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Correction published on 16 June 2015, see Int. J. Environ. Res. Public Health 2015, 12(6), 6892-6893.
Open AccessArticle

Monoamine Oxidase A Promoter Variable Number of Tandem Repeats (MAOA-uVNTR) in Alcoholics According to Lesch Typology

Institute of Psychology, Department of Clinical Psychology, University of Szczecin, Krakowska 69, 71-017 Szczecin, Poland
University Center for Education, University of Szczecin, Szwoleżerów 18a, 71-062 Szczecin, Poland
Department of Psychiatry, Pomeranian Medical University, Broniewskiego 26, 71-460 Szczecin, Poland
Department of Psychiatry, Vienna University, Waehringer Guertel 18–20, A-1090 Vienna, Austria
Department of Nursing, Pomeranian Medical University, Żołnierska 48, 71-210 Szczecin, Poland
Institute of Psychiatry and Neurology, Department of Pharmacology, Sobieskiego 9, 02-957 Warszawa, Poland
Department of Orthopedics, Pomeranian Medical University, Unii Lubelskiej 1, 71-460 Szczecin, Poland
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Int. J. Environ. Res. Public Health 2015, 12(3), 3317-3326;
Received: 8 January 2015 / Revised: 9 March 2015 / Accepted: 9 March 2015 / Published: 19 March 2015
Background: The aim of this study was to examine the association between the MAOA-uVNTR gene polymorphism in a homogeneous subgroups of patients with alcohol dependence categorized according to Lesch’s typology. Methods: DNA was provided from alcohol dependent (AD) patients (n = 370) and healthy control subjects (n = 168) all of Polish descent. The history of alcoholism was obtained using the Polish version of the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA). Samples were genotyped using PCR methods. Results: We found no association between alcohol dependence and MAOA gene polymorphism. Conclusions: Lesch typology is a clinical consequence of the disease and its phenotypic description is too complex for a simple genetic analysis. View Full-Text
Keywords: alcohol dependence; MAOA; Lesch’s typology alcohol dependence; MAOA; Lesch’s typology
MDPI and ACS Style

Samochowiec, A.; Chęć, M.; Kopaczewska, E.; Samochowiec, J.; Lesch, O.; Grochans, E.; Jasiewicz, A.; Bienkowski, P.; Kołodziej, Ł.; Grzywacz, A. Monoamine Oxidase A Promoter Variable Number of Tandem Repeats (MAOA-uVNTR) in Alcoholics According to Lesch Typology. Int. J. Environ. Res. Public Health 2015, 12, 3317-3326.

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