Hepatitis C Virus P7—A Viroporin Crucial for Virus Assembly and an Emerging Target for Antiviral Therapy
Abstract
:1. Introduction
2. Structure and Function of HCV P7
2.1. P7 Topology and Structure
2.2. P7—A Viroporin and True Ion Channel?
2.3. Subcellular Localization of P7
2.4. Clues of P7 Function Based on Animal and Tissue Culture Experiments
3. P7-Based Antiviral Strategies
3.1. Amantadine
3.2. Amilorides
3.3. Iminosugar Derivatives
3.4. BIT225
4. Conclusion and Outlook
Acknowledgements
References and Notes
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Steinmann, E.; Pietschmann, T. Hepatitis C Virus P7—A Viroporin Crucial for Virus Assembly and an Emerging Target for Antiviral Therapy. Viruses 2010, 2, 2078-2095. https://doi.org/10.3390/v2092078
Steinmann E, Pietschmann T. Hepatitis C Virus P7—A Viroporin Crucial for Virus Assembly and an Emerging Target for Antiviral Therapy. Viruses. 2010; 2(9):2078-2095. https://doi.org/10.3390/v2092078
Chicago/Turabian StyleSteinmann, Eike, and Thomas Pietschmann. 2010. "Hepatitis C Virus P7—A Viroporin Crucial for Virus Assembly and an Emerging Target for Antiviral Therapy" Viruses 2, no. 9: 2078-2095. https://doi.org/10.3390/v2092078
APA StyleSteinmann, E., & Pietschmann, T. (2010). Hepatitis C Virus P7—A Viroporin Crucial for Virus Assembly and an Emerging Target for Antiviral Therapy. Viruses, 2(9), 2078-2095. https://doi.org/10.3390/v2092078