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Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.

Current Issues in Molecular Biology, Volume 9, Issue 1

January 2007 - 4 articles

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Review

1 Citations

1,040 Views

21 Pages

The Hepatitis C Virus NS3 Protein: A Model RNA Helicase and Potential Drug Target

David N. Frick

Curr. Issues Mol. Biol.2007, 9(1), 1-20;https://doi.org/10.21775/cimb.009.001

1 February 2007

The C-terminal portion of hepatitis C virus (HCV) nonstructural protein 3 (NS3) forms a three domain polypeptide that possesses the ability to travel along RNA or single-stranded DNA (ssDNA) in a 3' to 5' direction. Fueled by ATP hydrolysis, this mov...

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Review

1 Citations

2,445 Views

20 Pages

Molecular Diagnostics of Medically Important Bacterial Infections

Beverley Cherie Millar,
Jiru Xu and
John Edmund Moore

Curr. Issues Mol. Biol.2007, 9(1), 21-40;https://doi.org/10.21775/cimb.009.021

1 February 2007

Infectious diseases are common diseases all over the world. A recent World Health Organization report indicated that infectious diseases are now the world's biggest killer of children and young adults. Infectious diseases in non-industrialized countr...

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Review

5 Citations

1,320 Views

23 Pages

Biogenesis of Microbial Polyhydroxyalkanoate Granules: A Platform Technology for the Production of Tailor-Made Bioparticles

Bernd H.A. Rehm

Curr. Issues Mol. Biol.2007, 9(1), 41-62;https://doi.org/10.21775/cimb.009.041

1 February 2007

Biopolyester (PHAs = polyhydroxyalkanoates) composed of hydroxy fatty acids represent a rather complex class of storage polymers synthesized by various eubacteria and archaea and are deposited as water-insoluble cytoplasmic nano-sized inclusions. The...

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Review

1 Citations

999 Views

8 Pages

The Hepatitis C Virus NS2/3 Protease

Sarah Welbourn and
Arnim Pause

Curr. Issues Mol. Biol.2007, 9(1), 63-70;https://doi.org/10.21775/cimb.009.063

1 February 2007

The hepatitis C virus NS2/3 protein is a highly hydrophobic protease responsible for the cleavage of the viral polypeptide between non-structural proteins NS2 and NS3. However, many aspects of the NS2/3 protease's role in the viral life cycle and mec...

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