Perspective for Studying the Relationship of miRNAs with Transposable Elements
Abstract
:1. Introduction
2. Differences of the Origin of miRNA from Transposons in Plants from Animals
3. The Role of Transposons in the Emergence of miRNA in Animals
4. Prospects for the Creation of a Human Transposable Elements-Derived miRNA Database
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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№ | miRNA Designation | Transposon, miRNA Source [Author] | Diseases and Changes (Increased—↑; Decreased—↓) in miRNA Expression (Expressed Tissue) [Author] | miRNA Expression in Aging (Increased—↑; Decreased—↓) (Expressed Tissue) [Author] |
---|---|---|---|---|
(1) | miR-1183 | LINE/L2 [37,41] | ||
(2) | miR-1200 | SINE/MIR [33,37,41] | ||
(3) | miR-1202 | LTR/ERV1 [37,41]; LTR/MER52A [43] | ||
(4) | miR-1205 | SINE/MIR [33,37] | ||
(5) | miR-1246 | LTR/ERVL-MaLR [37,41] | ||
(6) | miR-1249 | LINE/L2 [35,37,41] | ↑: BLCA, HNSC, KIRC, LUSC, PRAD, STAD, UCEC; ↓: BRCA, COAD, READ, THCA (tumor tissue) [44] | |
(7) | miR-1254-1 | SINE/Alu [37,41] | ||
(8) | miR-1254-2 | |||
(9) | miR-1255a | DNA-TE/TcMar-Tigger [37,41] | ||
(10) | miR-1255b-1 | |||
(11) | miR-1255b-2 | |||
(12) | miR-1256 | |||
(13) | miR-1257 | LTR/ERVL-MaLR [37,41] | ||
(14) | miR-1260b | DNA-TE/TcMar-Tigger [37] | ||
(15) | miR-1261 | DNA-TE/TcMar-Tigger [37,41,43] | ||
(16) | miR-1263 | LTR/ERV1 [37,41] | ||
(17) | miR-1264 | LINE/L2 [33,37,41] | ||
(18) | miR-1266 | SINE/MIR [37,41] | ↑: BLCA, BRCA, CHOL, ESCA, KICH, KIRC, KIRP, LIHC, PRAD, STAD, UCEC; ↓: COAD (tumor tissue) [44] | |
(19) | miR-1267 | LTR/ERVL-MaLR [37,41] | ||
(20) | miR-1268a | SINE/Alu [37,41,43] | ||
(21) | miR-1268b | |||
(22) | miR-1269a | LTR/ERVL [35,37,41] | ↑: BLCA, BRCA, HNSC, LIHC, LUAD, LUSC, PRAD, STAD, THCA, UCEC; ↓: CHOL, KICH (tumor tissue) [44] | |
(23) | miR-1269b | LTR/ERVL [37,41] | ||
(24) | miR-1271 | LINE/L2 [35,37,41] | ↑: BLCA, ESCA, KIRC, LUSC; ↓: BRCA, COAD, KICH, LIHC, LUSC (tumor tissue) [44] | |
(25) | miR-1273a | SINE/Alu [37,41,43] | ||
(26) | miR-1273c | |||
(27) | miR-1273d | |||
(28) | miR-1273f | |||
(29) | miR-1273g | |||
(30) | miR-1273h | |||
(31) | miR-1285-1 | |||
(32) | miR-1285-2 | |||
(33) | miR-1289-1 | DNA-TE/hAT-Charlie [37,41] | ||
(34) | miR-1289-2 | |||
(35) | miR-1290 | DNA-TE/TcMar-Tigger [37,41] | ||
(36) | miR-1293 | SINE/Alu [33,37,41] | ||
(37) | miR-1296 | LINE/L2 [12] | ↑: BLCA, ESCA, LUSC, PRAD, UCEC; ↓: BRCA, COAD, KIRC, LIHC, READ, THCA (tumor tissue) [44] | |
(38) | miR-1298 | DNA-TE/X24 [41] | ||
(39) | miR-130a | LINE/L2 [43] | ||
(40) | miR-130b | SINE/MIR [29] | ||
(41) | miR-1302-1 | DNA/hAT [32,37,39,41,43] | ||
(42) | miR-1302-10 | DNA/hAT [32,37,39,41] | ||
(43) | miR-1302-11 | |||
(44) | miR-1302-2 | |||
(45) | miR-1302-3 | |||
(46) | miR-1302-4 | |||
(47) | miR-1302-5 | |||
(48) | miR-1302-6 | |||
(49) | miR-1302-7 | |||
(50) | miR-1302-8 | |||
