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Sensors 2018, 18(1), 264; https://doi.org/10.3390/s18010264

Time Domain Near Infrared Spectroscopy Device for Monitoring Muscle Oxidative Metabolism: Custom Probe and In Vivo Applications

1
Dipartimento di Fisica, Politecnico di Milano, Piazza Leonardo da Vinci, 32, 20133 Milan, Italy
2
Istituto di Fotonica e Nanotecnologie, Consiglio Nazionale delle Ricerche, Piazza Leonardo da Vinci, 32, 20133 Milan, Italy
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 16 November 2017 / Revised: 9 January 2018 / Accepted: 15 January 2018 / Published: 17 January 2018
(This article belongs to the Special Issue Biomedical Sensors and Systems 2017)
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Abstract

Measurement of muscle oxidative metabolism is of interest for monitoring the training status in athletes and the rehabilitation process in patients. Time domain near infrared spectroscopy (TD NIRS) is an optical technique that allows the non-invasive measurement of the hemodynamic parameters in muscular tissue: concentrations of oxy- and deoxy-hemoglobin, total hemoglobin content, and tissue oxygen saturation. In this paper, we present a novel TD NIRS medical device for muscle oxidative metabolism. A custom-printed 3D probe, able to host optical elements for signal acquisition from muscle, was develop for TD NIRS in vivo measurements. The system was widely characterized on solid phantoms and during in vivo protocols on healthy subjects. In particular, we tested the in vivo repeatability of the measurements to quantify the error that we can have by repositioning the probe. Furthermore, we considered a series of acquisitions on different muscles that were not yet previously performed with this custom probe: a venous-arterial cuff occlusion of the arm muscle, a cycling exercise, and an isometric contraction of the vastus lateralis. View Full-Text
Keywords: time domain near infrared spectroscopy; muscle oxidative metabolism; total hemoglobin; tissue oxygen saturation time domain near infrared spectroscopy; muscle oxidative metabolism; total hemoglobin; tissue oxygen saturation
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Re, R.; Pirovano, I.; Contini, D.; Spinelli, L.; Torricelli, A. Time Domain Near Infrared Spectroscopy Device for Monitoring Muscle Oxidative Metabolism: Custom Probe and In Vivo Applications. Sensors 2018, 18, 264.

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