

Abstract

Hemophilia A is a X-linked hereditary condition that lead to decreased factor VIII activity, occurs mainly in males. Decreased factor VIII activity leads to increased risk of bleeding events. During neonatal period, diagnosis is made after post-partum bleeding complication or unexpected bleeding after medical procedures. Subgaleal hemorrhage during neonatal period is a rare, severe extracranial bleeding with high mortality and usually related to traumatic labor or coagulation disorders. Subgaleal hemorrhage complications result from massive bleeding. We present a neonate with unremarkable family history and uneventful pregnancy with a vaginal delivery with no instrumentation, presenting with severe subgaleal bleeding at 52 hours of life. Aggressive support measures were implemented and bleeding managed. The unexpected bleeding lead to a coagulation study and the diagnosis of severe hemophilia A. There were no known sequelae. This case shows a rare hemophilia presentation reflecting the importance of coagulation studies when faced with unexplained severe bleeding.
Keywords: Hemophilia A; subgaleal hemorrhage; neonate; extracranial bleeding Hemophilia A; subgaleal hemorrhage; neonate; extracranial bleeding

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MDPI and ACS Style

Ferreira, N.; Proença, E.; Godinho, C.; Oliveira, D.; Guedes, A.; Morais, S.; Carvalho, C. Neonatal Hemophilia: A Rare Presentation. Pediatr. Rep. 2015, 7, 6338. https://doi.org/10.4081/pr.2015.6338

AMA Style

Ferreira N, Proença E, Godinho C, Oliveira D, Guedes A, Morais S, Carvalho C. Neonatal Hemophilia: A Rare Presentation. Pediatric Reports. 2015; 7(4):6338. https://doi.org/10.4081/pr.2015.6338

Chicago/Turabian Style

Ferreira, Nuno, Elisa Proença, Cristina Godinho, Dulce Oliveira, Ana Guedes, Sara Morais, and Carmen Carvalho. 2015. "Neonatal Hemophilia: A Rare Presentation" Pediatric Reports 7, no. 4: 6338. https://doi.org/10.4081/pr.2015.6338

APA Style

Ferreira, N., Proença, E., Godinho, C., Oliveira, D., Guedes, A., Morais, S., & Carvalho, C. (2015). Neonatal Hemophilia: A Rare Presentation. Pediatric Reports, 7(4), 6338. https://doi.org/10.4081/pr.2015.6338

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