(51) | miR-1302-9 | |||
(52) | miR-1303 | SINE/Alu [37,41,43] | ||
(53) | miR-1304 | |||
(54) | miR-1321 | SINE/MIR [37,41] | ||
(55) | miR-1343 | LINE/L2 [12] | ↓: IPF (lung tissue) [67] | |
(56) | miR-151a | LINE/L2 [29,35,37,43] | ↑: BLCA, BRCA, CESC, COAD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, PRAD, READ, STAD, UCEC (tumor tissue) [44] | ↓ (serum) [46] |
(57) | miR-151b | LINE/L2 [37,41,43] | ||
(58) | miR-1587 | LTR/ERVL-MaLR [37,41,43] | ||
(59) | miR-1825 | LINE/L2 [37,41] | ||
(60) | miR-1911 | LTR/Gypsy [33,37,41] | ↑: ESCA, HNSC, LUSC, STAD (tumor tissue) [44] | |
(61) | miR-192 | LINE/L2 [12] | ↑: BLCA, BRCA, COAD, KIRC, LUAD, LUSC, PRAD, READ, STAD, UCEC; ↓: CHOL, KICH, KIRP, LICH, THCA (tumor tissue) [44] | ↑ (kidney tissue) [47] |
(62) | miR-1972-1 | SINE/Alu [37,41,43] | ||
(63) | miR-1972-2 | |||
(64) | miR-2054 | DNA-TE/Helitron [37] | ||
(65) | miR-211 | LINE/L2 [12] | ↑: KIRC, KIRP, LIHC; ↓: BRCA, HNSC, LUAD (tumor tissue) [44] | ↑ (serum) [48] |
(66) | miR-2114 | LINE/CR1 [37] | ↑: BRCA, KIRC, LIHC (tumor tissue) [44] | |
(67) | miR-2115 | LINE/L1 [37,41] | ↑: BRCA (tumor tissue) [44] | |
(68) | miR-219-1 | LTR/Gypsy [37] | ||
(69) | miR-224 | DNA-TE/MER135 [37,41,43] | ↑: CESC, ESCA, HNSC, KIRC, LIHC, LUAD, LUSC, UCEC; ↓: BRCA, KICH (tumor tissue) [44] | |
(70) | miR-23c | SINE/tRNA [37] | ||
(71) | miR-2355 | LINE/RTE-BovB [37,41,43] | ↑: BLCA, COAD, ESCA, HNSC, KICH, KIRC, KIRP, LIHC, LUAD, LUSC, PRAD, READ, STAD, UCEC; ↓: LIHC, PAAD, THCA (tumor tissue) [44] | |
(72) | miR-28 | LINE/L2 [29,35,37,43] | ↑: HNSC, KIRC, LUAD, LUSC, PRAD; ↓: BRCA, CHOL, COAD, ESCA, PCPG, READ, STAD, THCA (tumor tissue) [44] | ↓ (blood) [49] |
(73) | miR-2909 | LTR/ERVL-MaLR [37,41] | ||
(74) | miR-302e | SINE/MIR [37,41,43] | ||
(75) | miR-31 | LINE/L2 [12] | ↑: BLCA, CESC, HNSC, KIRP, LUAD, LUSC, STAD, THCA, UCEC (tumor tissue) [44]; IPF (lung tissue) [66]; ↓: KICH, KIRC, PRAD (tumor tissue) [44] | ↑ endothelial cells [50], (breast tissue) [51] |
(76) | miR-302 | SINE/MIR [41] | ↑: IPF (lung tissue) [66] | |
(77) | miR-3116-1 | LINE/L2 [37,41] | ||
(78) | miR-3116-2 | |||
(79) | miR-3118-1 | LINE/L1 [37,41,43] | ||
(80) | miR-3118-2 | |||
(81) | miR-3118-3 | |||
(82) | miR-3118-4 | |||
(83) | miR-3118-5 | |||
(84) | miR-3118-6 | |||
(85) | miR-3133 | |||
(86) | miR-3134 | |||
(87) | miR-3135a | SINE/Alu [37,41] | ||
(88) | miR-3135b | |||
(89) | miR-3137 | DNA-TE/TcMar-Tigger [37,41] | ||
(90) | miR-3139 | LINE/L2 [37,41] | ||
(91) | miR-3144 | LINE/L1 [37,41,43] | ↑: HNSC, KICH (tumor tissue) [44] | |
(92) | miR-3149 | LINE/L1 [41] | ||
(93) | miR-3159 | SINE/Alu [37,41] | ||
(94) | miR-3161 | DNA-TE/hAT [37] | ||
(95) | miR-3163 | SINE/MIR [37,41] | ||
(96) | miR-3164 | DNA-TE/ TcMar-Tigger [41] | ||
(97) | miR-3166 | LINE/L2 [37,41] | ||
(98) | miR-3168 | SINE/MIR [37,41] | ||
(99) | miR-3169 | |||
(100) | miR-3174 | DNA-TE/hAT-Charlie [37,41] | ||
(101) | miR-3176 | LINE/L1 [37] | ||
