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Open AccessArticle

Estimation of the Human Extrathoracic Deposition Fraction of Inhaled Particles Using a Polyurethane Foam Collection Substrate in an IOM Sampler

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Rocky Mountain Center for Occupational & Environmental Health, Department of Family & Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA
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Department of Pediatrics, University of Utah, Salt Lake City, UT 84108, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Int. J. Environ. Res. Public Health 2016, 13(3), 292; https://doi.org/10.3390/ijerph13030292
Received: 13 February 2016 / Revised: 1 March 2016 / Accepted: 3 March 2016 / Published: 7 March 2016
Extrathoracic deposition of inhaled particles (i.e., in the head and throat) is an important exposure route for many hazardous materials. Current best practices for exposure assessment of aerosols in the workplace involve particle size selective sampling methods based on particle penetration into the human respiratory tract (i.e., inhalable or respirable sampling). However, the International Organization for Standardization (ISO) has recently adopted particle deposition sampling conventions (ISO 13138), including conventions for extrathoracic (ET) deposition into the anterior nasal passage (ET1) and the posterior nasal and oral passages (ET2). For this study, polyurethane foam was used as a collection substrate inside an inhalable aerosol sampler to provide an estimate of extrathoracic particle deposition. Aerosols of fused aluminum oxide (five sizes, 4.9 µm–44.3 µm) were used as a test dust in a low speed (0.2 m/s) wind tunnel. Samplers were placed on a rotating mannequin inside the wind tunnel to simulate orientation-averaged personal sampling. Collection efficiency data for the foam insert matched well to the extrathoracic deposition convention for the particle sizes tested. The concept of using a foam insert to match a particle deposition sampling convention was explored in this study and shows promise for future use as a sampling device. View Full-Text
Keywords: extrathoracic deposition; polyurethane foam; IOM sampler; inhalable particles; oral passage; nasal passage extrathoracic deposition; polyurethane foam; IOM sampler; inhalable particles; oral passage; nasal passage
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Sleeth, D.K.; Balthaser, S.A.; Collingwood, S.; Larson, R.R. Estimation of the Human Extrathoracic Deposition Fraction of Inhaled Particles Using a Polyurethane Foam Collection Substrate in an IOM Sampler. Int. J. Environ. Res. Public Health 2016, 13, 292.

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