Next Article in Journal
Nanoparticle-Laden Contact Lens for Controlled Ocular Delivery of Prednisolone: Formulation Optimization Using Statistical Experimental Design
Next Article in Special Issue
Nanomilling of Drugs for Bioavailability Enhancement: A Holistic Formulation-Process Perspective
Previous Article in Journal
Timing of Administration: For Commonly-Prescribed Medicines in Australia
Article Menu

Export Article

Open AccessFeature PaperCommunication
Pharmaceutics 2016, 8(2), 11;

Turning Waste into Value: Nanosized Natural Plant Materials of Solanum incanum L. and Pterocarpus erinaceus Poir with Promising Antimicrobial Activities

Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, Saarbruecken D-66123, Germany
Department of Biotechnology, University of Applied Sciences, Kaiserslautern, Zweibruecken 66482, Germany
Laboratoire de Botanique et Ecologie Végétale, Université de Lomé, BP 1515 Lomé, Togo
CNRS (Centre National de la Recherche Scientifique), SRSMC (Structure et Réactivité des Systèmes Moléculaires Complexes) UMR 7565, 1 boulevard Arago, Metz F57070, France
Université de Lorraine, SRSMC, UMR 7565, Nancy Cedex F-54001, France
Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University-Medical College, ul. Medyczna 9, Cracow 30-688, Poland
ABC Platform, Faculté de Pharmacie, Nancy Cedex F-54001, France
Department of Pharmacognosy, Faculty of Clinical Pharmacy, Al Baha University, Al Baha 15791, Saudi Arabia
Institute of Pharmaceutics and Biopharmaceutics, Philipps-Universität Marburg, Marburg 35032, Germany
Authors to whom correspondence should be addressed.
Academic Editor: Leena Peltonen
Received: 2 February 2016 / Revised: 20 March 2016 / Accepted: 23 March 2016 / Published: 19 April 2016
(This article belongs to the Special Issue Nanocrystals)
Full-Text   |   PDF [7354 KB, uploaded 19 April 2016]   |  


Numerous plants are known to exhibit considerable biological activities in the fields of medicine and agriculture, yet access to their active ingredients is often complicated, cumbersome and expensive. As a consequence, many plants harbouring potential drugs or green phyto-protectants go largely unnoticed, especially in poorer countries which, at the same time, are in desperate need of antimicrobial agents. As in the case of plants such as the Jericho tomato, Solanum incanum, and the common African tree Pterocarpus erinaceus, nanosizing of original plant materials may provide an interesting alternative to extensive extraction and isolation procedures. Indeed, it is straightforward to obtain considerable amounts of such common, often weed-like plants, and to mill the dried material to more or less uniform particles of microscopic and nanoscopic size. These particles exhibit activity against Steinernema feltiae or Escherichia coli, which is comparable to the ones seen for processed extracts of the same, respective plants. As S. feltiae is used as a model nematode indicative of possible phyto-protective uses in the agricultural arena, these findings also showcase the potential of nanosizing of crude “waste” plant materials for specific practical applications, especially—but not exclusively—in developing countries lacking a more sophisticated industrial infrastructure. View Full-Text
Keywords: nanosizing; antimicrobial activity; phyto-protectant; Pterocarpus erinaceus; Solanum incanum nanosizing; antimicrobial activity; phyto-protectant; Pterocarpus erinaceus; Solanum incanum

Figure 1a

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Griffin, S.; Tittikpina, N.K.; Al-marby, A.; Alkhayer, R.; Denezhkin, P.; Witek, K.; Gbogbo, K.A.; Batawila, K.; Duval, R.E.; Nasim, M.J.; Awadh-Ali, N.A.; Kirsch, G.; Chaimbault, P.; Schäfer, K.-H.; Keck, C.M.; Handzlik, J.; Jacob, C. Turning Waste into Value: Nanosized Natural Plant Materials of Solanum incanum L. and Pterocarpus erinaceus Poir with Promising Antimicrobial Activities. Pharmaceutics 2016, 8, 11.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Pharmaceutics EISSN 1999-4923 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top