(102) | miR-3179-1 | SINE/Alu [33,37,41] | ||
(103) | miR-3179-2 | SINE/Alu [33,37,41] | ||
(104) | miR-3179-3 | |||
(105) | miR-3185 | DNA-TE/hAT [37] | ||
(106) | miR-3194 | SINE/MIR [37,41] | ↑: STAD (tumor tissue) [44] | |
(107) | miR-3200 | ERV-L [35,37,41] | ↑: BLCA, BRCA, CHOL, HNSC, KIRP, LIHC, LUSC, STAD, UCEC; ↓: KIRC (tumor tissue) [44] | |
(108) | miR-3201 | LINE/L2 [37,41] | ||
(109) | miR-320b-2 | LINE/L2 [33,37,41] | ||
(110) | miR-320c-1 | LINE/RTE [37] | ||
(111) | miR-320c-2 | DNA-TE/Ginger2/TDD [37] | ||
(112) | miR-320d-1 | LINE/L1 [43] | ||
(113) | miR-320d-2 | LINE/CR1 [37] | ||
(114) | miR-325 | LINE/L2 [29,37,39,41] | ||
(115) | miR-326 | DNA-TE/hAT-Tip100 [37,41] | ↑: BLCA, KIRC, PCPG, UCEC; ↓: BRCA, COAD, KICH, LIHC, LUSC, READ, THCA (tumor tissue) [44]; IPF (lung tissue) [67] | |
(116) | miR-330 | SINE/MIR [29,37] | ||
(117) | miR-335 | SINE/MIR [33,37,41,43] | ↑: BLCA, COAD, ESCA, HNSC, LUAD, LUSC, PRAD, STAD, THCA, UCEC; ↓: BRCA, KICH, KIRC, LIHC (tumor tissue) [44]; IPF (lung tissue) [66] | ↑ (brain tissue) [52] |
(118) | miR-340 | DNA-TE/TcMar [35,37,41,43] | ↑: BRCA, COAD, KICH, KIRC, KIRP, LUAD, LUSC, PRAD, UCEC (tumor tissue) [44]; IPF (lung tissue) [70] ↓: CHOL, LIHC, PAAD (tumor tissue) [44] | ↑ (serum) [53] |
(119) | miR-342 | SINE/tRNA-RTE [35,37,41,43] | ↑: BLCA, BRCA, CESC, HNSC, KIRC, KIRP, PRAD, STAD, UCEC; ↓: COAD, LIHC, LUAD, PAAD, READ, THCA (tumor tissue) [44] | |
(120) | miR-345 | SINE/MIR [29,37] | ||
(121) | miR-361 | DNA-TE/hAT [37] | ||
(122) | miR-3611 | DNA/TcMar-Tigger [37,41] | ||
(123) | miR-3617 | SINE/MIR [37,41] | ||
(124) | miR-3622a | SINE/Alu [12] | ↓: LUAD (tumor tissue) [44] | |
(125) | miR-3622b | SINE/Alu [37,41] | ||
(126) | miR-3646 | SINE/MIR [33,37] | ||
(127) | miR-3648 | DNA-TE/MER [37] | ||
(128) | miR-3657 | LINE/L1 [37,41] | ||
(129) | miR-3664 | DNA-TE/TcMar-Tigger [33,37,41] | ||
(130) | miR-3665 | DNA-TE/EnSpm [37] | ||
(131) | miR-3667 | LTR/ERVL-MaLR [37,41] | ||
(132) | miR-3668 | SINE/MIR [33,37] | ||
(133) | miR-3670-1 | LTR/ERVL [37,41] | ||
(134) | miR-3670-2 | |||
(135) | miR-3672 | LINE/L1 [37,41] | ||
(136) | miR-3674 | LTR/ERV1 [37,41] | ||
(137) | miR-3680-1 | DNA-TE/hAT-Tip100 [41] | ||
(138) | miR-3680-2 | |||
(139) | miR-3681 | LTR/ERVL [37,41] | ||
(140) | miR-3686 | LINE/L1 [37,41] | ||
(141) | miR-3689c | LINE/L1 [37] | ||
(142) | miR-370 | SINE/MIR [29,37] | ||
(143) | miR-3713 | DNA/TcMar-Tigger [37,41] | ||
(144) | miR-374a | LINE/L2 [37,41,43] | ↑: BLCA, BRCA, COAD, KIRC, KIRP, PRAD, READ, STAD; ↓: CHOL, HNSC, LUSC (tumor tissue) [44]; ↓: IPF (lung tissue) [66] | |
(145) | miR-374b | LINE/L2 [29,37] | ↑: BLCA, BRCA, COAD, ESCA, HNSC, KIRC, KIRP, PRAD, STAD, UCEC; ↓: THCA (tumor tissue) [44] | |
(146) | miR-374c | LINE/L2 [37,41] | ||
(147) | miR-378a | SINE/MIR [29,37,43] | ↑: PAAD; ↓: BRCA, CHOL, COAD, HNSC, LIHC, LUAD, PAAD, PRAD, READ, STAD (tumor tissue) [44] | ↑ (thymus tissue) [54] |
