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Current Oncology
Volume 14
Issue 5
10.3747/co.2007.144
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Article

Cancer Antigen 125 in Ovarian Cancer Surveillance: A Decision Analysis Model

by
M. Laura Hopkins
1,*,
D. Coyle
2,
T. Le
1,
M. Fung Kee Fung
1 and
G. Wells
2
1
Division of Gynecologic Oncology, University of Ottawa, Ottawa, ON, Canada
2
Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, ON, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2007, 14(5), 167-172; https://doi.org/10.3747/co.2007.144
Submission received: 5 July 2007 / Revised: 5 August 2007 / Accepted: 5 September 2007 / Published: 1 October 2007

Abstract

We used decision analysis techniques with Markov cohort modeling to examine the role of cancer antigen 125 (CA-125) in follow-up surveillance strategies among patients with advanced ovarian cancer. Utilities were derived from a societal perspective. Using quality-adjusted life years (QALYs) as the outcome variable, the value of CA-125 monitoring for asymptomatic women with ovarian cancer was found to be reduced as compared with a strategy that includes CA-125 testing. Decisions to include CA-125 in surveillance strategies for ovarian cancer patients should be made after discussion with full disclosure of the preference-sensitive nature of CA-125. The model demonstrates that preferences and perspective can influence decisions in cancer care.
Keywords: decision analysis; CA-125; preferences decision analysis; CA-125; preferences

Share and Cite

MDPI and ACS Style

Hopkins, M.L.; Coyle, D.; Le, T.; Fung, M.F.K.; Wells, G. Cancer Antigen 125 in Ovarian Cancer Surveillance: A Decision Analysis Model. Curr. Oncol. 2007, 14, 167-172. https://doi.org/10.3747/co.2007.144

AMA Style

Hopkins ML, Coyle D, Le T, Fung MFK, Wells G. Cancer Antigen 125 in Ovarian Cancer Surveillance: A Decision Analysis Model. Current Oncology. 2007; 14(5):167-172. https://doi.org/10.3747/co.2007.144

Chicago/Turabian Style

Hopkins, M. Laura, D. Coyle, T. Le, M. Fung Kee Fung, and G. Wells. 2007. "Cancer Antigen 125 in Ovarian Cancer Surveillance: A Decision Analysis Model" Current Oncology 14, no. 5: 167-172. https://doi.org/10.3747/co.2007.144

APA Style

Hopkins, M. L., Coyle, D., Le, T., Fung, M. F. K., & Wells, G. (2007). Cancer Antigen 125 in Ovarian Cancer Surveillance: A Decision Analysis Model. Current Oncology, 14(5), 167-172. https://doi.org/10.3747/co.2007.144

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