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Volume 2, March

Materials, Volume 1, Issue 1 (December 2008) – 3 articles , Pages 1-43

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Article
Modulating the Release Kinetics of Paclitaxel from Membrane-Covered Stents Using Different Loading Strategies
Materials 2008, 1(1), 25-43; https://doi.org/10.3390/ma1010025 - 07 Nov 2008
Cited by 6 | Viewed by 10159
Abstract
Membrane-covered Express2TM Monorail® stents composed of chitosan (CH) blended with polyethylene oxide (PEO) in 70:30% wt (CH-PEO) were coated with a monolayer of hyaluronic acid (HA). This significantly improved the resistance to platelet adhesion and demonstrated excellent mechanical properties, resisting the [...] Read more.
Membrane-covered Express2TM Monorail® stents composed of chitosan (CH) blended with polyethylene oxide (PEO) in 70:30% wt (CH-PEO) were coated with a monolayer of hyaluronic acid (HA). This significantly improved the resistance to platelet adhesion and demonstrated excellent mechanical properties, resisting the harsh conditions during stent crimping and subsequent inflation. CH-PEO/HA membrane was then combined with a paclitaxel (Pac) delivery system via three different approaches for comparison of release profiles of Pac. The activity of Pac in these systems was confirmed since its presence in the membrane significantly decreased cell viability of U937 macrophages. Presented results are promising for applications requiring different release patterns of hydrophobic drugs. Full article
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Article
Lessons from a “Failed” Experiment: Zinc Silicates with Complex Morphology by Reaction of Zinc Acetate, the Ionic Liquid Precursor (ILP) Tetrabutylammonium Hydroxide (TBAH), and Glass
Materials 2008, 1(1), 3-24; https://doi.org/10.3390/ma1010003 - 29 Aug 2008
Cited by 36 | Viewed by 11168
Abstract
At elevated temperatures, the ionic liquid precursor (ILP) tetrabutylammonium hydroxide reacts with zinc acetate and the glass wall of the reaction vessel. While the reaction of OH- with the glass wall is not surprising as such and could be considered a failed [...] Read more.
At elevated temperatures, the ionic liquid precursor (ILP) tetrabutylammonium hydroxide reacts with zinc acetate and the glass wall of the reaction vessel. While the reaction of OH- with the glass wall is not surprising as such and could be considered a failed experiment, the resulting materials are interesting for a variety of applications. If done on purpose and under controlled conditions, the reaction with the glass wall results in uniform, well-defined hemimorphite Zn4Si2O7(OH)2·nH2O and willemite Zn2SiO4 microcrystals and films. Their morphology can be adjusted by variation of the reaction time and reaction temperature. The hemimorphite can be transformed to Zn2SiO4 via calcination. The process is therefore a viable approach for the fabrication of porous films on glass surfaces with potential applications as catalyst support, among others. Full article
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Editorial
Welcome to Materials – a New Open Access Journal for a Growing Scientific Community
Materials 2008, 1(1), 1-2; https://doi.org/10.3390/ma1010001 - 29 Aug 2008
Viewed by 7907
Abstract
Materials science is one of the key disciplines in modern society because only materials-oriented scientists can provide the necessary tools, building blocks, components, and processes that are needed for an ever growing and aging society.[...] Full article
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