(148) | miR-378b | SINE/MIR [37,41,43] | ||
(149) | miR-378d-1 | |||
(150) | miR-378d-2 | |||
(151) | miR-378e | |||
(152) | miR-378f | |||
(153) | miR-378g | |||
(154) | miR-378h | |||
(155) | miR-378i | SINE/MIR [37,43] | ||
(156) | miR-3908 | SINE/Alu [37,41] | ||
(157) | miR-3909 | LINE/L2 [12,37] | ↑: LIHC (tumor tissue) [44] | |
(158) | miR-3910-1 | LINE/L1 [37,41] | ||
(159) | miR-3910-2 | |||
(160) | miR-3912 | |||
(161) | miR-3915 | |||
(162) | miR-3919 | LINE/L1 [37] | ||
(163) | miR-3920 | LINE/L2 [33,37,41] | ||
(164) | miR-3921 | LINE/L2 [33,37] | ||
(165) | miR-3923 | LTR/ERVL-MaLR [37,41] | ||
(166) | miR-3925 | DNA-TE/TcMar-Tigger [37,41] | ||
(167) | miR-3927 | LTR/ERVL-MaLR [37,41] | ||
(168) | miR-3929 | SINE/Alu [37,41] | ||
(169) | miR-3934 | SINE/MIR [35,37,41] | ↑: BRCA, HNSC, KIRC, LUSC, STAD, UCEC (tumor tissue) [44] | |
(170) | miR-3936 | LTR/ERVL [33,35,37,41] | ||
(171) | miR-3937 | LTR/ERV3 [37] | ||
(172) | miR-3972 | DNA-TE/hAT-Tip100 [37,41] | ||
(173) | miR-3973 | DNA-TE/TcMar-Tigger [41] | ||
(174) | miR-3977 | DNA-TE/hAT-Tip100 [41] | ||
(175) | miR-421 | LINE/L2 [29,35,37,43] | ↑: BLCA, BRCA, ESCA, HNSC, KIRP, LIHC, LUAD, LUSC, STAD, UCEC; ↓: THCA (tumor tissue) [44] | |
(176) | miR-422a | SINE/MIR [37,41] | ||
(177) | miR-4263 | LINE/L1 [37,41] | ||
(178) | miR-4281 | LTR/ERV1 [37] | ||
(179) | miR-4286 | LTR/ERV3 [37] | ||
(180) | miR-4288 | LTR/ERVL [33,37,41] | ||
(181) | miR-4293 | SINE/tRNA [37,41] | ||
(182) | miR-4311 | LINE/L2 [41] | ||
(183) | miR-4317 | SINE/MIR [33,37] | ||
(184) | miR-4418 | LINE/L2 [37,41] | ||
(185) | miR-4419a | SINE/Alu [37,41] | ||
(186) | miR-4419b | |||
(187) | miR-4420 | SINE/MIR [37,41] | ||
(188) | miR-4421 | LTR/ERV1 [37,41] | ||
(189) | miR-4422 | LTR/Gypsy [37,41] | ||
(190) | miR-4424 | LINE/L1 [37,41] | ||
(191) | miR-4425 | SINE/MIR [37,41] | ||
(192) | miR-4428 | LTR/ERV1 [37,41] | ||
(193) | miR-4430 | SINE/Alu [37,41] | ||
(194) | miR-4431 | LTR/ERVL-MaLR [37,41] | ||
(195) | miR-4433 | LINE/L2 [37,41] | ||
(196) | miR-4433b | |||
(197) | miR-4438 | LINE/L1 [37,41] | ||
(198) | miR-4445 | |||
(199) | miR-4447 | DNA-TE/hAT-Charlie [37,41] | ||
(200) | miR-4448 | LTR/ERVK [37,41] | ||
(201) | miR-4452 | SINE/Alu [37,41,43] | ||
(202) | miR-4454 | LTR/ERV1 [37,41] | ||
(203) | miR-4455 | LINE/L1 [37,41] | ||
(204) | miR-4457 | |||
(205) | miR-4459 | SINE/Alu [37,41] | ||
(206) | miR-4460 | LTR/ERVL [37,41] | ||
(207) | miR-4463 | DNA-TE/hAT-Charlie [37,41] | ||
(208) | miR-4468 | LINE/R1 [37] | ||
(209) | miR-4472-2 | SINE/Alu [37,41] | ||
(210) | miR-4477a | DNA-TE/TcMar-Tigger [37,41] | ||
(211) | miR-4477b | |||
(212) | miR-4480 | SINE/MIR [37,41] | ||
(213) | miR-4481 | LTR/ERVL-MaLR [37,41] | ||
(214) | miR-4483 | SINE/Alu [37,41] | ||
(215) | miR-4484 | LTR/ERV1 [37,41] | ||
(216) | miR-4491 | DNA-TE/hAT-Blackjack [37,41] | ||
(217) | miR-4494 | DNA-TE/TcMar-Tigger [37,41] | ||
