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Pediatric Reports
Volume 6
Issue 3
10.4081/pr.2014.5447
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Pediatric Reports is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Virilizing Ovarian Fibrothecoma with Minor Sex Cord Elements in a 13 Year Old Girl: A Rare Case

by
Neelam Sood
1,
Jitendra Singh Nigam
2,*,
Geetika Goyal
1 and
Reeta Ranjan
1
1
Department of Pathology, Deen Dayal Upadhyay Hospital, Hari Nagar, New Delhi
2
Department of Pathology, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur, UP
3
Department of Obstetric And Gynecology, Deen Dayal Upadhyay Hospital, Hari Nagar, New Delhi, India
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2014, 6(3), 5447; https://doi.org/10.4081/pr.2014.5447
Submission received: 17 April 2014 / Revised: 17 April 2014 / Accepted: 23 July 2014 / Published: 12 August 2014

Abstract

Fibrothecoma accounts for 3-4% of all ovarian neoplasms; it is usually hormonally inactive, but can be estrogenic or sometimes androgenic (11%); it is rare under 30 years. In a very few cases, minor sex cord elements (less than 10% of the tumor area) are present; therefore, it is considered as a separate sub-group of stromal tumors. The importance of immunohistochemistry in recognizing this kind of tumor has been fully documented, with variable results on inhibin staining, but specific positivity for calretenin in such cases. We report here the rare case of a 13-year-old child with ovarian fibrothecoma and minor sex cord stromal elements, who showed negativity for inhibin and positivity for calretenin.
Keywords: estrogenic; immunohistochemistry; inhibin; calretenin estrogenic; immunohistochemistry; inhibin; calretenin

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MDPI and ACS Style

Sood, N.; Nigam, J.S.; Goyal, G.; Ranjan, R. Virilizing Ovarian Fibrothecoma with Minor Sex Cord Elements in a 13 Year Old Girl: A Rare Case. Pediatr. Rep. 2014, 6, 5447. https://doi.org/10.4081/pr.2014.5447

AMA Style

Sood N, Nigam JS, Goyal G, Ranjan R. Virilizing Ovarian Fibrothecoma with Minor Sex Cord Elements in a 13 Year Old Girl: A Rare Case. Pediatric Reports. 2014; 6(3):5447. https://doi.org/10.4081/pr.2014.5447

Chicago/Turabian Style

Sood, Neelam, Jitendra Singh Nigam, Geetika Goyal, and Reeta Ranjan. 2014. "Virilizing Ovarian Fibrothecoma with Minor Sex Cord Elements in a 13 Year Old Girl: A Rare Case" Pediatric Reports 6, no. 3: 5447. https://doi.org/10.4081/pr.2014.5447

APA Style

Sood, N., Nigam, J. S., Goyal, G., & Ranjan, R. (2014). Virilizing Ovarian Fibrothecoma with Minor Sex Cord Elements in a 13 Year Old Girl: A Rare Case. Pediatric Reports, 6(3), 5447. https://doi.org/10.4081/pr.2014.5447

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