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Open AccessFeature PaperArticle

Nanoscale Topographical Characterization of Orbital Implant Materials

Materials Characterization Facility, Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163 Genova, Italy
Department of Chemistry and Industrial Chemistry, Università di Genova, Via Dodecaneso 31, 16146 Genova, Italy
Institute of Materials Physics and Engineering, Applied Science and Technology Department, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy
Author to whom correspondence should be addressed.
Materials 2018, 11(5), 660;
Received: 31 March 2018 / Revised: 14 April 2018 / Accepted: 23 April 2018 / Published: 24 April 2018
(This article belongs to the Special Issue State-of-the-Art Materials Science in Italy 2017)
The search for an ideal orbital implant is still ongoing in the field of ocular biomaterials. Major limitations of currently-available porous implants include the high cost along with a non-negligible risk of exposure and postoperative infection due to conjunctival abrasion. In the effort to develop better alternatives to the existing devices, two types of new glass-ceramic porous implants were fabricated by sponge replication, which is a relatively inexpensive method. Then, they were characterized by direct three-dimensional (3D) contact probe mapping in real space by means of atomic force microscopy in order to assess their surface micro- and nano-features, which were quantitatively compared to those of the most commonly-used orbital implants. These silicate glass-ceramic materials exhibit a surface roughness in the range of a few hundred nanometers (Sq within 500–700 nm) and topographical features comparable to those of clinically-used “gold-standard” alumina and polyethylene porous orbital implants. However, it was noted that both experimental and commercial non-porous implants were significantly smoother than all the porous ones. The results achieved in this work reveal that these porous glass-ceramic materials show promise for the intended application and encourage further investigation of their clinical suitability. View Full-Text
Keywords: bioceramic; glass-ceramic; orbital implant; roughness; atomic force microscopy; ocular surgery; enucleation bioceramic; glass-ceramic; orbital implant; roughness; atomic force microscopy; ocular surgery; enucleation
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MDPI and ACS Style

Salerno, M.; Reverberi, A.P.; Baino, F. Nanoscale Topographical Characterization of Orbital Implant Materials. Materials 2018, 11, 660.

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