(218) | miR-4495 | SINE/MIR [37,41] | ||
(219) | miR-4496 | |||
(220) | miR-450b | LINE/L1 [33,35,37,41,43] | ↑: BLCA, BRCA, COAD, ESCA, HNSC, KIRC, LUAD, LUSC, READ, STAD, THCA; ↓: CHOL, KICH, KIRP, LIHC, PRAD, UCEC (tumor tissue) [44] | ↓ (liver tissue) [55] |
(221) | miR-4501 | SINE/MIR [37,41] | ||
(222) | miR-4502 | DNA-TE/TcMar-Tigger [37,41] | ||
(223) | miR-4504 | LINE/L1 [37,41] | ||
(224) | miR-4506 | SINE/MIR [37,41] | ||
(225) | miR-4507 | DNA-TE/P-1 [37] | ||
(226) | miR-4508 | SINE [37] | ||
(227) | miR-4510 | LINE/L2 [37,41] | ||
(228) | miR-4512 | SINE/Alu [37,41] | ||
(229) | miR-4518 | DNA/hAT-Charlie [37,41] | ||
(230) | miR-4520a | SINE/MIR [37,41] | ||
(231) | miR-4520b | SINE/tRNA [37] | ||
(232) | miR-4525 | LTR/ERV1 [37,41] | ||
(233) | miR-4527 | LTR/ERVL-MaLR [37,41] | ||
(234) | miR-4537 | DNA-TE/P-1 [37] | ||
(235) | miR-4538 | DNA-TE/P-1 [37] | ||
(236) | miR-4640 | LTR/Copia [37] | ||
(237) | miR-4656 | SINE/tRNA [37] | ||
(238) | miR-466 | LINE/L1 [37,41,43] | ||
(239) | miR-4661 | LTR/Gypsy [41] | ||
(240) | miR-4662a | LINE/L1 [37,41] | ||
(241) | miR-4662b | |||
(242) | miR-4666b | LTR/ERVL-MaLR [41] | ||
(243) | miR-4671 | SINE/tRNA-RTE [41] | ||
(244) | miR-4672 | SINE/MIR [37,41] | ||
(245) | miR-4676 | LINE/L2 [37,41] | ||
(246) | miR-4684 | DNA-TE/hAT-Charlie [37,41] | ||
(247) | miR-4699 | LINE/L2 [37,41] | ||
(248) | miR-4703 | DNA-TE/TcMar-Tigger [41] | ||
(249) | miR-4704 | LTR/ERVL-MaLR [37,41] | ||
(250) | miR-4712 | SINE-MIR [37,41] | ||
(251) | miR-4731 | LINE/CR1 [37,41] | ||
(252) | miR-4739 | LTR/Gypsy [37] | ||
(253) | miR-4750 | LINE/CR1 [37] | ||
(254) | miR-4753 | LINE/L1 [37,41] | ||
(255) | miR-4756 | DNA/hAT-Tip100 [37,41] | ||
(256) | miR-4771-1 | LINE/L1 [37] | ||
(257) | miR-4771-2 | |||
(258) | miR-4772 | LINE/L1 [37,41] | ||
(259) | miR-4775 | DNA-TE/TcMar-Tc1 [41] | ||
(260) | miR-4786 | LINE/L1 [37,41] | ||
(261) | miR-4797 | SINE/5S-Deu-L2 [41] | ||
(262) | miR-4800 | DNA-TE/Sola [37] | ||
(263) | miR-4801 | SINE/MIR [37,41] | ||
(264) | miR-487b | SINE/MIR [33,37,41] | ↑: LUAD, LUSC (tumor tissue) [44]; IPF (lung tissue) [71]; ↓: BRCA, HNSC, KICH, KIRC, KIRP, LIHC, PRAD, THCA, UCEC (tumor tissue) [44] | ↑ (skeletal muscles) [56] |
(265) | miR-493 | LINE/L2 [29,35,37] | ↑: BRCA, ESCA, LUAD, LUSC, READ, STAD (tumor tissue) [44]; IPF (lung tissue) [71] ↓: KICH, KIRC, KIRP, LIHC, PRAD (tumor tissue) [44] | |
(266) | miR-495 | ERV-L/MaLR [12] | ↑: COAD, LUAD, READ (tumor tissue) [44]; IPF (lung tissue) [71]; ↓: BRCA, HNSC, KICH, KIRC, KIRP, LIHC, THCA, UCEC (tumor tissue) [44] | ↑ (mesenchymal stem cells) [57] |
(267) | miR-4999 | LINE/L1 [41] | ||
(268) | miR-5003 | SINE/MIR [41] | ||
(269) | miR-5007 | LTR/ERVL-MaLR [41] | ||
(270) | miR-5009 | DNA-TE/TcMar-Tigger [41] | ||
(271) | miR-5011 | |||
(272) | miR-502 | LINE/L2 [12] | ↑: BLCA, LIHC, PRAD, STAD, UCEC; ↓: COAD, KIRC, KIRP, LUSC, PAAD, THCA (tumor tissue) [44] | |
