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Nutraceuticals, Volume 2, Issue 1 (March 2022) – 3 articles

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17 pages, 1205 KiB  
Review
Goji Berry: Health Promoting Properties
by Prodromos Skenderidis, Stefanos Leontopoulos and Dimitrios Lampakis
Nutraceuticals 2022, 2(1), 32-48; https://doi.org/10.3390/nutraceuticals2010003 - 14 Mar 2022
Cited by 9 | Viewed by 8455
Abstract
Since ancient times, it has been noticed that Goji berry fruit juice, roots and leaves consist of ingredients that contain a wide variety of bioactive substances. The consumption of goji berry fruits results in properties which improve the subjective feeling of general well-being. [...] Read more.
Since ancient times, it has been noticed that Goji berry fruit juice, roots and leaves consist of ingredients that contain a wide variety of bioactive substances. The consumption of goji berry fruits results in properties which improve the subjective feeling of general well-being. The aim of this work is to present the information from the existing literature on the possible role of goji berry plant parts and their extracts as a functional food. Lycium barbarum Polysaccharides (LBP) and polyphenols are the most researched aspects of fruits associated with the promotion of human health. Goji berry fruits demonstrated anti-oxidative properties that are associated with age-related diseases such as diabetes, atherosclerosis and antitumor and immunoregulatory activities. Bioactive secondary metabolites contained in fruit lead to positive effects for human vision, while other biochemicals contained in the root bark have shown hepatoprotective and inhibitory actions on the rennin/angiotensin system. The results presented so far in the literature verify their use in traditional medicine. Full article
(This article belongs to the Special Issue Functional Foods as a New Therapeutic Strategy)
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10 pages, 1600 KiB  
Article
Anti-Inflammatory and Neuroprotective Effect of the Anti-Obesity Dietary Supplement Dekosilhue® in an In Vitro Model of Neuroinflammation
by Vittoria Borgonetti, Lorenzo Cenci and Nicoletta Galeotti
Nutraceuticals 2022, 2(1), 22-31; https://doi.org/10.3390/nutraceuticals2010002 - 8 Feb 2022
Cited by 1 | Viewed by 2841
Abstract
Obesity is now recognized as a global health problem and has reached epidemic proportions, affecting both developed and developing countries. This condition is associated with an increased incidence in central nervous system (CNS) disorders. The intake of foods or supplements with anti-inflammatory activity [...] Read more.
Obesity is now recognized as a global health problem and has reached epidemic proportions, affecting both developed and developing countries. This condition is associated with an increased incidence in central nervous system (CNS) disorders. The intake of foods or supplements with anti-inflammatory activity could potentially lead to a lower impact of obesity on the functionality of CNS. Therefore, in this work we tested the effect of a dietary supplement, DEKOSILHUE® (DSK), containing polyphenols enriched herbal extracts and successfully used for improving the control of body weight, in an in vitro inflammatory model. LPS-stimulated immortalized microglia BV2 cells have been used as a model of neuroinflammation. The stimulation with LPS increased the release and activation of several neuroinflammatory mediators, such as IKB⍺, HDAC-1, and IL-1ß. DSK reduced the levels and the activation of all these pro-inflammatory markers. In addition, DSK increased the expression of the anti-inflammatory cytokine IL-10, promoting an anti-inflammatory response. Finally, we showed that the anti-inflammatory effect of DSK can prevent the neurotoxicity related to microglia hyperactivation. In conclusion, DSK could potentially help in controlling neuroinflammation CNS, reducing microglia pro-inflammatory activation. Full article
(This article belongs to the Special Issue Current State of the Art—Nutraceutical Components of Foods)
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21 pages, 2934 KiB  
Article
Formulation of Rosemary Extracts through Spray-Drying Encapsulation or Emulsification
by Lamprini-Danai Kanakidi, Dimitrios Tsimogiannis, Sotirios Kiokias and Vassiliki Oreopoulou
Nutraceuticals 2022, 2(1), 1-21; https://doi.org/10.3390/nutraceuticals2010001 - 20 Jan 2022
Cited by 9 | Viewed by 4160
Abstract
Natural, plant-derived antioxidants can be used to prolong the shelf life of food or cosmetics, or as health-promoting additives. Although their extraction from plants has been extensively studied, purification and formulation processes need further research to allow their exploitation. In the present work, [...] Read more.
Natural, plant-derived antioxidants can be used to prolong the shelf life of food or cosmetics, or as health-promoting additives. Although their extraction from plants has been extensively studied, purification and formulation processes need further research to allow their exploitation. In the present work, rosemary extracts were obtained by successive extractions with acetone and water or single extraction by either an acetone:water or ethanol:water mixture. The extracts were analyzed by HPLC-DAD, and rosmarinic acid, carnosic acid, carnosol, and several flavonoids were identified and quantified. The extracts obtained by water or aqueous mixtures of organic solvents were encapsulated in maltodextrin combined with gum arabic with a high encapsulation yield (90–100%) and efficiency (97%) for rosmarinic acid and flavonoids. The acetone extract, rich in carnosic acid, was transformed to oil solution and either encapsulated or formulated in emulsion. The shelf life of encapsulated products was tested over a period of six months, and the results showed high retention of rosmarinic acid (88%) and lower of flavonoids (54–80%). Carnosic acid presented lower retention either encapsulated in solid powder (65–70% after one month at ambient temperature) or in emulsion (48% after 20 days of storage at 15 °C), while it was partially transformed to carnosol. Full article
(This article belongs to the Special Issue Current State of the Art—Nutraceutical Components of Foods)
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