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Sex- and Gender-Based Analysis in Cannabis Treatment Outcomes: A Systematic Review

1
Centre of Excellence for Women´s Health, E311-4500 Oak Street, Vancouver, BC V6H 3N1, Canada
2
School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(3), 872; https://doi.org/10.3390/ijerph17030872
Received: 31 December 2019 / Revised: 27 January 2020 / Accepted: 28 January 2020 / Published: 30 January 2020
(This article belongs to the Special Issue Sex, Gender and Substance Use)
There is evidence that sex- and gender-related factors are involved in cannabis patterns of use, health effects and biological mechanisms. Women and men report different cannabis use disorder (CUD) symptoms, with women reporting worse withdrawal symptoms than men. The objective of this systematic review was to examine the effectiveness of cannabis pharmacological interventions for women and men and the uptake of sex- and gender-based analysis in the included studies. Two reviewers performed the full-paper screening, and data was extracted by one researcher. The search yielded 6098 unique records—of which, 68 were full-paper screened. Four articles met the eligibility criteria for inclusion. From the randomized clinical studies of pharmacological interventions, few studies report sex-disaggregated outcomes for women and men. Despite emergent evidence showing the influence of sex and gender factors in cannabis research, sex-disaggregated outcomes in pharmacological interventions is lacking. Sex- and gender-based analysis is incipient in the included articles. Future research should explore more comprehensive inclusion of sex- and gender-related aspects in pharmacological treatments for CUD. View Full-Text
Keywords: sex- and gender-based analysis; SGBA; cannabis use disorder; randomized controlled trial sex- and gender-based analysis; SGBA; cannabis use disorder; randomized controlled trial
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MDPI and ACS Style

Brabete, A.C.; Greaves, L.; Hemsing, N.; Stinson, J. Sex- and Gender-Based Analysis in Cannabis Treatment Outcomes: A Systematic Review. Int. J. Environ. Res. Public Health 2020, 17, 872. https://doi.org/10.3390/ijerph17030872

AMA Style

Brabete AC, Greaves L, Hemsing N, Stinson J. Sex- and Gender-Based Analysis in Cannabis Treatment Outcomes: A Systematic Review. International Journal of Environmental Research and Public Health. 2020; 17(3):872. https://doi.org/10.3390/ijerph17030872

Chicago/Turabian Style

Brabete, Andreea C.; Greaves, Lorraine; Hemsing, Natalie; Stinson, Julie. 2020. "Sex- and Gender-Based Analysis in Cannabis Treatment Outcomes: A Systematic Review" Int. J. Environ. Res. Public Health 17, no. 3: 872. https://doi.org/10.3390/ijerph17030872

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