(273) | miR-5094 | SINE/Alu [41] | ||
(274) | miR-5095 | SINE/Alu [37,41] | ||
(275) | miR-5096 | |||
(276) | miR-5100 | SINE/MIR | ||
(277) | miR-511 | LINE/L1 [12] | ↑: HNSC, PRAD, READ, STAD; ↓: BRCA, CHOL, KICH, KIRP, LIHC, LUSC, PCPG (tumor tissue) [44] | ↑ (brain tissue) [58] |
(278) | miR-513a-1 | DNA-TE/MER [37,43] | ||
(279) | miR-513a-2 | |||
(280) | miR-513b | |||
(281) | miR-513c | |||
(282) | miR-517a | SINE/Alu [10] | ↓: LUAD (tumor tissue) [44] | |
(283) | miR-518d | LINE/RTE [43] | ||
(284) | miR-520d | SINE/Alu [12] | ↑: LIHC (tumor tissue) [44] | |
(285) | miR-544a | DNA-TE/hAT-Charlie [37,41,43] | ||
(286) | miR-544b | |||
(287) | miR-545 | LINE/L2 [29,35,37,43] | ↑: BRCA, KIRC, LIHC, READ (tumor tissue) [44] | |
(288) | miR-548a-1 | DNA-TE/TcMar-Mariner [37,41,43] | ||
(289) | miR-548a-2 | |||
(290) | miR-548a-3 | |||
(291) | miR-548aa-1 | |||
(292) | miR-548aa-2 | |||
(293) | miR-548ab | |||
(294) | miR-548ac | |||
(295) | miR-548ad | |||
(296) | miR-548ae-1 | |||
(297) | miR-548ae-2 | |||
(298) | miR-548ag-1 | |||
(299) | miR-548ag-2 | |||
(300) | miR-548ah | |||
(301) | miR-548ai | |||
(302) | miR-548aj-1 | |||
(303) | miR-548aj-2 | |||
(304) | miR-548ak | |||
(305) | miR-548al | |||
(306) | miR-548am | |||
(307) | miR-548an | |||
(308) | miR-548ao | |||
(309) | miR-548ap | |||
(310) | miR-548aq | |||
(311) | miR-548ar | |||
(312) | miR-548as | DNA-TE/TcMar-Mariner [41] | ||
(313) | miR-548at | |||
(314) | miR-548au | |||
(315) | miR-548av | |||
(316) | miR-548aw | |||
(317) | miR-548ax | |||
(318) | miR-548ay | |||
(319) | miR-548az | |||
(320) | miR-548b | |||
(321) | miR-548ba | |||
(322) | miR-548c | |||
(323) | miR-548d-1 | |||
(324) | miR-548d-2 | |||
(325) | miR-548e | |||
(326) | miR-548f-1 | |||
(327) | miR-548f-2 | |||
(328) | miR-548f-3 | DNA-TE/TcMar-Mariner [41] | ||
(329) | miR-548f-4 | |||
(330) | miR-548f-5 | |||
(331) | miR-548g | |||
(332) | miR-548h-1 | |||
(333) | miR-548h-2 | |||
(334) | miR-548h-3 | |||
(335) | miR-548h-4 | |||
(336) | miR-548h-5 | |||
(337) | miR-548i-1 | |||
(338) | miR-548i-2 | |||
(339) | miR-548i-3 | |||
(340) | miR-548i-4 | |||
(341) | miR-548j | |||
(342) | miR-548k | |||
(343) | miR-548l | |||
(344) | miR-548m | |||
(345) | miR-548n | DNA-TE/TcMar-Mariner [39,41] | ||
(346) | miR-548o | |||
(347) | miR-548o-2 | |||
(348) | miR-548p | |||
(349) | miR-548q | |||
(350) | miR-548s | |||
(351) | miR-548t | |||
(352) | miR-548u | |||
(353) | miR-548v | |||
(354) | miR-548w | |||
(355) | miR-548x | |||
(356) | miR-548x-2 | |||
(357) | miR-548y | |||
(358) | miR-548z | |||
(359) | miR-549a | SINE/MIR [33,41] | ||
(360) | miR-551a | LINE/L1 [12] | ↑: BRCA, LUAD, LUSC, STAD (tumor tissue) [44] | |
(361) | miR-552 | LINE/L1 [29,37,41] | ↑: LIHC, READ, STAD (tumor tissue) [44] | |
(362) | miR-553 | SINE/MIR [33,41] | ||
(363) | miR-558 | LTR/ERVL-MaLR [37,39,41] | ||
(364) | miR-5584 | SINE/MIR [41] | ||
(365) | miR-5585 | SINE/Alu [41] | ||
