Next Article in Journal
Evaluation of Implementing a Home-Based Fall Prevention Program among Community-Dwelling Older Adults
Next Article in Special Issue
Increased Prevalence of Psychosocial, Behavioral, and Socio-Environmental Risk Factors among Overweight and Obese Youths in Mexico and the United States
Previous Article in Journal
Bibliometric Analysis of Algal-Bacterial Symbiosis in Wastewater Treatment
Previous Article in Special Issue
Measuring the Prevalence of Adverse Childhood Experiences by Survey Research Methods
Open AccessArticle

Association of Consecutive Influenza Vaccinations and Pneumonia: A Population-Based Case-Control Study

1
Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan
2
Department of Anesthesiology, Changhua Christian Hospital, Changhua 50006, Taiwan
3
Department of Microbiology and Immunology, Chung Shan Medical University, Taichung 40201, Taiwan
4
Department of Medical Research, Chung Shan Medical University Hospital, Taichung 40201, Taiwan
5
School of Medicine, Chang Gung University, Taoyuan City 33302, Taiwan
6
Graduate Institute of Oral Sciences, Chung Shan Medical University, Taichung 40201, Taiwan
7
School of Dentistry, Chung Shan Medical University, Taichung 40201, Taiwan
8
Department of Dentistry, Chung Shan Medical University Hospital, Taichung 40201, Taiwan
9
Department of Emergency Medicine, School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan
10
Department of Emergency Medicine, Chung Shan Medical University Hospital, Taichung 40201, Taiwan
11
Department of Health Policy and Management, Chung Shan Medical University, Taichung 40201, Taiwan
*
Author to whom correspondence should be addressed.
These authors contributed equally to the work.
Int. J. Environ. Res. Public Health 2019, 16(6), 1078; https://doi.org/10.3390/ijerph16061078
Received: 14 February 2019 / Revised: 15 March 2019 / Accepted: 23 March 2019 / Published: 26 March 2019
(This article belongs to the Special Issue IJERPH: 15th Anniversary)
The purpose of this study was to investigate whether individuals receiving influenza vaccines have a lower risk of pneumonia. A nationwide population-based case-control study was conducted using data from the National Health Insurance Research Database in Taiwan. We enrolled 7565 patients each in pneumonia and non-pneumonia groups after diagnosis of patients with chronic pulmonary disease, and these patients were individually age and sex matched in a 1:1 ratio. Using conditional logistic regression analysis, adjusted odds ratios (aORs) were estimated in patients who received influenza vaccination and those who had not previously had pneumonia. Moreover, we also analyzed the interval between vaccination and the onset of pneumonia and the number of vaccinations received by patients. This was compared with patients who never received influenza vaccination. Patients who had received influenza vaccination and had been vaccinated for two consecutive years (aOR = 0.85, confidence interval (CI) = 0.79–0.93 and aOR = 0.75, CI = 0.67–0.85, respectively) showed lower rates of pneumonia occurrence by 15–25%. In conclusion, influenza vaccination significantly reduces the occurrence of pneumonia, especially in individuals who receive vaccination in consecutive years. View Full-Text
Keywords: influenza vaccination; pneumonia; population-based case-control study influenza vaccination; pneumonia; population-based case-control study
Show Figures

Figure 1

MDPI and ACS Style

Yeh, L.-T.; Chan, C.-H.; Yang, S.-F.; Yeh, H.-W.; Yeh, Y.-T.; Wang, Y.-H.; Chou, M.-C.; Yeh, C.-B.; Teng, Y.-H. Association of Consecutive Influenza Vaccinations and Pneumonia: A Population-Based Case-Control Study. Int. J. Environ. Res. Public Health 2019, 16, 1078.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop