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Case Report

Perianal Paget disease treated definitively with radiotherapy

Department of Radiation Oncology, New York Methodist Hospital, Weill Cornell Medical College, Brooklyn, NY, USA
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2012, 19(6), 496-500; https://doi.org/10.3747/co.19.1144
Submission received: 9 September 2012 / Revised: 2 October 2012 / Accepted: 6 November 2012 / Published: 1 December 2012

Abstract

Extramammary Paget disease (EMPD) is a relatively rare cutaneous disorder described as an apocrine gland tumour occurring in both a benign and a malignant form with metastatic potential. The areas of the body affected are the vulva, perianal region, penis, scrotum, perineum, and axilla, all of which contain apocrine glands. When EMPD affects the perianal region, it is called perianal Paget disease (PPD). All forms of EMPD, including PPD, are typically treated by wide surgical excision. Perianal Paget disease usually occurs later in life in patients who are often poor surgical candidates, but the available literature is scarce regarding other treatment modalities, including definitive radiotherapy. We contend that PPD can be safely and effectively treated with radiotherapy, and here, we present the case of a 75-year-old woman with PPD who was successfully so treated. A brief review of the literature concerning the diagnosis, natural history, and treatment of PPD is also included.
Keywords: Perianal Paget disease; extramammary Paget disease; radiotherapy Perianal Paget disease; extramammary Paget disease; radiotherapy

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MDPI and ACS Style

Mann, J.; Lavaf, A.; Tejwani, A.; Ross, P.; Ashamalla, H. Perianal Paget disease treated definitively with radiotherapy. Curr. Oncol. 2012, 19, 496-500. https://doi.org/10.3747/co.19.1144

AMA Style

Mann J, Lavaf A, Tejwani A, Ross P, Ashamalla H. Perianal Paget disease treated definitively with radiotherapy. Current Oncology. 2012; 19(6):496-500. https://doi.org/10.3747/co.19.1144

Chicago/Turabian Style

Mann, J., A. Lavaf, A. Tejwani, P. Ross, and H. Ashamalla. 2012. "Perianal Paget disease treated definitively with radiotherapy" Current Oncology 19, no. 6: 496-500. https://doi.org/10.3747/co.19.1144

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