(366) | miR-5586 | LINE/L1 [41] | ||
(367) | miR-5589 | DNA-TE/hAT-Tip100 [41] | ||
(368) | miR-5590 | LINE/L1 [41] | ||
(369) | miR-5591 | |||
(370) | miR-562 | LINE/L1 [37] | ||
(371) | miR-566 | SINE/Alu [37,41] | ||
(372) | miR-568 | DNA-TE/Tc1-Mariner [37] | ||
(373) | miR-5681a | SINE/MIR [41] | ||
(374) | miR-5682 | LINE/L1 [41] | ||
(375) | miR-5683 | DNA-TE/hAT-Charlie [41] | ||
(376) | miR-5684 | SINE/Alu [41] | ||
(377) | miR-5689 | |||
(378) | miR-5691 | DNA-TE/hAT-Cahrlie [41] | ||
(379) | miR-5694 | LTR/ERVL [41] | ||
(380) | miR-5695 | LTR-ERV1 [41] | ||
(381) | miR-5697 | LINE/L1 [41] | ||
(382) | miR-5698 | |||
(383) | miR-570 | DNA-TE/TcMar-Mariner [37,41,43] | ||
(384) | miR-5700 | LINE/L2 [41] | ||
(385) | miR-5706 | DNA/TcMar-Tigger [41] | ||
(386) | miR-5708 | SINE/Alu [41] | ||
(387) | miR-571 | LINE/L1 [37,41] | ||
(388) | miR-575 | SINE [37] | ||
(389) | miR-576 | LINE/L1 [29,37] | ↑: BLCA, BRCA, ESCA, HNSC, KICH, KIRC, KIRP, LUAD, LUSC, PRAD, READ, STAD, UCEC; ↓: CHOL, LIHC, THCA (tumor tissue) [44] | ↑ (blood plasma) [59] |
(390) | miR-577 | LINE/L2 [33,37,41] | ↑: BLCA, CHOL, COAD, HNSC, KICH, LUAD, LUSC, READ, STAD, UCEC; ↓: KIRC, KIRP, THCA (tumor tissue) [44] | |
(391) | miR-578 | LINE/CR1 [37] | ||
(392) | miR-579 | DNA-TE/TcMar-Mariner [37,41] | ||
(393) | miR-581 | DNA-TE/hAT-Charlie [33,37,41] | ||
(394) | miR-582 | LINE/CR1 [29,35,37] | ↑: BRCA, COAD, KICH, PRAD, READ; ↓: CHOL, HNSC, LIHC, THCA (tumor tissue) [44] | |
(395) | miR-584 | DNA-TE/hAT-Blackjack [29,35,37] | ↑: BLCA, ESCA, HNSC, KICH, KIRC, KIRP, PRAD, STAD; ↓: BRCA, LUAD, THCA (tumor tissue) [44] | |
(396) | miR-585 | ERV-L/MaLR [37,41] | ↓: BRCA, KICH, KIRC, THCA (tumor tissue) [44] | ↑ (endothelial cells) [60] |
(397) | miR-587 | DNA-TE/hAT [37] | ||
(398) | miR-588 | LINE/L1 [37,41] | ||
(399) | miR-591 | DNA-TE/hAT-Charlie [33,37,41] | ||
(400) | miR-598 | DNA-TE/CACTA LP [37] | ||
(401) | miR-603 | DNA-TE/TcMar-Mariner [37,41,43] | ||
(402) | miR-606 | LINE/L1 [37,41] | ||
(403) | miR-607 | SINE/MIR [29,37,41] | ||
(404) | miR-608 | LINE/L2 [33,37] | ||
(405) | miR-6088 | SINE/Alu [41] | ||
(406) | miR-612 | SINE/MIR [33,37,41] | ||
(407) | miR-6127 | SINE/MIR [41] | ||
(408) | miR-6130 | LINE/L1 [41] | ||
(409) | miR-616 | LINE/L2 [35,37,41] | ↑: KICH, KIRC, KIRP, LUSC, UCEC; ↓: CHOL, LIHC (tumor tissue) [44] | |
(410) | miR-619 | LINE/L1; SINE/Alu [35,37,39,41,43] | ||
(411) | miR-625 | LINE/L1 [35,37,41] | ||
(412) | miR-626 | |||
(413) | miR-630 | SINE/MIR [12] | ↓: IPF (lung tissue) [68] | |
(414) | miR-6303 | DNA-TE/MADE1 [43] | ||
(415) | miR-633 | SINE/MIR [35,37,41] | ||
(416) | miR-634 | LINE/L1 [37,41] | ||
(417) | miR-637 | LINE/L1 [33,37,41,43] | ||
(418) | miR-638 | DNA-TE/hAT [37] | ||
(419) | miR-640 | SINE/MIR [37,41] | ||
(420) | miR-644a | LINE/L1 [37,41] | ||
(421) | miR-645 | DNA-TE/hAT-Charlie [37,41] | ||
(422) | miR-646 | LTR/ERVL [37,41] | ||
(423) | miR-649 | DNA-TE/TcMar-Tigger [37,39,41] | ||
(424) | miR-6500 | LTR/ERV1 [41] | ||
(425) | miR-6503 | LTR/ERVL-MaLR [41] | ||
(426) | miR-6507 | LINE/L1 [41] | ||
(427) | miR-652 | DNA/hAT-Tip100 [29,35,37,43]. | ↑: BLCA, ESCA, HNSC, LIHC, STAD, THCA, UCEC; ↓: COAD, KICH, LUAD, LUSC, THCA (tumor tissue) [44] | |
(428) | miR-659 | DNA-TE/hAT-Tip100 [37,41] | ||
(429) | miR-663 | LINE/I [37] | ||
(430) | miR-663b | LTR/Gypsy [37] | ||
(431) | miR-6745 | LINE/L2 [41] | ||
(432) | miR-6839 | LTR/ERV1 [41] | ||
(433) | miR-6854 | DNA-TE/hAT-Charlie [41] | ||
(434) | miR-6887 | LINE/L2 [41] | ||
(435) | miR-708 | LINE/L2 [35,37,41] | ↑: BLCA, BRCA, CHOL, COAD, HNSC, KIRC, LUAD, LUSC, PRAD, READ, STAD; ↓: KICH, THCA (tumor tissue) [44]; IPF (lung tissue) [69] | ↑ (spleen tissue) [62] |
(436) | miR-7151 | LINE/L1 [41] | ||
(437) | miR-7157 | |||
(438) | miR-720 | LTR/ERV1 [37] | ||
(439) | miR-769 | LINE/CR1 [12] | ↑: BLCA, BRCA, ESCA, HNSC, KIRC, KIRP, LIHC, LUSC, PRAD, STAD, UCEC; ↓: COAD (tumor tissue) [44] | |
(440) | miR-7702 | LINE/RTE-BovB [41] | ||
(441) | miR-7849 | LTR/ERVL-MaLR [41] | ||
(442) | miR-7850 | |||
(443) | miR-7851 | SINE/Alu [41] | ||
(444) | miR-7853 | DNA-TE/hAT-Cahrlie [41] | ||
(445) | miR-7973-1 | SINE/MIR [41] | ||
(446) | miR-7973-2 | |||
(447) | miR-7975 | LTR/ERV1 [41] | ||
(448) | miR-7977 | |||
(449) | miR-7978 | LINE/L1 [41] | ||
(450) | miR-8056 | LINE/L2 [41] | ||
(451) | miR-8067 | LINE/L1 [41] | ||
(452) | miR-8074 | |||
(453) | miR-8076 | SINE/MIR [41] | ||
(454) | miR-8079 | SINE/MIR [41] | ||
(455) | miR-8084 | LINE/L1 [41] | ||
(456) | miR-8086 | SINE/Alu [41] | ||
(457) | miR-877 | LINE/L1 [37] | ||
(458) | miR-885 | SINE/MIR [37,41] | ↑: KICH; ↓: CHOL (tumor tissue) [44] | ↑ (blood) [61] |
(459) | miR-887 | LINE/L2 [37,41] | ↑: BRCA; ↓: HNSC, KICH, KIRP, PAAD, THCA (tumor tissue) [44] | |
(460) | miR-891a | SINE/MIR [33,37,41] | ||
(461) | miR-891b | |||
(462) | miR-921 | SINE/MIR [37,41] | ||
(463) | miR-924 | LTR/ERV1 [37] | ||
(464) | miR-941-1 | LTR/Gypsy [37] | ||
(465) | miR-941-3 | |||
(466) | miR-941-4 | |||
(467) | miR-95 | LINE/L2 [29,37,43] | ↑: CHOL, COAD, PRAD, READ, STAD, UCEC; ↓: HNSC, KICH, PCPG, THCA (tumor tissue) [44] |
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Mustafin, R.N.; Khusnutdinova, E. Perspective for Studying the Relationship of miRNAs with Transposable Elements. Curr. Issues Mol. Biol. 2023, 45, 3122-3145. https://doi.org/10.3390/cimb45040204
Mustafin RN, Khusnutdinova E. Perspective for Studying the Relationship of miRNAs with Transposable Elements. Current Issues in Molecular Biology. 2023; 45(4):3122-3145. https://doi.org/10.3390/cimb45040204
Chicago/Turabian StyleMustafin, Rustam Nailevich, and Elza Khusnutdinova. 2023. "Perspective for Studying the Relationship of miRNAs with Transposable Elements" Current Issues in Molecular Biology 45, no. 4: 3122-3145. https://doi.org/10.3390/cimb45040204