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Current Oncology
Volume 19
Issue 6
10.3747/co.19.1144
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Background:
Case Report

Perianal Paget disease treated definitively with radiotherapy

by
J. Mann
*,
A. Lavaf
,
A. Tejwani
,
P. Ross
and
H. Ashamalla
Department of Radiation Oncology, New York Methodist Hospital, Weill Cornell Medical College, Brooklyn, NY, USA
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2012, 19(6), 496-500; https://doi.org/10.3747/co.19.1144
Submission received: 9 September 2012 / Revised: 2 October 2012 / Accepted: 6 November 2012 / Published: 1 December 2012

Abstract

Extramammary Paget disease (EMPD) is a relatively rare cutaneous disorder described as an apocrine gland tumour occurring in both a benign and a malignant form with metastatic potential. The areas of the body affected are the vulva, perianal region, penis, scrotum, perineum, and axilla, all of which contain apocrine glands. When EMPD affects the perianal region, it is called perianal Paget disease (PPD). All forms of EMPD, including PPD, are typically treated by wide surgical excision. Perianal Paget disease usually occurs later in life in patients who are often poor surgical candidates, but the available literature is scarce regarding other treatment modalities, including definitive radiotherapy. We contend that PPD can be safely and effectively treated with radiotherapy, and here, we present the case of a 75-year-old woman with PPD who was successfully so treated. A brief review of the literature concerning the diagnosis, natural history, and treatment of PPD is also included.
Keywords: Perianal Paget disease; extramammary Paget disease; radiotherapy Perianal Paget disease; extramammary Paget disease; radiotherapy

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MDPI and ACS Style

Mann, J.; Lavaf, A.; Tejwani, A.; Ross, P.; Ashamalla, H. Perianal Paget disease treated definitively with radiotherapy. Curr. Oncol. 2012, 19, 496-500. https://doi.org/10.3747/co.19.1144

AMA Style

Mann J, Lavaf A, Tejwani A, Ross P, Ashamalla H. Perianal Paget disease treated definitively with radiotherapy. Current Oncology. 2012; 19(6):496-500. https://doi.org/10.3747/co.19.1144

Chicago/Turabian Style

Mann, J., A. Lavaf, A. Tejwani, P. Ross, and H. Ashamalla. 2012. "Perianal Paget disease treated definitively with radiotherapy" Current Oncology 19, no. 6: 496-500. https://doi.org/10.3747/co.19.1144

APA Style

Mann, J., Lavaf, A., Tejwani, A., Ross, P., & Ashamalla, H. (2012). Perianal Paget disease treated definitively with radiotherapy. Current Oncology, 19(6), 496-500. https://doi.org/10.3747/co.19.1144

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